Results 201 to 210 of about 436,888 (278)

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

Advanced Science, Volume 13, Issue 50, 7 September 2026.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai, Hongming Huang, Xudong Hang, Shanwei Hu, Qian Tong, Jingchen Xu, Jia Jia, Hongkai Bi   +7 more
wiley   +1 more source

Exploiting induced pluripotent stem cell-derived retinal pigment epithelium to unravel host-pathogen interaction in ocular tuberculosis: a reverse translational <i>in vitro</i> model. [PDF]

Front Ophthalmol (Lausanne)
Putera I, van de Meerendonk S, Nagtzaam NMA, La Distia Nora R, Rombach SM, de Steenwinkel JEM, Vingerling JR, Dik WA, van Hagen PM.   +8 more
europepmc   +1 more source

Ocular Tuberculosis Without a Lung Primary. [PDF]

Cureus, 2020
Nandu NS, Bavanasi A, Wajahat R.
europepmc   +1 more source

Conformational Snapshots of CydDC in a Native Lipid Bilayer Coupling Heme Transport to Antibiotic Resistance

Advanced Science, Volume 13, Issue 50, 7 September 2026.
Phylogenetic and biochemical analyses of the heme transporter CydDC reveal its functional conservation throughout bacterial evolution and demonstrate its unique asymmetric allosteric mechanism. Furthermore, impairment of CydDC function directly affects bacterial antibiotic resistance and likely compromises antibiotic efficacy through drug efflux.
Lili Yang, Changbin Zhang, Mengyuan Lyu, Yongbo Luo, Jierou Zhang, Yujiao Chen, Lintao Luo, Wen Qiao, Xiangyangpeng Li, Yu Zhou, Zhongling Wei, Yuling Xiao, Qian Niu, Juan Zhou, Guanglin He, Binwu Ying, Zhaoming Su, Hao Chen, Xiaodi Tang, Haohao Dong   +19 more
wiley   +1 more source

Exploring the Molecular Intersection of Posterior Ocular Tuberculosis: <i>Mycobacterium tuberculosis</i> Proteins, Ocular Autoimmunity, and Immune Receptor Interactions. [PDF]

Ophthalmol Sci
Kutlutürk Karagöz I, Kaya M, Kıvrak U, Munk MR.   +3 more
europepmc   +1 more source

Incidence of dementia and mild cognitive impairment in two Indigenous Bolivian cohorts

Alzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract INTRODUCTION We studied dementia incidence and risk factors in Indigenous Tsimane and Moseten Amerindian populations in Amazonian Bolivia with largely subsistence lifestyles. METHODS A median of 4.7 years after baseline dementia assessment, 730 participants (52% male; mean age 67.3 years) were re‐visited at two follow‐up phases to determine ...
Margaret Gatz, Wendy J. Mack, Daniel Eid Rodriguez, Raul Quispe Gutierrez, Jesus Bani Cuata, Helena C. Chui, Ellen E. Walters, Daniel K. Cummings, Paul L. Hooper, Henrik Zetterberg, Caleb E. Finch, Benjamin C. Trumble, Jonathan Stieglitz, Michael D. Gurven, Randall C. Thompson, Gregory S. Thomas, The HORUS Team, Tsimane Health and Life History Project, Hillard S. Kaplan   +18 more
wiley   +1 more source

Characterization of and advanced diagnostic methods for ocular tuberculosis and tuberculosis. [PDF]

Int J Ophthalmol, 2020
Yan WJ, Zhou HY, Yan H.
europepmc   +1 more source

From Identification to Enzymatic Activity Profiling: Comprehensive Characterization of BloCAβ, a Probiotic β‐Carbonic Anhydrase From Bifidobacterium longum

Archiv der Pharmazie, Volume 359, Issue 9, September 2026.
Production and biochemical characterization of a new β‐carbonic anhydrase from the probiotic Bifidobacterium longum, one of the main players of human gut microbiota. ABSTRACT The microbiota comprises communities of microorganisms that establish complex relationships with the host and play key roles in physiology, metabolism, and immunity.
Simone Giovannuzzi, Andrea Ammara, Simone Carradori, Viviana De Luca, Marialucia Gallorini, Damiano Iacovozzi, Amelia Cataldi, Ilaria D'Agostino, Davide Moi, Valentina Onnis, Claudiu T. Supuran, Clemente Capasso   +11 more
wiley   +1 more source

Ocular tuberculosis with Mycobacterium tuberculosis DNA presence in ocular fluid: will post-COVID era bring a difference? [PDF]

Eye (Lond)
Putera I, Widodo E, Riasanti M, Waliyuddin MZ, Sitompul R, Edwar L, Susiyanti M, Aziza Y, Yasmon A, van Hagen PM, La Distia Nora R.   +10 more
europepmc   +1 more source