Results 41 to 50 of about 6,585 (238)

Lithium Chloride Exerts Differential Effects on Dentinogenesis and Osteogenesis in Primary Pulp Cultures

Frontiers in Dental Medicine, 2021
Wnt/β-catenin signaling is known to play essential roles in odontoblast differentiation and reparative dentin formation. Various Wnt activators including LiCl have been increasingly studied for their effectiveness to induce repair of the dentin-pulp ...
Anushree Vijaykumar, Mina Mina
doaj   +1 more source

Ultrastructure of Capillaries in the Odontoblastic Layer [PDF]

Journal of Dental Research, 1973
Peer Reviewed ; http://deepblue.lib.umich.edu/bitstream/2027.42/66558/2/10.1177_00220345730520024101 ...
Corpron, R. E., Avery, James K., Lee, Soo D.   +2 more
openaire   +3 more sources

Single‐Cell Virtual Perturbation Screening Identifies STAT3 as a Key Regulator of Dentinogenesis

Cell Proliferation, EarlyView.
STAT3 promotes odontoblast differentiation in dental mesenchymal cells by transcriptionally regulating WNT2B via the canonical Wnt/β‐catenin signalling pathway. These findings elucidate a mechanism underlying dentine development. ABSTRACT Dentine formation constitutes a physiological process precisely regulated by signal transduction modules governing ...
Yanfei Zhu, Hongyuan Xu, Zijian Zhang, Siyuan Sun, Zihan Huang, Xin Gao, Houwen Pan, Xiangru Huang, Yuanqi Liu, Xinyu Wang, Hanbin Jia, Qinggang Dai, Lingyong Jiang   +12 more
wiley   +1 more source

Ultrastructural and biochemical analysis of in vitro odontoblast diff erentiation

, 2011
The purpose of this study was to develop an in vitro model of odontoblast differentiation and dentin formation which allows to deeply and better study the process of odontoblast differentiation and protein matrix deposition and mineralization.
Teti Gabriella, Trirè, Alessandra, PELOTTI, SUSI, Alessandra Trirè, Gabriella, Teti, SALVATORE, VIVIANA, FALCONI, MIRELLA   +6 more
core   +1 more source

Single cell RNA sequencing reveals human tooth type identity and guides in vitro hiPSC derived odontoblast differentiation (iOB)

Frontiers in Dental Medicine, 2023
Over 90% of the U.S. adult population suffers from tooth structure loss due to caries. Most of the mineralized tooth structure is composed of dentin, a material produced and mineralized by ectomesenchyme derived cells known as odontoblasts.
Sesha Hanson-Drury, Sesha Hanson-Drury, Sesha Hanson-Drury, Anjali P. Patni, Anjali P. Patni, Anjali P. Patni, Anjali P. Patni, Deborah L. Lee, Deborah L. Lee, Deborah L. Lee, Ammar Alghadeer, Ammar Alghadeer, Ammar Alghadeer, Ammar Alghadeer, Yan Ting Zhao, Yan Ting Zhao, Yan Ting Zhao, Devon Duron Ehnes, Devon Duron Ehnes, Devon Duron Ehnes, Vivian N. Vo, Vivian N. Vo, Vivian N. Vo, Sydney Y. Kim, Sydney Y. Kim, Druthi Jithendra, Druthi Jithendra, Ashish Phal, Ashish Phal, Ashish Phal, Natasha I. Edman, Natasha I. Edman, Natasha I. Edman, Natasha I. Edman, Thomas Schlichthaerle, Thomas Schlichthaerle, David Baker, David Baker, David Baker, Jessica E. Young, Jessica E. Young, Julie Mathieu, Julie Mathieu, Hannele Ruohola-Baker, Hannele Ruohola-Baker, Hannele Ruohola-Baker, Hannele Ruohola-Baker, Hannele Ruohola-Baker   +47 more
doaj   +1 more source

Mutant DLX 3 disrupts odontoblast polarization and dentin formation

, 2010
Tricho-dento-osseous (TDO) syndrome is an autosomal dominant disorder characterized by abnormalities in the thickness and density of bones and teeth. A 4-bp deletion mutation in the Distal-Less 3 (DLX3) gene is etiologic for most cases of TDO.
T. Gao, Haruyama, N., Robey, P.G., Choi, S.J., N. Haruyama, J.Q. Feng, Thomas C. Hart, Song, I.S., P. Gautam, Gao, T., Gautam, P., S.J. Choi, Hart, Thomas C., I.S. Song, P.G. Robey, Feng, J.Q.   +15 more
core   +1 more source

Establishment of an MRI‐Based Diagnostic Approach to Identify Critical Pulpal Inflammation Zones in a Rat Caries‐Derived Pulpitis Model

International Endodontic Journal, EarlyView.
ABSTRACT Aim To establish a magnetic resonance imaging (MRI)‐based diagnostic approach for identifying ‘critical pulpal inflammation’ zones in a rat model of caries‐derived pulpitis. Methodology Caries‐derived pulpitis was induced in the molars of Sprague–Dawley rats using the caries‐derived pulpitis model.
Kiichi Moriyama, Motoki Okamoto, Masakatsu Watanabe, Hailing Huang, Koki Nakatani, Shigeyoshi Saito, Yusuke Takahashi, Mikako Hayashi   +7 more
wiley   +1 more source

Neuro-odontoblast interactions

, 2007
To study the close relationship between odontoblasts and intradental nerves in order to elucidate its role in the sensory mechanism that is responsible for dentinal pain.
De Peralta, Tracy, Raab, Wolfgang Hans-Michael, VANDENABEELE, Frank, STRUYS, Tom, Schepers, Serge, POLITIS, Constantinus, LAMBRICHTS, Ivo   +6 more
core   +1 more source

Novel Roles of Nestin in Postnatal Root Formation

Dentistry Journal
Background/Objectives: Nestin is an intermediate filament protein and a marker of odontoblasts, but its function in tooth and bone formation is largely unknown.
Yan Jing, Jinqiu Wu, Ying Liu, Xiaohua Liu, Chi Ma   +4 more
doaj   +1 more source

Dentine Regeneration With Calcium Strontium Silicate: In Vitro Odontogenic Differentiation, Antimicrobial Activity, Immunomodulation and In Vivo Pulpotomy in Rat Molars

International Endodontic Journal, EarlyView.
ABSTRACT Aim This study examined the in vitro and in vivo performance of calcium strontium silicate (CSR) as a novel biomaterial for vital pulp therapy (VPT), assessing its odontogenic differentiation, antibacterial activity, immunomodulation, inflammatory response and dentine regeneration potential compared to calcium silicate (CS) and Mineral ...
Mohamed Mahmoud Abdalla, Vidhyashree Rajasekar, Heba Ahmed, Mengyu Huang, Cynthia Kar Yung Yiu   +4 more
wiley   +1 more source