Results 41 to 50 of about 10,398 (278)
Loss of Bmp2 impairs odontogenesis via dysregulating pAkt/pErk/GCN5/Dlx3/Sp7
Research Square, 2023 BMP2 signaling plays a pivotal role in odontoblast differentiation and maturation during odontogenesis. Teeth lacking Bmp2 exhibit a morphology reminiscent of dentinogenesis imperfecta (DGI), associated with mutations in dentin matrix protein 1 (DMP1 ...
Shuo Chen +9 more
semanticscholar +1 more source
Expression and Function of NUMB in Odontogenesis [PDF]
BioMed Research International, 2013 NUMB is a multifunctional protein implicated to function in self-renewal and differentiation of progenitors in several tissues. To characterize the transcripts and to analyze the expression pattern of NUMB in odontogenesis, we isolated 2 full-length clones for NUMB from mouse dental pulp mRNA.
Anne George +6 more
openaire +2 more sources
Stem cell research & therapeutics, 2021 SATB2-associated syndrome (SAS) is a multisystem disorder caused by mutation of human SATB2 gene. Tooth agenesis is one of the most common phenotypes observed in SAS.
T. Xin +7 more
semanticscholar +1 more source
Formation and Developmental Specification of the Odontogenic and Osteogenic Mesenchymes
Frontiers in Cell and Developmental Biology, 2020 Within the mandible, the odontogenic and osteogenic mesenchymes develop in a close proximity and form at about the same time. They both originate from the cranial neural crest. These two condensing ecto-mesenchymes are soon separated from each other by a
Eva Svandova +4 more
doaj +1 more source
Heterochronic truncation of odontogenesis in theropod dinosaurs provides insight into the macroevolution of avian beaks [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2017 Shuo Wang +7 more
openalex +2 more sources
The tick tock of odontogenesis [PDF]
Experimental Cell Research, 2014 Although a big deal of dental research is being focused to the understanding of early stages of tooth development, a huge gap exist on our knowledge on how the dental hard tissues are formed and how this process is controlled daily in order to produce very complex and diverse tooth shapes adapted for specific functions.
Doohak Kim +6 more
openaire +3 more sources
Coupling of angiogenesis and odontogenesis orchestrates tooth mineralization in mice
Journal of Experimental Medicine, 2022 Matsubara et al. identify an endothelial subtype that orchestrates hardening of teeth, the hardest tissue of the body. The reciprocal feedback between these capillaries and odontoblasts highlights both the similarities and differences between bones and ...
T. Matsubara +13 more
semanticscholar +1 more source
International Journal of Dentistry, 2022 Aim This in vitro study aimed to investigate the roles of aspirin (ASA) and its concentrations on the odontogenesis of human dental pulp cells (HDPCs) and to investigate the influence of ASA on TGF-β1 liberation from dentin. Methodology.
V. Khampatee, C. Zhang, L. Chou
semanticscholar +1 more source
Frontiers in Cell and Developmental Biology, 2023 As the dentition forms and becomes functional, the alveolar bone is remodelled. Metalloproteinases are known to contribute to this process, but new regulators are emerging and their contextualization is challenging.
S. Varadinkova +11 more
doaj +1 more source
Cell Death and Differentiation, 2022 Proteins expressed by the paired box gene 9 (PAX9) and Msh Homeobox 1 (MSX1) are intimately involved in tooth development (odontogenesis). The regulation of PAX9 and MSX1 protein turnover by deubiquitinating enzymes (DUBs) plausibly maintain the required
K. Kaushal +7 more
semanticscholar +1 more source