Results 1 to 10 of about 5,498 (234)

Cathepsin K-Positive Cell Lineage Promotes In Situ Dentin Formation Controlled by Nociceptive Sonic Hedgehog. [PDF]

Adv Sci (Weinh)
Mouse molar pulp Ctsk+ cells contribute to neonatal odontogenesis and reactionary dentin formation even if aging. Nociceptive nerve, more than conducting pain, secrets Shh to promote such process. Exogenous Shh reactivates Ctsk+ cells and expands the limit of pulp self‐repairing capability to enhance reparative dentin, even apex development, hopefully ...
Xu R, Zhang X, Lin W, Wang Y, Zhang D, Jiang S, Liu L, Wang J, Luo X, Zhang X, Jing J, Yuan Q, Zhou C.   +12 more
europepmc   +3 more sources

Craniofacial and Dental Anomalies of a Patient Carrying Two MicroRNA Variants: A Proof-Of-Concept Case Report. [PDF]

Clin Case Rep
ABSTRACT Craniofacial and dentofacial anomalies often result from disruptions in embryogenetic processes driven by genetic alterations. Dental development involves complex interactions between coding and non‐coding genes, orchestrated by a network of signaling pathways.
Grenga C, Guarnieri R, Mezio M, De Stefano AA, Galluccio G, Di Giorgio R, Giovannetti A, Pizzuti A, Caputo V, Barbato E.   +9 more
europepmc   +2 more sources

Role of Primary Cilia in Odontogenesis [PDF]

Journal of Dental Research, 2017
Primary cilium is a solitary organelle that emanates from the surface of most postmitotic mammalian cells and serves as a sensory organelle, transmitting the mechanical and chemical cues to the cell. Primary cilia are key coordinators of various signaling pathways during development and maintenance of tissue homeostasis.
Marek Hampl, Marek Hampl, Marcela Buchtová, Marcela Buchtová, Petra Celá, Petra Celá, Pavel Krejci, M. Kunova Bosakova, Hana Dosedelova, H.L. Szabo-Rogers   +9 more
exaly   +4 more sources

Ameloblastic Fibroma of the Mandible Presenting as a Dentinoid Formation in an 8-Year-Old Child: A Case Report. [PDF]

Clin Case Rep
ABSTRACT Ameloblastic fibroma is an uncommon, benign, mixed odontogenic tumor characterized by the presence of both epithelial and mesenchymal components, without the formation of hard tissue. It constitutes approximately 1.5%–4.5% of all odontogenic tumors and predominantly affects the posterior mandible.
Karna P, Rastogi V, Dhungel D, Chaurasia S.   +3 more
europepmc   +2 more sources

Integrating Phosphate Enhances Biomineralization Effect of Methacrylate Cement in Vital Pulp Treatment with Improved Human Dental Pulp Stem Cells Stimulation. [PDF]

Adv Healthc Mater
The integration of phosphate‐based glass into methylmethacrylate‐based cement (PIMC) presents promising characteristics for vital pulp treatment. PIMC demonstrates persistent strength and stability in wet conditions, effectively controls initial inflammation, and stimulates human dental pulp stem cells.
Ryu JH, Mangal U, Kwon JS, Seo JY, Byun SY, Lee YH, Jang S, Hwang G, Ku H, Shin Y, Kim D, Choi SH.   +11 more
europepmc   +2 more sources

Exploration of Dentition Development and Replacement in Two Forms of Mexican Tetra (Astyanax mexicanus). [PDF]

Anat Histol Embryol
ABSTRACT There are two main subforms of the teleost fish Mexican tetra (Astyanax mexicanus): the river‐dwelling surface fish and the cave‐dwelling blind cavefish. Recently, this species has become a popular animal model in developmental biology research. It was reported that cavefish bore more teeth than surface fish; however, a detailed description of
Fang Z, Atukorallaya D.
europepmc   +2 more sources

Non-Surgical Treatment of Bilateral Dens Invaginatus in Maxillary Lateral Incisors: A Case Report. [PDF]

Clin Case Rep
ABSTRACT Dens invaginatus (DI) is a dental developmental malformation, with 43% of the reported cases involving bilateral occurrence. Based on its manifestations, DI is classified into different types. Due to the complex anatomy, teeth with DI are more susceptible to caries and pulpitis and are commonly associated with incomplete root formation.
Chamani A, Forghani M, Asadi G.
europepmc   +2 more sources

Expression of FAM20C in the Osteogenesis and Odontogenesis of Mouse [PDF]

Journal of Histochemistry and Cytochemistry, 2010
Mutations in FAM20C were recently identified as the cause of lethal osteosclerotic bone dysplasia, which highlighted the important role of this molecule in biomineralization. No systematic studies have been performed to evaluate the expression pattern of this relatively new molecule in the developmental processes of bone and tooth.
X Wang, Chunlin Qin
exaly   +4 more sources

Electric field promoted odontogenic differentiation of stem cells from apical papilla by remodelling cytoskeleton. [PDF]

Int Endod J
Abstract Aim This study examined the impact of direct current electric fields (DCEFs) on the biological properties of stem cells derived from the apical papilla (SCAP) and further elucidated the underlying mechanisms involved in odontogenic differentiation induced by DCEFs stimulation.
Li X, Zhao S, Liu Y, Gu Y, Qiu L, Chen X, Sloan AJ, Song B.   +7 more
europepmc   +2 more sources

Expression and Function of NUMB in Odontogenesis [PDF]

BioMed Research International, 2013
NUMB is a multifunctional protein implicated to function in self-renewal and differentiation of progenitors in several tissues. To characterize the transcripts and to analyze the expression pattern of NUMB in odontogenesis, we isolated 2 full-length clones for NUMB from mouse dental pulp mRNA.
Anne George, Carlotta A. Evans, Yiqiang Song, Qi Gao, Amsaveni Ramachandran, Sriram Ravindran, Haitao Li   +6 more
openaire   +2 more sources