Results 111 to 120 of about 18,586 (163)

Reproductive toxicity: in vivo testing guidelines from OECD

2022
The guidelines for testing the reproductive toxicity in vivo developed and validated by Organisation for Economic Cooperation and Development allow for a systematic and internationally accepted testing and assessment of chemicals. Within reproductive toxicity two main categories of guidelines are usually identified: one dedicated to testing ...
Estevan Martinez, Carmen, Pamies, David, SOGORB, MIGUEL A, Vilanova, Eugenio   +3 more
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ESTP comments on the draft updated OECD test guideline 407

Experimental and Toxicologic Pathology, 2008
The revision of the OECD TG 407 test guideline (repeated dose 28-day oral toxicity study in rodents) focuses on endpoints to detect endocrine activities of chemicals. The new endpoints are likely to influence other previously established core endpoints of this study type.
Elke, Hartmann, Volker, Strauss, Rolf, Eiben, Alexius, Freyberger, Wolfgang, Kaufmann, Ingo, Loof, Elke, Reissmueller, Matthias, Rinke, Christine, Ruehl-Fehlert, Frederic, Schorsch, Ludwig, Schladt   +10 more
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Replacing animal-derived components in in vitro test guidelines OECD 455 and 487

Science of The Total Environment, 2023
The evaluation of single substances or environmental samples for their genotoxic or estrogenic potential is highly relevant for human- and environment-related risk assessment. To examine the effects on a mechanism-specific level, standardized cell-based in vitro methods are widely applied.
Reichstein, Inska S., König, Maria, Wojtysiak, Niklas, Escher, Beate I., Henneberger, Luise, Behnisch, Peter, Besselink, Harrie, Thalmann, Beat, Colas, Julien, Hörchner, Sarah, Hollert, Henner, Schiwy, Andreas   +11 more
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The OECD Guidelines for the Testing of Chemicals and Pesticides

2012
In many countries the process of toxicity testing of environmental chemicals is ruled by a framework of OECD guidelines. The present paper will give an overview over the relevant OECD guidelines and guidance documents and mainly focus on methodological issues related to the prenatal toxicity testing guideline.
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Rationale of genotoxicity testing of nanomaterials: Regulatory requirements and appropriateness of available OECD test guidelines

Nanotoxicology, 2010
The development of an environmental health and safety risk management system for nanoscale particle-types requires a base set of hazard data. Accurate determination of health and environmental risks of nanomaterials is a function of the integration of hazard and exposure datasets.
David B, Warheit, E Maria, Donner
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Comparison of biodegradation performance of OECD test guideline 301C with that of other ready biodegradability tests

Environmental Toxicology and Chemistry, 2013
Abstract   The Organisation for Economic Co-operatoin and development (OECD) Guidelines for the Testing of Chemicals list 7 types of tests for determining the ready biodegradability of chemical compounds (301A–F and 310). The present study compares the biodegradation performance of test guideline 301C,
Takakazu, Kayashima, Masanori, Taruki, Kazuomi, Katagiri, Ryosuke, Nabeoka, Tomohiko, Yoshida, Toshiaki, Tsuji   +5 more
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OECD guidelines for testing of chemicals

2012
Other methods and guidelines not included in this publication may be judged to be appropriate in testing chemicals in certain scientifi c, legal, and administrative contexts.The OECD Council Decision on Mutual Acceptance of Data (12th May 1981; C[81]30) affi rms that data generated in one country in accordance with the OECD Test Guidelines – and ...
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OECD Activity on Endocrine Disrupters Test Guidelines Development

Ecotoxicology, 2000
The OECD endocrine disrupter activity was initiated in November 1996. A Task Force on Endocrine Disrupter Testing and Assessment (EDTA) has been established in 1997 to oversee the programme. One of the most important outcomes of EDTA is the development of an initial framework for the testing of endocrine disrupting substances consisting of three tiers,
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Effect of test concentration in the ready biodegradability test for chemical substances: Improvement of OECD test guideline 301C

Environmental Toxicology and Chemistry, 2015
Abstract   In Japan, understanding the environmental persistence of chemicals is very important for risk assessment, and ready biodegradability tests are mainly conducted according to the Organisation for Economic Co-operation and Development test guideline 301C.
Ryosuke, Nabeoka, Masanori, Taruki, Takakazu, Kayashima, Tomohiko, Yoshida, Takashi, Kameya   +4 more
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