Results 91 to 100 of about 7,290 (223)

RESPONS IMUN PADA KARIES DAN PERAN ODONTOBLAST DALAM RESPONS IMUN [PDF]

, 2016
Karies yang tidak dirawat akan dapat berlanjut ke dentin, dan mayoritas ditemukan bakteri gram positif dan gram negatif pada kavitas gigi. Difusi bakteri patogen melalui produk toksin bakteri akan masuk ke dalam tubulus dentin sehingga menyebabkan ...
Octiara, Essie
core   +1 more source

In Vivo Base Editing Partially Rescues Bone Dysplasia in a Mouse Model of Hutchinson‐Gilford Progeria Syndrome

Aging Cell, Volume 25, Issue 9, September 2026.
Hutchinson‐Gilford progeria syndrome (HGPS) is a premature aging disorder caused by a mutation in LMNA that produces the toxic progerin protein. In this study, an adenine base editor delivered via AAV9 achieved partial gene correction in HGPS mice when given at two weeks of age, partially rescuing bone structural and gene expression parameters and ...
Wayne A. Cabral, Caleb M. Grenko, Diana Yeritsyan, Indeevar Beeram, Shubham Laiwala, Lukas R. Johnson, Urraca L. Tavarez, Tingfen Yan, Stephen M. Wincovitch, Luke W. Koblan, Xin D. Gao, Meirui An, Narisu Narisu, Leslie G. Biesecker, David R. Liu, Ara Nazarian, Francis S. Collins, Michael R. Erdos   +17 more
wiley   +1 more source

MicroRNA Regulation of DLX3 during Odontoblast Differentiation [PDF]

, 2013
MicroRNAs are endogenous non-coding RNA (~22nt) that bind to the 3\u27 untranslated region (UTR) of target messenger RNA (mRNA) and facilitate translational repression and degradation.
Heair, Hannah Maria
core  

Inositol-requiring enzyme 1 alpha is essential for dentinogenesis

Frontiers in Physiology
IntroductionInositol-requiring enzyme 1 alpha (IRE1α), encoded by endoplasmic reticulum (ER) to nucleus signaling 1 (Ern1) gene, is the most conserved sensor of ER stress.
Qian Xu, Qian Xu, Tian Liang, Tian Liang, Jiahe Li, Suzhen Wang, Hua Zhang, Julie Hollien, Takao Iwawaki, Chunlin Qin, Yongbo Lu   +10 more
doaj   +1 more source

Ca2+ Channels in Odontoblasts

Journal of Oral Biosciences, 2010
Abstract Odontoblasts, well-polarized columnar cells at the periphery of the dental pulp, originate from neural crest cells. They are primarily involved in dentin formation (dentinogenesis) as sites of the synthesis and secretion of collagenous and non-collagenous matrix proteins, and also participate in the directional transport of Ca 2+ from the ...
Shibukawa, Yoshiyuki, Tsumura, Maki, Sato, Masaki, Ichikawa, Hideki, Momose, Yasunori, Tazaki, Masakazu   +5 more
openaire   +1 more source

Modeling the Histogenetic Switch Between Enameloid and Enamel

Evolution &Development, Volume 28, Issue 3, September 2026.
This evo–devo exploration of ~550,000 histogenetic simulations forming dentine, enameloid, and enamel identifies 38 independent ways to induce the enameloid–enamel transition, with delayed matrix vesicle secretion (SVO‐) emerging as the key modification, providing new insights into the origin of enamel in early osteichthyans.
Guillaume Houée, Jérémie Bardin, Damien Germain, Nicolas Goudemand   +3 more
wiley   +1 more source

Dentine Regeneration With Calcium Strontium Silicate: In Vitro Odontogenic Differentiation, Antimicrobial Activity, Immunomodulation and In Vivo Pulpotomy in Rat Molars

International Endodontic Journal, Volume 59, Issue 9, Page 1871-1886, September 2026.
ABSTRACT Aim This study examined the in vitro and in vivo performance of calcium strontium silicate (CSR) as a novel biomaterial for vital pulp therapy (VPT), assessing its odontogenic differentiation, antibacterial activity, immunomodulation, inflammatory response and dentine regeneration potential compared to calcium silicate (CS) and Mineral ...
Mohamed Mahmoud Abdalla, Vidhyashree Rajasekar, Heba Ahmed, Mengyu Huang, Cynthia Kar Yung Yiu   +4 more
wiley   +1 more source

Inflammation‐Regeneration Axis of Dental Pulp Stem Cells: Wnt/NF‐κB Crosstalk

International Endodontic Journal, Volume 59, Issue 9, Page 1743-1759, September 2026.
ABSTRACT Background Inflammation critically determines dental pulp regenerative outcomes, with dental pulp stem cells (DPSCs) orchestrating tissue homeostasis through differentiation, self‐renewal and immunomodulation processes dynamically regulated by Wnt/β‐catenin and NF‐κB signaling crosstalk.
V. Rajasekar, M. Huang, M. M. Abdalla, P. Neelakantan, C. K. Y. Yiu   +4 more
wiley   +1 more source

Odontoblast-szerű sejtek mechanosensitiv tulajdonságainak vizsgálata in vitro

Bevezetés: A mai napig nem teljesen tisztázott a fogfájdalom pontos pathofiziológiai mechanizmusa. Több hipotézis is létezik, melyek közül az úgynevezett hidrodinamikai elmélet, mely szerint a fogakat kívülről érő fizikai ingereket a dentintubulusokban ...
Boda, Zsolt Dénes
core  

Some factors affecting the bioassay of vitamin C by the odontoblast method.

, 1946
Experiments were carried out to determine the effect of factors, other than vitamin C, on the development of odontoblast cells in the guinea pig incisor tooth.
Burton, Barbara W.
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