Results 61 to 70 of about 247,095 (344)

The Odyssey Approach for Optimizing Federated SPARQL Queries

open access: yes, 2017
Answering queries over a federation of SPARQL endpoints requires combining data from more than one data source. Optimizing queries in such scenarios is particularly challenging not only because of (i) the large variety of possible query execution plans ...
A Schwarte   +7 more
core   +1 more source

NPLDA: A Deep Neural PLDA Model for Speaker Verification

open access: yes, 2020
The state-of-art approach for speaker verification consists of a neural network based embedding extractor along with a backend generative model such as the Probabilistic Linear Discriminant Analysis (PLDA).
Ganapathy, Sriram   +2 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Tracking the Odyssey’s Plot through Dawn\u27s Epithets [PDF]

open access: yes, 2013
The three formulaic sunrises in Homer’s Odyssey share several characteristics. Particularly significant is the use of metrically similar epithets: rhododaktulos and xrusothronos, often translated “rose-fingered” and “golden-throned.” Previous scholarly ...
Hartwick, Kerry
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

‘D’oh Brother Where Art Thou’: Homer’s Women in The Simpsons and Contemporary Screen Adaptations

open access: yesHumanities, 2023
In the Odyssey, Homer’s Penelope and Circe have fundamentally important roles in ensuring the progression and success of the hero’s, Odysseus, journey home. Their actions in the Odyssey invite complex readings of the two women.
Alice Payne
doaj   +1 more source

The 115 GeV Higgs Odyssey [PDF]

open access: yes, 2000
On his way home from Troy, Odysseus had arrived within reach of Ithaca when a great storm blew up. He was swept away, and only several years later was he able to return to reclaim his rights from the rapacious suitors, with the aid of his son Telemachus.
Ellis, John
core   +1 more source

Odyssey of Auxin [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2010
The history of plant biology is inexorably intertwined with the conception and discovery of auxin, followed by the many decades of research to comprehend its action during growth and development. Growth responses to auxin are complex and require the coordination of auxin production, transport, and perception. In this overview of past auxin research, we
Steffen, Abel, Athanasios, Theologis
openaire   +2 more sources

Patients With High Genome-Wide Polygenic Risk Scores for Coronary Artery Disease May Receive Greater Clinical Benefit From Alirocumab Treatment in the ODYSSEY OUTCOMES Trial

open access: yesCirculation, 2019
Supplemental Digital Content is available in the text. Background: Alirocumab, an antibody that blocks PCSK9 (proprotein convertase subtilisin/kexin type 9), was associated with reduced major adverse cardiovascular events (MACE) and death in the ODYSSEY ...
A. Damask   +19 more
semanticscholar   +1 more source

The Influence of Social Determinants of Health on the Genetic Diagnostic Odyssey: Who Remains Undiagnosed, Why, and to What Effect?

open access: yesPediatric Research, 2020
Although Mendelian genetic disorders are individually rare, they are collectively more common and contribute disproportionately to pediatric morbidity and mortality. Remarkable advances in the past decade have led to identification of the precise genetic
Y. Fraiman, M. Wojcik
semanticscholar   +1 more source

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