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Effect of <i>Epilobium angustifolium</i> Extract Containing Oenothein B on Autophagy

YAKUGAKU ZASSHI
Yuki Mukai, Ryota Yoshimura, Yuriko Naka, Junichi Tsuruoka, Koichiro Ohnuki   +4 more
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Oenothein B's contribution to the anti-inflammatory and antioxidant activity of Epilobium sp

Phytomedicine, 2011
Willow herb tea or preparation are available and relatively popular in the European market, and claimed to be effective inter alia because of their anti-inflammatory activity. The present study is therefore aimed at comparing the anti-inflammatory and antioxidant activity of extracts of the three most popular Epilobium species (E.
Anna K Kiss, Agnieszka Bazylko, Agnieszka Filipek   +2 more
exaly   +3 more sources

Investigation on the Interaction Behavior Between Oenothein B and Pepsin by Isothermal Titration Calorimetry and Spectral Studies

Journal of Food Science, 2019
Abstract Oenothein B (OeB) is a dimeric macrocyclic ellagitannin isolated from Herbs and fruits that have a variety of biological activities. In order to better understand the effect of OeB on the activity of the digestive enzyme pepsin, interactions between OeB and pepsin were investigated in vitro under ...
Zitao Liu, Li Wang, Xun Chen
exaly   +3 more sources

Determination of Macrocyclic Ellagitannin Oenothein B in Plant Materials by HPLC‐DAD‐MS: Method Development and Validation

Phytochemical Analysis, 2012
ABSTRACTIntroductionOenothein B (OeB) is a dimeric macrocyclic ellagitannin occurring mainly in the genus Oenothera. In the literature no validated HPLC method for quantification of this compound has been reported.ObjectiveTo develop and validate an efficient HPLC method for quantification of OeB in plant materials.MethodologyExtraction conditions of ...
Sebastian Granica, Agnieszka Bazylko, Anna K Kiss   +2 more
exaly   +3 more sources

Genotoxicity and cytotoxicity evaluation of oenothein B and its protective effect against mitomycin C-induced mutagenic action

Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2014
The natural product oenothein B (OeB), a dimeric macrocyclic ellagitannin, has a wide range of biological activities, such as antioxidant, anti-inflammatory, anti-viral, antifungal, and antitumor. However, investigations concerning its genotoxicity have not been carried out.
Jefferson Hollanda Veras, Lee Chen-Chen, Pedro Henrique Ferri   +2 more
exaly   +3 more sources

Induction of neutral endopeptidase activity in PC-3 cells by an aqueous extract of Epilobium angustifolium L. and oenothein B

Phytomedicine, 2006
An aqueous extract of Epilobium angustifolium and its main compound oenothein B (OeB), a dimeric macrocyclic ellagitannin, are specifically able to induce the neutral endopeptidase (NEP) in prostate cancer cells. The angiotensin-converting enzyme (ACE) is not influenced.
Anna K Kiss, M F Melzig
exaly   +3 more sources

Inhibition of 5α-Reductase and Aromatase by the Ellagitannins Oenothein A and Oenothein B fromEpilobiumSpecies

Planta Medica, 1997
Species of the genus Epilobium (Onagraceae) have been investigated for their activity against 5 alpha-reductase and aromatase, two enzymes which are involved in the aetiology of benign prostatic hyperplasia (BPH). Activity-guided fractionation has led to the identification of two macrocyclic ellagitannins, oenothein A (1) and oenothein B (2), as the ...
Ducrey B, Marston A, Göhring S, Hartmann RW, Hostettmann K   +4 more
openaire   +3 more sources

Stimulation and priming of innate lymphocytes by oenothein B (89.59)

The Journal of Immunology, 2010
Abstract Oenothein B is an immunomodulatory tannin isolated from the Epilobium angustifolium plant. This compound is known to affect myeloid cells and these effects include enhanced chemotaxis, NF-κB activation, and production of proinflammatory cytokines, including TNFα and IL-6. Its effects on other innate immune cells have not been
Andrew Ramstead, Igor Schepetkin, Mark Quinn, Mark Jutila   +3 more
openaire   +1 more source

Oenothein B, dimeric hydrolysable tannin inhibiting HCV invasion from Oenothera erythrosepala

Journal of Natural Medicines, 2018
The envelope proteins of the hepatitis C virus (HCV), E1 and E2, have been revealed to be essential for invasion of HCV. Thus, we were engaged in the search for the inhibitors against HCV invasion through the assay system using the model virus expressing recombinant HCV envelopes, E1 and E2. Now, we disclosed dimeric hydrolysable tannin oenothein B (1)
Satoru Tamura, Gang-Ming Yang, Teruaki Koitabashi, Yoshiharu Matsuura, Yasumasa Komoda, Tomikazu Kawano, Nobutoshi Murakami   +6 more
openaire   +2 more sources