Spatial and temporal gene expression patterns during early human odontogenesis process [PDF]
Frontiers in Bioengineering and BiotechnologyStudies on odontogenesis are of great importance to treat dental abnormalities and tooth loss. However, the odontogenesis process was poorly studied in humans, especially at the early developmental stages.
Yejia Yu +8 more
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Piezo1 Regulates Odontogenesis via a FAM83G-Mediated Mechanism in Dental Papilla Cells In Vitro and In Vivo [PDF]
BiomoleculesThis study explored the role of Piezo1 in the odontogenic differentiation of dental papilla cells (DPCs) and tissue, focusing on a mechanism involving family with sequence similarity 83, member G (FAM83G). Here, we found Piezo1, a mechanosensitive cation
Xinyue Sheng +7 more
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Spatiotemporal Expression Patterns of Critical Genes Involved in FGF Signaling During Morphogenesis and Odontogenesis of Deciduous Molars in Miniature Pigs [PDF]
International Journal of Medical Sciences, 2021 The fibroblast growth factor (FGF) pathway plays an important role in epithelial-mesenchymal interactions during tooth development. Nevertheless, how the ligands, receptors, and antagonists of the FGF pathway are involved in epithelial-mesenchymal ...
Wenwen Guo +9 more
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Single nucleotide polymorphisms in odontogenesis-related genes associated with tooth-size discrepancy [PDF]
Australasian Orthodontic Journal, 2023 Introduction: The present study aimed to determine the association between single nucleotide polymorphisms (SNPs) in RUNX2, SMAD6, BMP2, and BMP4 genes in relation to tooth-size discrepancy (TSD).
Caio Luiz Bitencourt Reis +7 more
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Role of Cell Death in Cellular Processes During Odontogenesis
Frontiers in Cell and Developmental Biology, 2021 The development of a tooth germ in a precise size, shape, and position in the jaw, involves meticulous regulation of cell proliferation and cell death.
John Abramyan +5 more
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Multifunctional Exosomes Derived from M2 Macrophages with Enhanced Odontogenesis, Neurogenesis and Angiogenesis for Regenerative Endodontic Therapy: An In Vitro and In Vivo Investigation [PDF]
BiomedicinesIntroduction: Exosomes derived from M2 macrophages (M2-Exos) exhibit tremendous potential for inducing tissue repair and regeneration. Herein, this study was designed to elucidate the biological roles of M2-Exos in regenerative endodontic therapy (RET ...
Yujie Wang +4 more
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Stem Cell Research & Therapy, 2020 Background To investigate the odonto-immunomodulatory properties of dental pulp stem cell-derived small extracellular vesicles (DPSCs-sEV), which promote odontogenesis by switching macrophages toward the pro-healing M2 phenotype.
Jianmao Zheng +7 more
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The role of autophagy in odontogenesis, dental implant surgery, periapical and periodontal diseases [PDF]
Journal of Cellular and Molecular MedicineAutophagy is a cellular process that is evolutionarily conserved, involving the sequestration of damaged organelles and proteins into autophagic vesicles, which subsequently fuse with lysosomes for degradation.
Sevinç İnan, Emre BARIŞ
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Tissue-Engineered Odontogenesis
Journal of Hard Tissue Biology, 2005 In this study, we have developed a tooth regeneration model derived from mouse tooth germ cells based on tissue engineering. Lower first molars from DDY mice embryos at E 14 were used. Biodegradable Polyglycolate acid (PGA) scaffolds were fabricated, seeded with dissociated the first molars cells, and implanted into the subcapsular layer of kidney in ...
Shinji Iwatsuki +3 more
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Pleiotrophin Expression during Odontogenesis [PDF]
Journal of Histochemistry & Cytochemistry, 2012 Pleiotrophin (PTN) is an extracellular matrix–associated growth factor and chemokine expressed in mesodermal and ectodermal cells. It plays an important role in osteoblast recruitment and differentiation. There is limited information currently available about PTN expression during odontoblast differentiation and tooth formation, and thus the authors ...
Heidi Erlandsen +8 more
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