Results 61 to 70 of about 6,585 (238)

The Role of Neuropeptide Y in Dental Pulp: Balancing Neurogenic Inflammation and Pain Modulation

International Endodontic Journal, EarlyView.
ABSTRACT Background Dental pulp is a densely innervated, low‐compliance tissue in which neurogenic inflammation can rapidly escalate into oedema, raised intrapulpal pressure, microvascular compromise, and pain. While Substance P (SP) and Calcitonin gene‐related peptide (CGRP) are well‐established drivers of pulp vasodilation, the Neuroopeptide Y (NPY ...
Javier Caviedes‐Bucheli, Esteban Ulate, Hugo‐Roberto Munoz, Nestor Ríos‐Osorio   +3 more
wiley   +1 more source

VEGF and odontoblast-like cells: stimulation by low frequency ultrasound

, 2009
OBJECTIVE: Vascular endothelial growth factor (VEGF) has been implicated in the regulation of dental pulp and dentine repair. Therapeutic ultrasound was shown to be effective for fracture repair.
Man, J, Millard, Jane, Scheven, Ben, Lea, Simon, Walmsley, Anthony; id_orcid, Cooper, Paul, Smith, Anthony   +6 more
core   +1 more source

Tubule and microbranch variations in human dentine: A quantitative 3D study with serial block‐face scanning electron microscopy

Journal of Microscopy, EarlyView.
ABSTRACT Objective: Microbranches exist within dentine, providing a network of fluid filled connections between tubules. This study used serial block‐face scanning electron microscopy to generate 3D volumes of dentine from different tooth locations, allowing for investigations of the microbranch morphology, the microbranch network characteristics and ...
Bethany Harding, Patricia Goggin, James Thompson, Behrad Mahmoodi, Katy Rankin, Philipp Schneider, Richard Cook   +6 more
wiley   +1 more source

Histological analysis of incremental markings and crown growth characteristics in mandibular first molars of the red fox, Vulpes vulpes (Canidae, Mammalia)

Journal of Anatomy, EarlyView.
This paper histologically analyzed incremental markings in dental enamel of red fox and grey wolf. Our results demonstrate that previous studies have misidentified these markings, which led to miscalculation of dental growth parameters. Abstract The present study analyzed incremental markings in the enamel of eight mandibular first molars (M1) of red ...
Horst Kierdorf, Uwe Kierdorf
wiley   +1 more source

Interpretation of the concepts of dentinal tubule and dentinal canaliculus

Regulatory Mechanisms in Biosystems
The biology of dentin occupies a central place in the theory of tooth integrity as an organ, and knowledge about the microstructure of dentin changes with the development of new research methods, such as scanning electron microscopy.
S. L. Popel, N. O. Gevkaliuk, N. I. Sydliaruk, Y. M. Martyts, M. Y. Pynda, V. Y. Pudyak, V. Y. Krupey   +6 more
doaj   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Expression of nerve growth factor (NGF), TrkA and p75NTR in developing human foetal teeth

Frontiers in Physiology, 2016
Nerve growth factor (NGF) is important for the development and the differentiation of neuronal and non-neuronal cells. NGF binds to specific low- and high-affinity cell surface receptors, respectively p75NTR and TrkA. In the present study, we examined by
Thimios A. Mitsiadis, Pierfrancesco Pagella   +1 more
doaj   +1 more source

Localized Periodontitis in Young Individuals: Aggregatibacter JP2 Clone, Immunological Dysfunctions and Other Stories

Journal of Periodontal Research, EarlyView.
This review describes the features of grade C molar‐incisor pattern periodontitis and discusses the role of A. actinomycetemcomitans in its pathogenesis and why molars and incisors are preferably affected. Possible future studies on this aggressive disease in primary and permanent dentition and emerging omics techniques for diagnosis and management are
Luigi Nibali, Meaad M. Alamri, Manuela Maria Viana Miguel, Luciana Shaddox   +3 more
wiley   +1 more source

Human odontoblast-like cells produce nitric oxide with antibacterial activity upon TLR2 activation

Frontiers in Physiology, 2015
The penetration of cariogenic oral bacteria into enamel and dentin during the caries process triggers an immune/inflammatory response in the underlying pulp tissue, the reduction of which is considered a prerequisite to dentinogenesis-based pulp ...
Jean-Christophe eFARGES, Jean-Christophe eFARGES, Jean-Christophe eFARGES, Jean-Christophe eFARGES, Aurélie eBellanger, Maxime eDucret, Maxime eDucret, Maxime eDucret, Elisabeth eAubert-Foucher, Beatrice eRichard, Beatrice eRichard, Beatrice eRichard, Brigitte eAlliot-licht, Françoise eBleicher, Florence eCarrouel, Florence eCarrouel   +15 more
doaj   +1 more source

The Effects of Rapid Periodontal Distraction on Tooth Vitality and Bone Quality/Quantity: A Split‐Mouth Experimental Design

Orthodontics &Craniofacial Research, EarlyView.
ABSTRACT Objectives Periodontal distraction (PD) osteogenesis is a minimally invasive technique capable of rapidly moving uniradicular teeth, thereby shortening orthodontic treatment time. This study aimed to determine whether: (1) PD‐induced tooth movement affects tooth vitality and (2) the regenerated bone meets restorative standards for implant ...
Parul Sangwan, Ying Liu, Phillip M. Campbell, Michael Ellis, Yan Jing, Peter H. Buschang   +5 more
wiley   +1 more source