Defects in the acid phosphatase ACPT cause recessive hypoplastic amelogenesis imperfecta [PDF]
We identified two homozygous missense variants (c.428C>T, p.(T143M) and c.746C>T, p.(P249L)) in ACPT, the gene encoding Acid Phosphatase, Testicular, which segregate with hypoplastic Amelogenesis imperfecta (AI) in two unrelated families.
Alan J Mighell +20 more
core +1 more source
Odontoblast morphology and dental repair [PDF]
To investigate the changes in morphology and activity of pulp odontoblasts in response to cavity restoration variables and patient factors.Class V non exposed cavities were prepared in the intact 1st or 2nd premolar teeth of 27 patients, aged between 9 and 17 years-old.
Murray, P.E. +5 more
openaire +2 more sources
Pulpal and Periapical response after restoration of deep cavities in dogs' teeth with filtek silorane and filtek supreme xt systems. [PDF]
OBJECTIVE: This study evaluated, histopathologically, the pulpal and periapical response to a silorane-based resin (Filtek Silorane) and a methacrylate-based nanoparticle resin (Filtek Supreme XT) in deep cavities in dogs, having zinc oxide and eugenol ...
Gatón Hernández, Patrícia +5 more
core +1 more source
Yap-Regulated Er Stress Promotes Dentin Formation And Odontoblast Differentiation
Aim or purpose: This study aimed to investigate whether endoplasmic reticulum (ER) stress mediated by Yes-associated protein (YAP) plays a role during dentin formation and odontoblast differentiation in dental pulp stem cells (DPSCs).
Yu Du, Zhiqing Xu
doaj +1 more source
Interleukin-1β-induced autophagy-related gene 5 regulates proliferation of embryonic stem cell-derived odontoblastic cells. [PDF]
We previously established a method for the differentiation of induced pluripotent stem cells and embryonic stem cells into α2 integrin-positive odontoblast-like cells.
Nobuaki Ozeki +8 more
doaj +1 more source
Different concentrations of C5a affect human dental pulp mesenchymal stem cells differentiation
Background During the process of deep decay, when decay approaches the pulp, an immune response is triggered inside the pulp, which activates the complement cascade.
Jie Liu +10 more
doaj +1 more source
Role of the Demethylase AlkB Homolog H5 in the Promotion of Dentinogenesis
Dentinogenesis is a key process in tooth formation and is regulated by a series of pre- and post-transcriptional regulations. N6-methyl-adenosine (m6A), which is the most prevalent internal chemical modification that can be removed by the RNA demethylase
Cheng Tian +12 more
doaj +1 more source
Polarity of Mature Human Odontoblasts
Odontoblast polarization is based on histological appearance as columnar cells with asymmetric disposition of organelles and plasma membrane domains. However, little is known about the odontoblast plasma membrane organization. We investigated odontoblast membrane polarity using influenza virus hemagglutinin and vesicular stomatitis virus glycoprotein ...
Tjaderhane, L +7 more
openaire +2 more sources
Matrix-metalloproteinase-13 (MMP13) is important for bone formation and remodeling; however, its role in tooth development remains unknown. To investigate this, MMP13-knockout (Mmp13−/−) mice were used to analyze phenotypic changes in the dentin–pulp ...
Henry F. Duncan +9 more
doaj +1 more source
Analysis of the dentin-pulp complex in teeth submitted to orthodontic movement in rats [PDF]
In order to microscopically analyze the pulpal effects of orthodontic movement, 49 maxillary first molars of rats were submitted to orthodontic appliance composed of a closed coil spring anchored to the maxillary incisors, placed for the achievement of ...
CONSOLARO, Alberto +4 more
core +3 more sources

