Results 1 to 10 of about 7,133 (255)

Piezo1 Regulates Odontogenesis via a FAM83G-Mediated Mechanism in Dental Papilla Cells In Vitro and In Vivo [PDF]

Biomolecules
This study explored the role of Piezo1 in the odontogenic differentiation of dental papilla cells (DPCs) and tissue, focusing on a mechanism involving family with sequence similarity 83, member G (FAM83G). Here, we found Piezo1, a mechanosensitive cation
Xinyue Sheng, Jingzhou Li, Haozhen Ma, Hongwen He, Qin Liu, Shilin Jia, Fuping Zhang, Fang Huang   +7 more
doaj   +4 more sources

Spatial and temporal gene expression patterns during early human odontogenesis process [PDF]

Frontiers in Bioengineering and Biotechnology
Studies on odontogenesis are of great importance to treat dental abnormalities and tooth loss. However, the odontogenesis process was poorly studied in humans, especially at the early developmental stages.
Yejia Yu, Kun Wang, Zhuo Wang, Haoyang Cai, Chengcheng Liao, Yutao Wu, Jingyi Zhang, Weidong Tian, Li Liao   +8 more
doaj   +3 more sources

Role of Cell Death in Cellular Processes During Odontogenesis

Frontiers in Cell and Developmental Biology, 2021
The development of a tooth germ in a precise size, shape, and position in the jaw, involves meticulous regulation of cell proliferation and cell death.
Poongodi Geetha-loganathan, Marie ŠUlcov, Marcela Buchtova   +2 more
exaly   +3 more sources

Tissue-Engineered Odontogenesis

Journal of Hard Tissue Biology, 2005
In this study, we have developed a tooth regeneration model derived from mouse tooth germ cells based on tissue engineering. Lower first molars from DDY mice embryos at E 14 were used. Biodegradable Polyglycolate acid (PGA) scaffolds were fabricated, seeded with dissociated the first molars cells, and implanted into the subcapsular layer of kidney in ...
Shinji Iwatsuki, Masaki Honda, Hidemitsu Harada, Minoru Ueda   +3 more
openalex   +4 more sources

MicroRNA-enriched small extracellular vesicles possess odonto-immunomodulatory properties for modulating the immune response of macrophages and promoting odontogenesis

Stem Cell Research and Therapy, 2020
Background To investigate the odonto-immunomodulatory properties of dental pulp stem cell-derived small extracellular vesicles (DPSCs-sEV), which promote odontogenesis by switching macrophages toward the pro-healing M2 phenotype.
Jianmao Zheng, Xiaoli Hu, Junqi Ling
exaly   +2 more sources

Pleiotrophin Expression during Odontogenesis [PDF]

Journal of Histochemistry & Cytochemistry, 2012
Pleiotrophin (PTN) is an extracellular matrix–associated growth factor and chemokine expressed in mesodermal and ectodermal cells. It plays an important role in osteoblast recruitment and differentiation. There is limited information currently available about PTN expression during odontoblast differentiation and tooth formation, and thus the authors ...
Heidi Erlandsen, Jennifer E. Ames, Amena Tamkenath, Olga Mamaeva, Katherine Stidham, Mary E. Wilson, Pablo Pérez‐Piñera, Thomas F. Deuel, Mary MacDougall   +8 more
openalex   +4 more sources

Role of Primary Cilia in Odontogenesis [PDF]

Journal of Dental Research, 2017
Primary cilium is a solitary organelle that emanates from the surface of most postmitotic mammalian cells and serves as a sensory organelle, transmitting the mechanical and chemical cues to the cell. Primary cilia are key coordinators of various signaling pathways during development and maintenance of tissue homeostasis.
Marek Hampl, Marek Hampl, Marcela Buchtová, Marcela Buchtová, Petra Celá, Petra Celá, Pavel Krejci, M. Kunova Bosakova, Hana Dosedelova, H.L. Szabo-Rogers   +9 more
exaly   +4 more sources

Cathepsin K‐Positive Cell Lineage Promotes In Situ Dentin Formation Controlled by Nociceptive Sonic Hedgehog [PDF]

Advanced Science
Oral diseases affect nearly half of the global population throughout their lifetime causing pain, as estimated by the World Health Organization. Preservation of vital pulp is the therapeutic core as well as a challenge to protect natural teeth.
Ruoshi Xu, Xiaohan Zhang, Weimin Lin, Yushun Wang, Danting Zhang, Shuang Jiang, Linfeng Liu, Jiaying Wang, Xutao Luo, Xiao Zhang, Junjun Jing, Quan Yuan, Chenchen Zhou   +12 more
doaj   +2 more sources

Small RNAs and tooth development: The role of microRNAs in tooth agenesis and impaction [PDF]

Journal of Dental Sciences
Background/purpose: Tooth development, or odontogenesis, is a complex process in which several molecular pathways play a key role. Recently, microRNAs, a class of approximately 20-nucleotide small RNA molecules that regulate gene expression, have been ...
Agnese Giovannetti, Rosanna Guarnieri, Francesco Petrizzelli, Sara Lazzari, Gabriella Padalino, Alice Traversa, Alessandro Napoli, Roberto Di Giorgio, Antonio Pizzuti, Chiara Parisi, Tommaso Mazza, Ersilia Barbato, Viviana Caputo   +12 more
doaj   +2 more sources

Molecular insight into odontogenesis in hyperglycemic environment: A systematic review

Journal of Pharmacy and Bioallied Sciences, 2020
Diabetes mellitus is an endocrinal disorder affecting worldwide and the disease incidence is rising alarmingly high. The effects of diabetes on tooth development are explored by limited studies and their molecular insights are very rarely studied.
Andamuthu Yamunadevi, Ramani Pratibha, Muthusamy Rajmohan, Nalliappan Ganapathy, Jeyachandran Porkodisudha, Dhanasing Pavithrah, Sengottaiyan Mahendraperumal   +6 more
doaj   +2 more sources