Engineering soft-hard tissue interfaces in dental and craniofacial system by spatially controlled bioactivities. [PDF]
Jeong HJ+8 more
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Fabrication of Hard Tissue Constructs from Induced Pluripotent Stem Cells for Exploring Mechanisms of Hereditary Tooth/Skeletal Dysplasia. [PDF]
Kondo T+8 more
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The comprehensive progress of tooth regeneration from the tooth development to tissue engineering and clinical application. [PDF]
Sui Y, Zhou Z, Zhang S, Cai Z.
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KLF6-mediated glutamine metabolism governs odontogenic differentiation and matrix mineralization of dental pulp stem cells. [PDF]
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Advances in Regenerative Dentistry: A Systematic Review of Harnessing Wnt/β-Catenin in Dentin-Pulp Regeneration. [PDF]
Amir M+11 more
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S100A4 is expressed in human odontoblasts and odontoblast-like cells
Tissue and Cell, 2022The calcium-binding protein S100A4 has been found in fibroblasts in many tissues. It has been well studied in the regulating process of inflammation and tumor metastasis. However, as a calcium regulating protein, its expression in the dental pulp has not yet been elucidated.
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Fam20C overexpression in odontoblasts regulates dentin formation and odontoblast differentiation
Journal of Molecular Histology, 2023FAM20C phosphorylates secretory proteins at S-x-E/pS motifs, and previous studies of Fam20C-dificient mice revealed that FAM20C played essential roles in bone and tooth formation. Inactivation of FAM20C in mice led to hypophosphatemia that masks direct effect of FAM20C in these tissues, and consequently the direct role of FAM20C remains unknown.
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Odontoblasts in odontogenic tumors
Medical Hypotheses, 2013Odontoblasts are secretory cells displaying epithelial and mesenchymal features, which exist in a monolayer at the interface between the dentin and pulp of a tooth. During embryogenesis, these cells form a dentin shell and throughout life continue to produce dentin while, also acting as sensor cells helping to mediate tooth sensitivity. In this process,
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Mitochondria in Odontoblastic Processes [PDF]
THE odontoblastic processes of human dentin are projections of the odontoblast cytoplasm into spaces in the dense collagenous, highly mineralized dentin matrix1. These projections can be up to several mm in length resulting in the cytoplasm being a long distance (2,000–3,000µ) from the odontoblast nucleus.
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