Results 11 to 20 of about 7,457 (217)

Identification of dentinogenic cell-specific surface antigens in odontoblast-like cells derived from adult dental pulp

Stem Cell Research & Therapy, 2019
Background Odontoblast is a unique progenitor that plays a role in dentin formation. So far, the dentinogenic differentiation of dental pulp stem cells and the role of surface molecules of odontoblasts in dentinogenesis are not well known yet.
Kyung-Jung Kang, Chun-Jeih Ryu, Young-Joo Jang   +2 more
doaj   +2 more sources

Odontoblast commitment and differentiation

Biochemistry and Cell Biology, 1998
Histological and cytological organization confer specificity to the odontoblasts. These postmitotic, neural crest derived, polarized cells are aligned in a single layer at the periphery of the dental pulp and secrete the organic components of predentin ...
Jean Victor Ruch
core   +3 more sources

Increasing Odontoblast-like Differentiation from Dental Pulp Stem Cells through Increase of β-Catenin/p-GSK-3β Expression by Low-Frequency Electromagnetic Field

Biomedicines, 2021
Odontoblasts produce proteins that form the dentinal extracellular matrix, which can protect the dental pulp from external stimuli and is required for tooth regeneration.
Han-Moi Lim, Myeong-Hyun Nam, Yu-Mi Kim, Young-Kwon Seo   +3 more
doaj   +2 more sources

Mild heat stress promotes the differentiation of odontoblast-like MDPC-23 cells via yes-associated protein

International Journal of Hyperthermia
Purpose Dentin hypersensitivity (DH) is a prevalent condition, but long-term effective treatments are scarce. Differentiation of odontoblast-like cells is promising for inducing tertiary dentinogenesis and ensuring sustained therapeutic efficacy against ...
Peiqi Liu, Zhen Li, Hui Zhang, Yijie Wang, Yuxin Liao, Yi Guo, Chenxu Wang, Yuanwu Zou, Rui Zou, Lin Niu   +9 more
doaj   +2 more sources

The Enhancing Effects of Amelogenin Exon 5-Encoded Peptide from Enamel Matrix Derivative on Odontoblast-Like KN-3 Cells

Applied Sciences, 2018
Enamel matrix derivative (EMD) is applied for periodontal therapy. We created a synthetic amelogenin peptide (SP) derived from EMD, and have previously investigated the biological function of SP.
Hirohito Kato, Yoichiro Taguchi, Kazutaka Imai, Yaru Ruan, Yu-Wei Tsai, Yi-Chie Chen, Muneyasu Shida, Reiko Taguchi, Kazuya Tominaga, Makoto Umeda   +9 more
doaj   +3 more sources

Chromatin Remodeller BRD9 Orchestrates Odontoblastic Differentiation via Coordinating RUNX2-KLF4. [PDF]

Cell Prolif
During odontoblast lineage commitment, the chromatin remodeller BRD9 acts as a critical epigenetic coordinator, orchestrating the chromatin landscape to facilitate synergistic binding of key transcription factors RUNX2 and KLF4 to target loci for odontogenesis.
Zeng W, Lin Y, Gao Y, Huang D, Li Y, Ruan H, Yuan G, Liu H, Chen Z.   +8 more
europepmc   +2 more sources

Natural Bioactive Epigallocatechin-Gallate Promote Bond Strength and Differentiation of Odontoblast-like Cells [PDF]

, 2023
The (-)-Epigallocatechin-gallate (EGCG) metabolite is a natural polyphenol derived from green tea and is associated with antioxidant, biocompatible, and anti-inflammatory effects. Objective: To evaluate the effects of EGCG to promote the odontoblast-like
Hamid Nurrohman, Kelvin I. Afrashtehfar, Afrashtehfar, Kelvin I., Rene Garcia-Contreras, Afrashtehfar, Kelvin I, Carlos Alberto Jurado, Nurrohman, Hamid, Garcia-Contreras, Rene, Benjamin Aranda-Herrera, Patricia Alejandra Chavez-Granados, Jurado, Carlos Alberto, Chavez-Granados, Patricia Alejandra, Aranda-Herrera, Benjamin   +12 more
core   +2 more sources

Cellular Dynamics and Dentine Bridge Formation Following Direct Pulp Capping With MTA and Biodentine in a Murine Model. [PDF]

Int Endod J
ABSTRACT Aim Formation of a mineralized dentine bridge is the hallmark of successful direct pulp capping (DPC). Mineral trioxide aggregate (MTA) and Biodentine are widely used capping materials, but in vivo evidence comparing their regenerative potential remains inconclusive. This study used a controlled murine model to compare dentine bridge formation
Sajdeya A, Milgram J, Kot-Limon N, Abramovitz I, Sharir A.   +4 more
europepmc   +2 more sources

Laminin-Modified Dental Pulp Extracellular Matrix for Dental Pulp Regeneration

Frontiers in Bioengineering and Biotechnology, 2021
Native dental pulp extracellular matrix (DPEM) has proven to be an effective biomaterial for dental pulp regeneration. However, as a significant extracellular matrix glycoprotein, partial laminins were lost during the decellularization process, which ...
Jiahui Fu, Jianfeng Chen, Wenjun Li, Xiaomin Yang, Jingyan Yang, Huixin Quan, Haitao Huang, Gang Chen, Gang Chen   +8 more
doaj   +1 more source

CPNE7-Induced Autophagy Restores the Physiological Function of Mature Odontoblasts

Frontiers in Cell and Developmental Biology, 2021
Dentin, which composes most of the tooth structure, is formed by odontoblasts, long-lived post-mitotic cells maintained throughout the entire life of the tooth. In mature odontoblasts, however, cellular activity is significantly weakened.
Yeoung-Hyun Park, Yeoung-Hyun Park, Chul Son, You-Mi Seo, Yoon Seon Lee, Alix Har, Joo-Cheol Park, Joo-Cheol Park   +7 more
doaj   +1 more source