Results 41 to 50 of about 12,682,152 (244)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Dispersion effects on performance of the free-electron laser FLASH

open access: yesPhysical Review Special Topics. Accelerators and Beams, 2010
This paper studies the impact of transverse dispersion on the free-electron laser (FEL) performance in two main aspects: radiation power sensitivity to electron beam energy offset and radiation wavelength spectrum.
Eduard Prat   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Offset-Free Strategy by Double-Layered Linear Model Predictive Control [PDF]

open access: yes, 2020
In the real applications, the model predictive control MPC technology is separated into two layers, that is, a layer of conventional dynamic controller, based on which is an added layer of steady-state target calculation.
Tao Zou
core  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Offset-free model predictive control for enhancing MR-HIFU hyperthermia in cancer treatment⁎

open access: yes, 2018
In this paper, an offset-free MPC scheme is developed to improve performance and robustness of temperature control in magnetic resonance-guided high-intensity focused ultrasound hyperthermia cancer treatments.
Heijman, E.   +6 more
core   +1 more source

Mitigating Vortex Splitting by Controlling the Wavefront Isophase Line Curvature of Vector Autofocusing Airy Vortex Beams in Free Space

open access: yesPhotonics, 2022
The match between the orbital angular momentum (OAM) transmission and receipt is a prerequisite for vortex beams as a carrier of the wireless optical communication system in free space.
Xu Yan, Shuang Liang, Jia Li, Lixin Guo
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Constrained MPC for a linear system to track time-varying reference signals

open access: yesMechanical Engineering Journal
This paper presents a model predictive control algorithm under input and state constraints. The algorithm is designed to track time-varying reference signals and allows for offset-free tracking when the reference signal is a constant or ramp signal.
Renlong WU, Nobutaka WADA
doaj   +1 more source

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