Molecular insight into odontogenesis in hyperglycemic environment: A systematic review
Journal of Pharmacy and Bioallied Sciences, 2020 Diabetes mellitus is an endocrinal disorder affecting worldwide and the disease incidence is rising alarmingly high. The effects of diabetes on tooth development are explored by limited studies and their molecular insights are very rarely studied.
Andamuthu Yamunadevi +6 more
doaj +2 more sources
The tick tock of odontogenesis [PDF]
Experimental Cell Research, 2014 Although a big deal of dental research is being focused to the understanding of early stages of tooth development, a huge gap exist on our knowledge on how the dental hard tissues are formed and how this process is controlled daily in order to produce very complex and diverse tooth shapes adapted for specific functions.
Li, Zheng +6 more
openaire +4 more sources
Sonic Hedgehog Signaling and Development of the Dentition [PDF]
Journal of Developmental Biology, 2017 Sonic hedgehog (Shh) is an essential signaling peptide required for normal embryonic development. It represents a highly-conserved marker of odontogenesis amongst the toothed vertebrates.
Maisa Seppala +4 more
doaj +3 more sources
Piezo1 Regulates Odontogenesis via a FAM83G-Mediated Mechanism in Dental Papilla Cells In Vitro and In Vivo [PDF]
BiomoleculesThis study explored the role of Piezo1 in the odontogenic differentiation of dental papilla cells (DPCs) and tissue, focusing on a mechanism involving family with sequence similarity 83, member G (FAM83G). Here, we found Piezo1, a mechanosensitive cation
Xinyue Sheng +7 more
doaj +2 more sources
Spatial and temporal gene expression patterns during early human odontogenesis process [PDF]
Frontiers in Bioengineering and BiotechnologyStudies on odontogenesis are of great importance to treat dental abnormalities and tooth loss. However, the odontogenesis process was poorly studied in humans, especially at the early developmental stages.
Yejia Yu +8 more
doaj +2 more sources
The metamorphic transition of the frog mouth: from tadpole keratinized mouthparts to adult teeth [PDF]
Royal Society Open ScienceTeeth have been a prominent feature of most vertebrates for 400 million years, and the core regulatory network underlying embryonic tooth formation is deeply conserved.
Daniel J. Paluh +6 more
doaj +2 more sources
Cathepsin K‐Positive Cell Lineage Promotes In Situ Dentin Formation Controlled by Nociceptive Sonic Hedgehog [PDF]
Advanced ScienceOral diseases affect nearly half of the global population throughout their lifetime causing pain, as estimated by the World Health Organization. Preservation of vital pulp is the therapeutic core as well as a challenge to protect natural teeth.
Ruoshi Xu +12 more
doaj +2 more sources
Impact of FasL Stimulation on Sclerostin Expression and Osteogenic Profile in IDG-SW3 Osteocytes
Biology, 2021 The Fas ligand (FasL) is known from programmed cell death, the immune system, and recently also from bone homeostasis. As such, Fas signalling is a potential target of anti-osteoporotic treatment based on the induction of osteoclastic cell death.
Adela Kratochvilova +6 more
doaj +1 more source
Ectopic premolar tooth in the sigmoid notch [PDF]
, 2016 Impaction of a mandibular premolar is relatively uncommon. Ectopic placement is more unusual and there has been no discussion in the literature of an ectopic mandibular premolar in the coronoid process. In this case report, we present an impacted ectopic
Akgul, Hayati Murat +2 more
core +13 more sources
Immunomodulation stimulates the innervation of engineered tooth organ [PDF]
, 2014 The sensory innervation of the dental mesenchyme is essential for tooth function and protection. Sensory innervation of the dental pulp is mediated by axons originating from the trigeminal ganglia and is strictly regulated in time. Teeth can develop from
Bécavin, Thibault +5 more
core +17 more sources