Results 21 to 30 of about 6,585 (238)

Odontogenic Differentiation-Induced Tooth Regeneration by Psoralea corylifolia L.

Current Issues in Molecular Biology, 2022
Psoralea corylifolia L. (P. corylifolia) has been used as an oriental phytomedicine to treat coldness of hands and feet in bone marrow injury. Hydroxyapatite is usually used for tooth regeneration. In this study, the role of P. corylifolia and bakuchiol,
Hye-Ock Jang, Tea-Young Ahn, Ji-Min Ju, Soo-Kyung Bae, Hyung-Ryong Kim, Da-Sol Kim   +5 more
doaj   +1 more source

In vitro reparative dentin: a biochemical and morphological study

European Journal of Histochemistry, 2013
In this study, starting from human dental pulp cells cultured in vitro, we simulated reparative dentinogenesis using a medium supplemented with different odontogenic inductors.
G. Teti, V. Salvatore, A. Ruggeri, L. Manzoli, M. Gesi, G. Orsini, M. Falconi   +6 more
doaj   +1 more source

Isolation and Differentiation of Adipose-Derived Stem Cells into Odontoblast-Like Cells: A Preliminary In Vitro Study [PDF]

, 2021
Objective: The aim of present study was to isolate and differentiate human adipose-derived stem cells (ASCs) into odontoblast-like cells. Materials and Methods: In this experimental study, human adipose tissues were taken from the buccal fat pad of ...
Abbasali Khademi, Khazaei, M., Paul M. H. Dummer, Khazaei, Saber, Mohammad Hossein Nasr Esfahani, Dummer, Paul MH, Khademi, A., Mozafar Khazaei, Nekoofar, M. H., Khazaei, Mozafar, Dummer, P. M. H., Khademi, Abbasali, Nekoofar, Mohammad Hossein, Mohammad Hossein Nekoofar, Nasr Esfahani, Mohammad Hossein, Saber Khazaei, Khazaei, S., Esfahani, M. H. N.   +17 more
core   +1 more source

Cytocompatibility and Bioactive Ion Release Profiles of Phosphoserine Bone Adhesive: Bridge from In Vitro to In Vivo

Biomedicines, 2022
One major challenge when developing new biomaterials is translating in vitro testing to in vivo models. We have recently shown that a single formulation of a bone tissue adhesive, phosphoserine modified cement (PMC), is safe and resorbable in vivo ...
Kateřina Vrchovecká, Monika Pávková-Goldbergová, Håkan Engqvist, Michael Pujari-Palmer   +3 more
doaj   +1 more source

Mitochondrial DNA leakage exacerbates odontoblast inflammation through gasdermin D-mediated pyroptosis

Cell Death Discovery, 2021
Alleviating odontoblast inflammation is crucial to control the progression of pulpitis. Mitochondrial DNA (mtDNA) is a vital driver of inflammation when it leaks from mitochondria of inflamed odontoblasts into the cytosol.
Yi-Fei Zhang, Lu Zhou, Han-Qing Mao, Fu-Hua Yang, Zhi Chen, Lu Zhang   +5 more
doaj   +1 more source

Yap-Regulated Er Stress Promotes Dentin Formation And Odontoblast Differentiation

International Dental Journal
Aim or purpose: This study aimed to investigate whether endoplasmic reticulum (ER) stress mediated by Yes-associated protein (YAP) plays a role during dentin formation and odontoblast differentiation in dental pulp stem cells (DPSCs).
Yu Du, Zhiqing Xu
doaj   +1 more source

Expression and function of dopamine in odontoblasts [PDF]

Journal of Cellular Physiology, 2019
AbstractDopamine (DA) is produced from tyrosine by tyrosine hydroxylase (TH). A recent study has reported that DA promotes the mineralization of murine preosteoblasts. However, the role of DA in odontoblasts has not been examined. Therefore, in this investigation, we researched the expression of TH and DA in odontoblasts and the effects of DA on the ...
Shoko Fujino, Sayuri Hamano, Atsushi Tomokiyo, Tomohiro Itoyama, Daigaku Hasegawa, Hideki Sugii, Shinichiro Yoshida, Ayako Washio, Aoi Nozu, Taiga Ono, Naohisa Wada, Chiaki Kitamura, Hidefumi Maeda   +12 more
openaire   +2 more sources

Different concentrations of C5a affect human dental pulp mesenchymal stem cells differentiation

BMC Oral Health, 2021
Background During the process of deep decay, when decay approaches the pulp, an immune response is triggered inside the pulp, which activates the complement cascade.
Jie Liu, Xiaoling Wei, Junlong Hu, Xiaohan Tan, Xiaocui Kang, Li Gao, Ning Li, Xin Shi, Mengtong Yuan, Weiping Hu, Mingyue Liu   +10 more
doaj   +1 more source

Role of the Demethylase AlkB Homolog H5 in the Promotion of Dentinogenesis

Frontiers in Physiology, 2022
Dentinogenesis is a key process in tooth formation and is regulated by a series of pre- and post-transcriptional regulations. N6-methyl-adenosine (m6A), which is the most prevalent internal chemical modification that can be removed by the RNA demethylase
Cheng Tian, Jihua Chai, Weidong Liu, Xinye Zhang, Yashu Li, Huanyan Zuo, Guohua Yuan, Haojian Zhang, Haojian Zhang, Huan Liu, Huan Liu, Zhi Chen, Zhi Chen   +12 more
doaj   +1 more source

The Critical Role of MMP13 in Regulating Tooth Development and Reactionary Dentinogenesis Repair Through the Wnt Signaling Pathway

Frontiers in Cell and Developmental Biology, 2022
Matrix-metalloproteinase-13 (MMP13) is important for bone formation and remodeling; however, its role in tooth development remains unknown. To investigate this, MMP13-knockout (Mmp13−/−) mice were used to analyze phenotypic changes in the dentin–pulp ...
Henry F. Duncan, Yoshifumi Kobayashi, Yukako Yamauchi, Angela Quispe-Salcedo, Zhi Chao Feng, Jia Huang, Nicola C. Partridge, Teruyo Nakatani, Jeanine D’Armiento, Emi Shimizu   +9 more
doaj   +1 more source