Results 31 to 40 of about 7,133 (255)

Notum as a Crucial Regulator of Matrix Integrity in Dentinogenesis. [PDF]

J Cell Physiol
With Notum deficiency, mouse dentin exhibits a thicker yet dysplastic structure with disrupted tubular organization, resulting in functionally compromised dentin. Notum precisely regulates Wnt/β‐catenin signaling within the dentin‐pulp complex to support dentin formation.
Choi H, Jeong JK, Adasooriya D, Cho SW, Cho ES.   +4 more
europepmc   +2 more sources

Downregulation of FGF Signaling by Spry4 Overexpression Leads to Shape Impairment, Enamel Irregularities, and Delayed Signaling Center Formation in the Mouse Molar. [PDF]

, 2019
FGF signaling plays a critical role in tooth development, and mutations in modulators of this pathway produce a number of striking phenotypes. However, many aspects of the role of the FGF pathway in regulating the morphological features and the mineral ...
Ahn, Youngwook, Charles, Cyril, Ganss, Bernhard, Jheon, Andrew, Klein, Ophir D, Krumlauf, Robb, Marangoni, Pauline, Seidel, Kerstin, Viriot, Laurent   +8 more
core   +1 more source

In vitro evaluation of periapical lesion‐derived stem cells for dental pulp tissue engineering

FEBS Open Bio, 2022
Dental pulp tissue engineering is a promising alternative treatment for pulpitis and periapical periodontitis, and dental pulp stem cells (DPSCs) are considered to be the gold standard for dental seed cell research.
Weiping Li, Mengying Mao, Nan Hu, Jia Wang, Jing Huang, Shensheng Gu   +5 more
doaj   +1 more source

Accuracy of Demirjian’s, Willems, Nolla’s and Modified Cameriere’s Dental Age Estimation Methods in Young Western Indian Children- A Cross-sectional Study [PDF]

Journal of Clinical and Diagnostic Research, 2022
Introduction: In forensic odontology, Dental Age (DA) assessment has gained popularity, since it is less variable than other indices and is less impacted by environmental variables.
Anshula Deshpande, Neha Pradhan, Kinjal Patel   +2 more
doaj   +1 more source

Wnt signaling during tooth replacement in zebrafish (Danio rerio) : pitfalls and perspectives [PDF]

, 2014
The canonical (13-catenin dependent) Wnt signaling pathway has emerged as a likely candidate for regulating tooth replacement in continuously renewing dentitions.
Elderweirdt, Fien, Huysseune, Ann, Soenens, Mieke   +2 more
core   +3 more sources

Nonsyndromic gemination-associated microdontia: A report of an unusual case

Indian Journal of Dental Sciences, 2023
Tooth gemination is a dental anomaly that results from an incomplete attempt of a single tooth germ to separate during morphodifferentiation stage of odontogenesis, and it usually exhibits a large bifid crown with a single common root and root canal ...
Laboni Ghorai, Mayukh Bhattacharya
doaj   +1 more source

Test Tube Tooth: The Next Big Thing [PDF]

Journal of Clinical and Diagnostic Research, 2016
Unlike some vertebrates and fishes, humans do not have the capacity for tooth regeneration after the loss of permanent teeth. Although artificial replacement with removable dentures, fixed prosthesis and implants is possible through advances in the ...
Preeti Yadav, Mohammed Tahir, Harsh Yadav, Rakshit Sureka, Aarti Garg   +4 more
doaj   +1 more source

Increasing Odontoblast-like Differentiation from Dental Pulp Stem Cells through Increase of β-Catenin/p-GSK-3β Expression by Low-Frequency Electromagnetic Field

Biomedicines, 2021
Odontoblasts produce proteins that form the dentinal extracellular matrix, which can protect the dental pulp from external stimuli and is required for tooth regeneration.
Han-Moi Lim, Myeong-Hyun Nam, Yu-Mi Kim, Young-Kwon Seo   +3 more
doaj   +1 more source

Etiology Study of Acquired Developmental Defects of Enamel and Their Association with Dental Caries in Children between 3 and 19 Years Old from Dolj County, Romania

Children, 2022
Background: Developmental defects of enamel (DDE) are frequently encountered in primary and permanent teeth, yet their etiology is not completely known. Enamel hypoplasia is considered a predisposing factor for early caries.
Mihai Popescu, Mihaela Ionescu, Monica Scrieciu, Sanda Mihaela Popescu, Răzvan Mercuţ, Marina Olimpia Amărăscu, Monica Mihaela Iacov Crăiţoiu, Daniela Lazăr, Veronica Mercuţ   +8 more
doaj   +1 more source

Rare and Common Variants Conferring Risk of Tooth Agenesis [PDF]

, 2018
We present association results from a large genome-wide association study of tooth agenesis (TA) as well as selective TA, including 1,944 subjects with congenitally missing teeth, excluding third molars, and 338,554 controls, all of European ancestry. We
Alonso, I. (I.), Audolfsson, G. (G.), Bjornsdottir, G. (G.), Dhamo, B. (Brunilda), Feenstra, B. (Bjarke), Geller, F. (Frank), Gudbjartsson, D.F. (Daniel), Gudmundsson, L. (Larus), Gustafsson, O. (Omar), Howe, B.J. (B. J.), Ingason, A. (A.), Jonsson, L. (L.), Jonsson, R. (R.), Jonsson, T. (Thorvaldur), Leslie, E.J. (Elizabeth J.), Magnusson, T.E. (T. E.), Marazita, M.L. (Mary), Melbye, M. (Mads), Moreno Uribe, L.M. (L. M.), Nawaz, M.S. (M. S.), Nohr, C. (Christian), Oddsson, A. (A.), Olafsson, S. (S.), Ongkosuwito, E.M. (Edwin), Pinho, T. (T.), Rivadeneira, F. (F.), Santos, M. (M.), Stefansson, H. (Hreinn), Stefansson, K. (K.), Steinberg, S. (Stacy), Thordarson, A. (A.), Unnsteinsdottir, U. (U.), Vučić, S. (Strahinja), Walters, G.B. (Bragi), Wolvius, E.B. (Eppo), Zervas, M. (M.)   +35 more
core   +2 more sources