Results 81 to 90 of about 6,585 (238)

Constitutive expression of spliced X-box binding protein 1 inhibits dentin formation in mice

Frontiers in Physiology
Upon endoplasmic reticulum (ER) stress, inositol-requiring enzyme 1 (IRE1) is activated, which subsequently converts an unspliced X-box binding protein 1 (XBP1U) mRNA to a spliced mRNA that encodes a potent XBP1S transcription factor.
Qian Xu, Jiahe Li, Hua Zhang, Suzhen Wang, Chunlin Qin, Yongbo Lu   +5 more
doaj   +1 more source

A Histological Study on Venom Apparatus of Montivipera xanthina (Gray, 1849) (Serpentes, Viperidae)

Brazilian Archives of Biology and Technology, 2016
This is the first report describing morphological and histological structure of venom apparatus in Montivipera xanthina. The venom gland apparatus of M.
Dilara Çolak Kılıç, Esra Akat, Hüseyin Arıkan   +2 more
doaj   +1 more source

Molecular Basis and Clinical Spectrum of WNT10A‐Related Oligodontia

Clinical Genetics, Volume 110, Issue 1, Page 3-14, July 2026.
Cellular Mechanism behind WNT10A phenotypes. ABSTRACT WNT10A mutations, a major genetic determinant of dental agenesis and ectodermal dysplasia, exert profound effects on craniofacial development. Although classified as rare disorders, these mutations account for more than half of oligodontia cases, reflecting their critical role.
Perennes Elise, Benkirane‐Jessel Nadia, Anton Nicolas, Vandamme Thierry, Clauss François, Conzatti Guillaume   +5 more
wiley   +1 more source

Towards Regenerative Dentistry: Human iOB Differentiation Guided by Single Cell Transcriptomic Atlas of Human Developing Odontoblast.

, 2022
Thesis (Ph.D.)--University of Washington, 2022University of WashingtonABSTRACT Towards Regenerative Dentistry: Human iOB Differentiation Guided by Single Cell Transcriptomic Atlas of Human Developing Odontoblast.
Hanson-Drury, Sesha
core  

Molecular Signatures of Peripheral and Central Dental Pulp Subpopulations in Response to Streptococcus mutans: A Bulk RNA‐Seq Analysis

International Endodontic Journal, Volume 59, Issue 7, Page 1402-1415, July 2026.
ABSTRACT Aim The dental pulp is an immunologically active tissue that responds dynamically to cariogenic challenge. Peripheral pulp cells adjacent to dentine encounter bacterial stimuli earlier than cells located in the central pulp. To investigate signalling and immune interactions, this study profiled the transcriptomes of dentine‐adherent cells ...
Sandra Pohl, Maximilian L. Huber, Tobias Akamp, Andreas Rosendahl, Melanie Linnebank, Lea Schreiber, Claudia Gebhard, Nicholas Strieder, Michael Rehli, Wolfgang Buchalla, Matthias Widbiller   +10 more
wiley   +1 more source

Inositol-requiring enzyme 1 alpha is essential for dentinogenesis

Frontiers in Physiology
IntroductionInositol-requiring enzyme 1 alpha (IRE1α), encoded by endoplasmic reticulum (ER) to nucleus signaling 1 (Ern1) gene, is the most conserved sensor of ER stress.
Qian Xu, Qian Xu, Tian Liang, Tian Liang, Jiahe Li, Suzhen Wang, Hua Zhang, Julie Hollien, Takao Iwawaki, Chunlin Qin, Yongbo Lu   +10 more
doaj   +1 more source

Deep Caries Management: EFCD‐ESE‐ORCA S3‐Level Clinical Practice Guideline

International Endodontic Journal, Volume 59, Issue 7, Page 1298-1315, July 2026.
ABSTRACT Objective To develop an evidence‐based S3‐level clinical practice guideline for the management of deep and extremely deep caries in vital permanent teeth. Methods An evidence‐based medical guideline based on systematically searched and appraised evidence as well as a structured consensus (S3‐level) was jointly developed by the European ...
Falk Schwendicke, Esra Kosan, Avijit Banerjee, Aylin Baysan, Lars Bjørndal, Laura Ceballos, Henry F. Duncan, Sascha Herbst, Klaus W. Neuhaus, Anne C. O'Connell, Sebastian Paris, Helena Dujic   +11 more
wiley   +1 more source

Diagnostic Accuracy of Dentin Sclerosis by Optical Coherence Tomography and the North Carolina Index in Noncarious Cervical Lesions

Journal of Esthetic and Restorative Dentistry, Volume 38, Issue 7, Page 1435-1447, July 2026.
ABSTRACT Objective To evaluate the diagnostic accuracy of optical coherence tomography (OCT) and the North Carolina Index (NCI) for identifying dentin type (sclerotic vs. nonsclerotic) in natural noncarious cervical lesions (NCCLs). Materials and Methods Thirty extracted human premolars with 30 NCCLs (90 regions of interest) were analyzed. Two blinded,
Nathalie Murielly Rolim de Abreu, Rudyard dos Santos Oliveira, Anauara Lima e Silva, Laryssa Mylenna Madruga Barbosa, Alessandro Dourado Loguercio, Frederico Barbosa de Sousa   +5 more
wiley   +1 more source

TWIST1 Promotes the Odontoblast-like Differentiation of Dental Stem Cells [PDF]

, 2011
Stem cells derived from the dental pulp of extracted human third molars (DPSCs) have the potential to differentiate into odontoblasts, osteoblasts, adipocytes, and neural cells when provided with the appropriate conditions.
I. Maciejewska, Y. Li, K.M. Galler, Cavender, A., Galler, Kerstin M., Lu, Y., D’Souza, R. N., A. Cavender, Li, Y., R.N. D’Souza, Maciejewska, I., Y. Lu   +11 more
core   +1 more source

DEPTH DEPENDENT HEAT RESPONSE ON ODONTOBLAST LAYER: COMPARISON OF HIGH SPEED HAND-PIECE DIAMOND VERSUS CARBIDE BURS

Pakistan Armed Forces Medical Journal, 2020
Objective: To find out the depth dependent heat effect of Diamond and Carbide burs on odontoblast layer and processes of premolar teeth. Study Design: Laboratory based experimental study.
Nabila Momin, Zilli Huma, Muhammad Haroon, Najma Baseer   +3 more
doaj