Results 131 to 140 of about 565 (150)

Regulatory Effect and Mechanism of Oenothein B in Reducing Fat Accumulation in Caenorhabditis Elegans

European Journal of Lipid Science and Technology, 2023
AbstractOenothein B (OEB) displays various biological activities, including immunomodulatory, antioxidant, and anticancer effects. However, the underlying mechanisms remain unclear. Therefore, in this study, the effect of OEB isolated from Eucalyptus leaves on fat deposition and its underlying mechanism are explored in Caenorhabditis elegans （C.elegans)
Xiaoying Zhang, Qiaoxing Liu, Yun Chen, Wei Li, Konglong Feng, Jie Xiao, Yong Cao, Zuanxian Su, Guang Wang, Yunjiao Chen   +9 more
openaire   +1 more source

[Oenothein B inhibits proliferation and migration of breast cancer cells by regulating P53].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2023
The effects of oenothein B(OEB) on the proliferation, apoptosis, invasion, and migration of breast cancer MCF-7 and MDA-MB-231 cells were investigated by cell culture in vitro, network pharmacology, and molecular docking. In vitro cell experiments revealed that OEB inhibited the proliferation and colony formation ability, and promoted the apoptosis and
Mao-Hong, Luo, Ya, He, Hong, Li, Teng-Xiang, Chen, Shan, Lei, Jin-Juan, Zhang, Lu, Wang   +6 more
openaire   +1 more source

Determination of Macrocyclic Ellagitannin Oenothein B in Plant Materials by HPLC‐DAD‐MS: Method Development and Validation

Phytochemical Analysis, 2012
ABSTRACTIntroductionOenothein B (OeB) is a dimeric macrocyclic ellagitannin occurring mainly in the genus Oenothera. In the literature no validated HPLC method for quantification of this compound has been reported.ObjectiveTo develop and validate an efficient HPLC method for quantification of OeB in plant materials.MethodologyExtraction conditions of ...
Sebastian, Granica, Agnieszka, Bazylko, Anna K, Kiss   +2 more
openaire   +2 more sources

Age influences the lymphocyte response to the ellagitannin oenothein B and acai polysaccharides. (VET2P.1040)

The Journal of Immunology, 2014
Abstract The effects of nutritional supplements on immunity are still not well understood. For example, although aging affects immune cell responsiveness, it is not well known if immune stimulation by some nutritional supplements is also affected by aging.
Andrew Ramstead, Igor Schepetkin, Mark Quinn, Mark Jutila   +3 more
openaire   +1 more source

Oenothein B boosts antioxidant capacity and supports metabolic pathways that regulate antioxidant defense inCaenorhabditis elegans

Food & Function, 2020
This study provides new insights into the effects of OEB treatment on antioxidant capacity and metabolism that suggest that OEB could be used as a good source of natural antioxidants.
Wei Li, Ziyin Li, Ming-Jun Peng, Xiaoying Zhang, Yunjiao Chen, Yu-Yu Yang, Xiao-Xiang Zhai, Guo Liu, Yong Cao   +8 more
openaire   +2 more sources

Oenothein B inhibits the expression ofPbFKS1transcript and induces morphological changes inParacoccidioides brasiliensis

Medical Mycology, 2007
The fungus Paracoccidioides brasiliensis is the causative agent of paracoccidioidomycosis (PCM), the most prevalent human systemic mycosis in Latin America. Drug toxicity and the appearance of resistant strains have created the need to search for new therapeutic approaches.
Glaciane D, Santos, Pedro H, Ferri, Suzana C, Santos, Sônia N, Bao, Célia M A, Soares, Maristela, Pereira   +5 more
openaire   +2 more sources

Investigation on the Interaction Behavior Between Oenothein B and Pepsin by Isothermal Titration Calorimetry and Spectral Studies

Journal of Food Science, 2019
Abstract Oenothein B (OeB) is a dimeric macrocyclic ellagitannin isolated from Herbs and fruits that have a variety of biological activities. In order to better understand the effect of OeB on the activity of the digestive enzyme pepsin, interactions between OeB and pepsin were investigated in vitro under ...
Zitao Liu, Li Wang, Lei Shi, Xun Chen, Yanlei Chang, Yong Cao, Lichao Zhao   +6 more
openaire   +2 more sources

Oenothein B, a dimeric, hydrolysable tannin with macrocyclic structure, and accompanying tannins from Oenothera erythrosepala

Journal of the Chemical Society, Perkin Transactions 1, 1990
A new dimeric, hydrolysable tannin which we have named oenothein B (1), and eight accompanying compounds, including oenothein C (2), were isolated from the leaves of Oenothera erythrosepala. The macrocyclic structure of compound (1) was established from chemical and spectroscopic data.
Tsutomu Hatano, Taeko Yasuhara, Muneto Matsuda, Kazufumi Yazaki, Takashi Yoshida, Takuo Okuda   +5 more
openaire   +1 more source

Investigation on the inactivation of trypsin by oenothein B: isothermal titration calorimetry and docking studies

International Journal of Food Science & Technology, 2019
SummaryThe aim of this study was to investigate the inhibitory mechanism of oenothein B (OeB), a unique oligomer ellagitannin with a rigid structure, on porcine trypsin using fluorescence spectroscopy, isothermal titration calorimetry (ITC), circular dichroism (CD) and molecular docking.
Li Wang, Huijun Liang, Zitao Liu, Jingfeng Zhang, Yu Wang, Jian Xiao, Lichao Zhao   +6 more
openaire   +1 more source

Genotoxicity and cytotoxicity evaluation of oenothein B and its protective effect against mitomycin C-induced mutagenic action

Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2014
The natural product oenothein B (OeB), a dimeric macrocyclic ellagitannin, has a wide range of biological activities, such as antioxidant, anti-inflammatory, anti-viral, antifungal, and antitumor. However, investigations concerning its genotoxicity have not been carried out.
Cinthia Aparecida, Silva, Carolina Ribeiro, Silva, Jefferson Hollanda, Véras, Lee, Chen-Chen, Pedro Henrique, Ferri, Suzana da Costa, Santos   +5 more
openaire   +2 more sources