Results 81 to 90 of about 7,290 (223)

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

Understanding extracellular vesicle biology, isolation, and characterization: The theory of EV‐erything

Periodontology 2000, EarlyView.
Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad, Nima Farshidfar, Nathan E. Estrin, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +6 more
wiley   +1 more source

LincRNA-ASAO promotes dental pulp repair through interacting with PTBP1 to increase ALPL alternative splicing

Stem Cell Research & Therapy
Background Alternative splicing not only expands the genetic encoding of genes but also determines cellular activities. This study aimed to elucidate the regulation mechanism and biological functions of lincRNA-ASAO in the process of odontogenesis ...
Fuchun Fang, Xiaolan Guo, Sitong Liu, Longrui Dang, Zehao Chen, Yumeng Yang, Lu Chen, Jiahao Lin, Wei Qiu, Zhao Chen, Buling Wu   +10 more
doaj   +1 more source

The Role of Neuropeptide Y in Dental Pulp: Balancing Neurogenic Inflammation and Pain Modulation

International Endodontic Journal, Volume 59, Issue 10, Page 2028-2045, October 2026.
ABSTRACT Background Dental pulp is a densely innervated, low‐compliance tissue in which neurogenic inflammation can rapidly escalate into oedema, raised intrapulpal pressure, microvascular compromise, and pain. While Substance P (SP) and Calcitonin gene‐related peptide (CGRP) are well‐established drivers of pulp vasodilation, the Neuroopeptide Y (NPY ...
Javier Caviedes‐Bucheli, Esteban Ulate, Hugo‐Roberto Munoz, Nestor Ríos‐Osorio   +3 more
wiley   +1 more source

Potassium Currents Activated by Depolarization in Odontoblasts

Frontiers in Physiology, 2017
Increased intracellular free Ca2+ concentrations elicit plasma membrane depolarization, which leads to the activation of K+ currents. However, the precise properties of K+ currents activated by depolarization in odontoblasts remain to be elucidated.
Yuki Kojima, Maki Kimura, Asuka Higashikawa, Kyosuke Kono, Masayuki Ando, Masakzu Tazaki, Yoshiyuki Shibukawa   +6 more
doaj   +1 more source

Nucleic Acids as Emerging Regulators of Calcium Phosphate Biomineralization

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
Calcium phosphate biomineralization has traditionally been considered a protein‐regulated process. This review highlights the emerging role of nucleic acids, which interact with mineral phases through adsorption, coprecipitation, and templating, thereby influencing crystal nucleation and growth.
Fanny Duhalde, Jessem Landoulsi, Xavier Houard   +2 more
wiley   +1 more source

Constitutive expression of spliced X-box binding protein 1 inhibits dentin formation in mice

Frontiers in Physiology
Upon endoplasmic reticulum (ER) stress, inositol-requiring enzyme 1 (IRE1) is activated, which subsequently converts an unspliced X-box binding protein 1 (XBP1U) mRNA to a spliced mRNA that encodes a potent XBP1S transcription factor.
Qian Xu, Jiahe Li, Hua Zhang, Suzhen Wang, Chunlin Qin, Yongbo Lu   +5 more
doaj   +1 more source

A Histological Study on Venom Apparatus of Montivipera xanthina (Gray, 1849) (Serpentes, Viperidae)

Brazilian Archives of Biology and Technology, 2016
This is the first report describing morphological and histological structure of venom apparatus in Montivipera xanthina. The venom gland apparatus of M.
Dilara Çolak Kılıç, Esra Akat, Hüseyin Arıkan   +2 more
doaj   +1 more source

New technologies in oral reconstructive medicine: Consensus report of the AAP/OF/SEPA Workshop

Journal of Periodontology, Volume 97, Issue S1, Page S8-S32, September 2026.
Abstract Background The objectives of this Workshop were to evaluate the efficacy of scaffolding technologies for horizontal and vertical ridge augmentation; to evaluate the efficacy of substitute scaffolds for soft tissue augmentation in the context of implant therapy; to evaluate the efficacy of cells and/or biologics combined with scaffolds for ...
Mariano Sanz, Sašo Ivanovski, José Nart, Frank Schwarz, Hom‐Lay Wang, Tara L. Aghaloo, Bilal Al‐Nawas, Gustavo Avila‐Ortiz, Shayan Barootchi, Juan Blanco, Gonzalo Blasi, Nikolaos Donos, Balazs Feher, Irina F. Dragan, Maria L. Geisinger, Adrián Guerrero, Effie Ioannidou, Darnell Kaigler, Yvonne Hernandez‐Kapila, Purnima S. Kumar, Liran Levin, Antonio Liñares, George A. Mandelaris, Paula Matesanz‐Pérez, Alberto Monje, Eduardo Montero, Alberto Ortiz‐Vigón, Joan Otomo‐Corgel, Flavia Q. Pirih, Ausra Ramanauskaite, Isabella Rocchietta, Vanessa Ruiz‐Magaz, Hanae Saito, Nerea Sánchez, Javier Sanz Esporrin, Anton Sculean, Florian M. Thieringer, Daniel S. Thoma, Cristina Valles, Diego Velásquez, David T. Wu, William V. Giannobile   +41 more
wiley   +1 more source

Histomorphometric analysis of odontoblast-like cell numbers and dentine bridge secretory activity following pulp exposure

, 2003
AIM: The purpose of this study was to collect quantitative information about the numbers and dentine bridge secretory activity of odontoblast-like cells following dental pulp exposure.
Murray, PE, Windsor, LJ, Hafez, AA, Cox, CF, Smith, Anthony   +4 more
core   +1 more source