Results 11 to 20 of about 7,290 (223)

Intercellular odontoblast communication via ATP mediated by pannexin-1 channel and phospholipase C-coupled receptor activation.

Frontiers in Physiology, 2015
Extracellular ATP released via pannexin-1 channels, in response to the activation of mechanosensitive-TRP channels during odontoblast mechanical stimulation, mediates intercellular communication among odontoblasts in dental pulp slice preparation ...
Masaki eSato, Tadashi eFuruya, Tadashi eFuruya, Maki eKimura, Yuki eKojima, Masakazu eTazaki, Toru eSato, Yoshiyuki eShibukawa   +7 more
doaj   +2 more sources

Odontoblast morphology and dental repair [PDF]

Journal of Dentistry, 2003
To investigate the changes in morphology and activity of pulp odontoblasts in response to cavity restoration variables and patient factors.Class V non exposed cavities were prepared in the intact 1st or 2nd premolar teeth of 27 patients, aged between 9 and 17 years-old.
Murray, P.E., About, I., Lumley, P.J., Franquin, J.-C., Windsor, L.J., Smith, A.J.   +5 more
openaire   +3 more sources

Identification of dentinogenic cell-specific surface antigens in odontoblast-like cells derived from adult dental pulp

Stem Cell Research & Therapy, 2019
Background Odontoblast is a unique progenitor that plays a role in dentin formation. So far, the dentinogenic differentiation of dental pulp stem cells and the role of surface molecules of odontoblasts in dentinogenesis are not well known yet.
Kyung-Jung Kang, Chun-Jeih Ryu, Young-Joo Jang   +2 more
doaj   +2 more sources

FOXO3a promotes odontoblast differentiation in human dental pulp cells in coordination with RUNX2 [PDF]

Journal of Applied Oral Science
Introduction Forkhead box O3a (FOXO3a) is a stress-responsive transcription factor involved in cellular differentiation across multiple tissues.
Su-Kyung Son, Jung-Sun Moon, Na-Ri Jung, Jee-Hae Kang, Bin-Na Lee, Sun-Hun Kim, Min-Seok Kim   +6 more
doaj   +3 more sources

Mild heat stress promotes the differentiation of odontoblast-like MDPC-23 cells via yes-associated protein

International Journal of Hyperthermia
Purpose Dentin hypersensitivity (DH) is a prevalent condition, but long-term effective treatments are scarce. Differentiation of odontoblast-like cells is promising for inducing tertiary dentinogenesis and ensuring sustained therapeutic efficacy against ...
Peiqi Liu, Zhen Li, Hui Zhang, Yijie Wang, Yuxin Liao, Yi Guo, Chenxu Wang, Yuanwu Zou, Rui Zou, Lin Niu   +9 more
doaj   +2 more sources

Chromatin Remodeller BRD9 Orchestrates Odontoblastic Differentiation via Coordinating RUNX2-KLF4. [PDF]

Cell Prolif
During odontoblast lineage commitment, the chromatin remodeller BRD9 acts as a critical epigenetic coordinator, orchestrating the chromatin landscape to facilitate synergistic binding of key transcription factors RUNX2 and KLF4 to target loci for odontogenesis.
Zeng W, Lin Y, Gao Y, Huang D, Li Y, Ruan H, Yuan G, Liu H, Chen Z.   +8 more
europepmc   +2 more sources

Natural Bioactive Epigallocatechin-Gallate Promote Bond Strength and Differentiation of Odontoblast-like Cells [PDF]

, 2023
The (-)-Epigallocatechin-gallate (EGCG) metabolite is a natural polyphenol derived from green tea and is associated with antioxidant, biocompatible, and anti-inflammatory effects. Objective: To evaluate the effects of EGCG to promote the odontoblast-like
Hamid Nurrohman, Kelvin I. Afrashtehfar, Afrashtehfar, Kelvin I., Rene Garcia-Contreras, Afrashtehfar, Kelvin I, Carlos Alberto Jurado, Nurrohman, Hamid, Garcia-Contreras, Rene, Benjamin Aranda-Herrera, Patricia Alejandra Chavez-Granados, Jurado, Carlos Alberto, Chavez-Granados, Patricia Alejandra, Aranda-Herrera, Benjamin   +12 more
core   +2 more sources

Matrix metalloproteinase-3 in odontoblastic cells derived from ips cells: unique proliferation response as odontoblastic cells derived from ES cells. [PDF]

PLoS ONE, 2013
We previously reported that matrix metalloproteinase (MMP)-3 accelerates wound healing following dental pulp injury. In addition, we reported that a proinflammatory cytokine mixture (tumor necrosis factor-α, interleukin (IL)-1β and interferon-γ) induced ...
Taiki Hiyama, Nobuaki Ozeki, Makio Mogi, Hideyuki Yamaguchi, Rie Kawai, Kazuhiko Nakata, Ayami Kondo, Hiroshi Nakamura   +7 more
doaj   +1 more source

Increasing Odontoblast-like Differentiation from Dental Pulp Stem Cells through Increase of β-Catenin/p-GSK-3β Expression by Low-Frequency Electromagnetic Field

Biomedicines, 2021
Odontoblasts produce proteins that form the dentinal extracellular matrix, which can protect the dental pulp from external stimuli and is required for tooth regeneration.
Han-Moi Lim, Myeong-Hyun Nam, Yu-Mi Kim, Young-Kwon Seo   +3 more
doaj   +1 more source

CPNE7-Induced Autophagy Restores the Physiological Function of Mature Odontoblasts

Frontiers in Cell and Developmental Biology, 2021
Dentin, which composes most of the tooth structure, is formed by odontoblasts, long-lived post-mitotic cells maintained throughout the entire life of the tooth. In mature odontoblasts, however, cellular activity is significantly weakened.
Yeoung-Hyun Park, Yeoung-Hyun Park, Chul Son, You-Mi Seo, Yoon Seon Lee, Alix Har, Joo-Cheol Park, Joo-Cheol Park   +7 more
doaj   +1 more source