Spatial and temporal gene expression patterns during early human odontogenesis process. [PDF]
Studies on odontogenesis are of great importance to treat dental abnormalities and tooth loss. However, the odontogenesis process was poorly studied in humans, especially at the early developmental stages.
Yu Y+8 more
europepmc +4 more sources
Molecular insight into odontogenesis in hyperglycemic environment: A systematic review
Diabetes mellitus is an endocrinal disorder affecting worldwide and the disease incidence is rising alarmingly high. The effects of diabetes on tooth development are explored by limited studies and their molecular insights are very rarely studied.
Andamuthu Yamunadevi+6 more
doaj +3 more sources
Piezo1 Regulates Odontogenesis via a FAM83G-Mediated Mechanism in Dental Papilla Cells In Vitro and In Vivo. [PDF]
This study explored the role of Piezo1 in the odontogenic differentiation of dental papilla cells (DPCs) and tissue, focusing on a mechanism involving family with sequence similarity 83, member G (FAM83G). Here, we found Piezo1, a mechanosensitive cation
Sheng X+7 more
europepmc +4 more sources
Spatiotemporal Expression Patterns of Critical Genes Involved in FGF Signaling During Morphogenesis and Odontogenesis of Deciduous Molars in Miniature Pigs [PDF]
The fibroblast growth factor (FGF) pathway plays an important role in epithelial-mesenchymal interactions during tooth development. Nevertheless, how the ligands, receptors, and antagonists of the FGF pathway are involved in epithelial-mesenchymal ...
Wenwen Guo+9 more
semanticscholar +2 more sources
Single nucleotide polymorphisms in odontogenesis-related genes associated with tooth-size discrepancy [PDF]
Introduction: The present study aimed to determine the association between single nucleotide polymorphisms (SNPs) in RUNX2, SMAD6, BMP2, and BMP4 genes in relation to tooth-size discrepancy (TSD).
Caio Luiz Bitencourt Reis+7 more
semanticscholar +2 more sources
Polydopamine-coated bioactive glass for immunomodulation and odontogenesis in pulpitis. [PDF]
Li J+6 more
europepmc +3 more sources
The role of autophagy in odontogenesis, dental implant surgery, periapical and periodontal diseases [PDF]
Autophagy is a cellular process that is evolutionarily conserved, involving the sequestration of damaged organelles and proteins into autophagic vesicles, which subsequently fuse with lysosomes for degradation.
Sevinç Inan, Emre Barış
semanticscholar +2 more sources
Multifunctional Exosomes Derived from M2 Macrophages with Enhanced Odontogenesis, Neurogenesis and Angiogenesis for Regenerative Endodontic Therapy: An In Vitro and In Vivo Investigation [PDF]
Introduction: Exosomes derived from M2 macrophages (M2-Exos) exhibit tremendous potential for inducing tissue repair and regeneration. Herein, this study was designed to elucidate the biological roles of M2-Exos in regenerative endodontic therapy (RET ...
Yujie Wang+4 more
semanticscholar +2 more sources
Tissue-Engineered Odontogenesis
In this study, we have developed a tooth regeneration model derived from mouse tooth germ cells based on tissue engineering. Lower first molars from DDY mice embryos at E 14 were used. Biodegradable Polyglycolate acid (PGA) scaffolds were fabricated, seeded with dissociated the first molars cells, and implanted into the subcapsular layer of kidney in ...
Masaki J. Honda+5 more
openaire +4 more sources
Pleiotrophin Expression during Odontogenesis [PDF]
Pleiotrophin (PTN) is an extracellular matrix–associated growth factor and chemokine expressed in mesodermal and ectodermal cells. It plays an important role in osteoblast recruitment and differentiation. There is limited information currently available about PTN expression during odontoblast differentiation and tooth formation, and thus the authors ...
Amena Tamkenath+8 more
openaire +4 more sources