Results 61 to 70 of about 18,767 (302)

Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis

BMEMat, EarlyView.
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang, Yuchen Li, Yunfan Zhang, Chenshuang Li, Yifan Lin, Si Chen, Bing Han   +6 more
wiley   +1 more source

BMP-2 induced Dspp transcription is mediated by Dlx3/Osx signaling pathway in odontoblasts

Scientific Reports, 2017
Dentin sialophosphoprotein (Dspp) as a differentiation marker of odontoblasts is regulated by BMP-2. However, the intimate mechanism is still unknown. Transcription factors Dlx3 and Osx are essential for odontoblasts differentiation. We hypothesized that
Guobin Yang, G. Yuan, M. MacDougall, Chen Zhi, Shuo Chen   +4 more
semanticscholar   +1 more source

Chitin scaffolds derived from the marine demosponge Aplysina fistularis stimulate the differentiation of dental pulp stem cells

Frontiers in Bioengineering and Biotechnology, 2023
The use of stem cells for tissue regeneration is a prominent trend in regenerative medicine and tissue engineering. In particular, dental pulp stem cells (DPSCs) have garnered considerable attention.
Anna Zawadzka-Knefel, Agnieszka Rusak, Monika Mrozowska, Tomasz Machałowski, Andrzej Żak, Katarzyna Haczkiewicz-Leśniak, Michał Kulus, Piotr Kuropka, Marzenna Podhorska-Okołów, Katarzyna Skośkiewicz-Malinowska   +9 more
doaj   +1 more source

Toxicity of Flow Line, Durafill VS, and Dycal to Dental Pulp Cells: Effects of Growth Factors [PDF]

, 2010
Introduction The objective was to determine the effects of growth factor treatment on dental pulp cell sensitivity to toxicity of 2 composite restoration materials, Flow Line and Durafill VS, and a calcium hydroxide pulp capping material, Dycal ...
Furey, Alyssa, Hjelmhaug, Julie, Lobner, Doug   +2 more
core   +1 more source

Odontoblasts release exosomes to regulate the odontoblastic differentiation of dental pulp stem cells

Stem Cell Research & Therapy, 2023
Abstract Background Dental pulp stem cells (DPSCs) play a crucial role in dentin-pulp complex regeneration. Further understanding of the mechanism by which DPSCs remain in a quiescent state could contribute to improvements in the dentin-pulp complex and dentinogenesis. Methods
Xinghong Luo, Weiqing Feng, Shijiang Huang, Shenghong Miao, Tao Jiang, Qian Lei, Jingyao Yin, Sheng Zhang, Xiaochun Bai, Chunbo Hao, Weizhong Li, Dandan Ma   +11 more
openaire   +3 more sources

Periodontitis treatment and microbiome in a patient with FAM20A mutation: Case study of 1.5 years

Clinical Advances in Periodontics, EarlyView.
Abstract Background Enamel‐renal‐gingival syndrome (ERGS) is an autosomal recessive disorder caused by mutations in the FAMily with sequence similarity 20A (FAM20A) gene, and is characterized by amelogenesis imperfecta, delayed or failed tooth eruption, and periodontitis.
John Rong Hao Tay, Preethi Balan, Chaminda Jayampath Seneviratne   +2 more
wiley   +1 more source

BMP Signaling Pathway in Dentin Development and Diseases

Cells, 2022
BMP signaling plays an important role in dentin development. BMPs and antagonists regulate odontoblast differentiation and downstream gene expression via canonical Smad and non-canonical Smad signaling pathways.
Mengmeng Liu, Graham Goldman, Mary MacDougall, Shuo Chen   +3 more
doaj   +1 more source

The effect of fluoride on enamel and dentin formation in the uremic rat incisor [PDF]

, 2008
Renal impairment in children is associated with tooth defects that include enamel pitting and hypoplasia. However, the specific effects of uremia on tooth formation are not known.
A Al Nowaiser, AC Karim, Antonius L. J. J. Bronckers, CJ Spak, DM Lyaruu, Donacian M. Lyaruu, E Hossny, Fernando Santos, GP Wysocki, H Husdan, HH Schiffl, IB Salusky, JH Nunn, K Abe, K Nasstrom, M Torra, MB Leonard, MJ Koch, O Fejerskov, P Farge, Pamela DenBesten, PK Denbesten, PN Scutellari, Robert Mathias, RS Mathias, RS Mathias, T Murayama, VS Lucas, W Beertsen   +28 more
core   +1 more source

Y‐Box‐Binding Protein 1 Facilitates the Proliferation and Osteogenic Differentiation of Periodontal Ligament Stem Cells Through the Transcriptional Activation of FGF2‐Mediated Akt/GSK3β/β‐Catenin Signaling

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Periodontal ligament stem cells (PDLSCs) are derived from periodontal tissue and can differentiate into osteoblasts, which are ideal materials for alveolar bone repair and periodontal tissue regeneration. In this study, we aimed to explore the effects of Y‐box binding protein 1 (YB‐1) on the osteogenic differentiation and proliferation of ...
Yun‐Hao Xi, Chang‐Shun Li, Pin‐Lin Wu, Xiao‐Yang Zhou, Qian‐Wen Li, Cheng‐Hui Shen   +5 more
wiley   +1 more source

Cytotoxicity and biocompatibility of direct and indirect pulp capping materials [PDF]

, 2009
There are several studies about the cytotoxic effects of dental materials in contact with the pulp tissue, such as calcium hydroxide (CH), adhesive systems, resin composite and glass ionomer cements.
ATTA, Maria Teresa, CASAS-APAYCO, Leslie Caroll, COSTA, Carlos Alberto de Souza, HEBLING, Josimeri, MODENA, Karin Cristina da Silva, NAVARRO, Maria Fidela de Lima, SANTOS, Carlos Ferreira, SIPERT, Carla Renata   +7 more
core   +3 more sources