Results 101 to 110 of about 911,118 (353)

Population-level analyses identify host and environmental variables influencing the vaginal microbiome

Signal Transduction and Targeted Therapy
The vaginal microbiome is critical for the reproductive health of women, yet the differential impacts exerted by the host and by ambient environmental variables on the vaginal microbiome remain largely unknown.
Lang Qin, Tianyong Sun, Xiao Li, Shigang Zhao, Zheng Liu, Changlong Zhang, Congcong Jin, Yanqi Xu, Xuan Gao, Yongzhi Cao, Jiaojiao Wang, Ting Han, Lei Yan, Jialun Song, Fangfang Zhang, Feifei Liu, Yousheng Zhang, Yuzhen Huang, Yuping Song, Yanjun Liu, Jing Zhang, Xiuqing Zhang, Zhina Yao, Honglei Chen, Zhenzhen Zhang, Shengrui Zhao, Yuhan Feng, Ya-nan Zhang, Qian Yu, Fang Cao, Lijuan Zhao, Lei Xie, Ling Geng, Qiang Feng, Han Zhao, Zi-Jiang Chen   +35 more
doaj   +1 more source

EFFECT OF L- ARGININE SUPPLEMENTATION ON PRODUCTIVE, REPRODUCTIVE PERFORMANCE, IMMUNE RESPONSE AND GENE EXPRESSION IN TWO LOCAL CHICKEN STRAINS: 2- RESPONSES OF OFFSPRING. [PDF]

, 2016
R. Abou El-Ghar, S. Youssef
openalex   +1 more source

Review for "Phosphoproteomic profiling of the hippocampus of offspring rats exposed to prenatal stress"

, 2021

openalex   +1 more source

DOT1L Drives Endothelial‐to‐Mesenchymal Transition and Fibrotic Vascular Remodeling via H3K79 Methylation

Advanced Science, EarlyView.
DOT1L as a central epigenetic regulator of EndoMT and pulmonary fibrosis. Acting as an early epigenetic switch, it translates TGFβ–SMAD signaling into H3K79me2‐mediated chromatin remodeling, selectively activates fibrosis‐related genes, and primes ECs for rapid mesenchymal transition.
Yaofeng Wang, Xing Peng, Jingjing Chen, Yun Zhang, Tinghong Zhang, Jingyuan Zhang, Jiaying Fan, Hui Zheng, Qiaoyuan Liu, Zhimin Song, Zhan‐Peng Huang, Shu Meng   +11 more
wiley   +1 more source

Nano-zinc oxide (nZnO) targets the AMPK-ULK1 pathway to promote bone regeneration

Stem Cell Research & Therapy
Background Nano-zinc oxide (nZnO) has attracted significant attention in bone tissue engineering due to its antibacterial properties, anti-inflammatory effects, biocompatibility, and chemical stability.
Xiu Chen, Zhenkun Weng, Hongchao Zhang, Jian Jiao, Jingjia Liang, Jin Xu, Dongmei Wang, Qian Liu, Qing Yan, Aihua Gu   +9 more
doaj   +1 more source

Large deviation results for Critical Multitype Galton-Watson trees

, 2016
In this article, we prove a joint large deviation principle in $n$ for the \emph{empirical pair measure} and \emph{ empirical offspring measure} of critical multitype Galton-Watson trees conditioned to have exactly $n$ vertices in the weak topology. From
Doku-Amponsah, Kwabena
core   +1 more source

Embedded CRISPRi Enhances Gene‐Silencing Efficiency in Drosophila

Advanced Science, EarlyView.
Current CRISPR interference (CRISPRi) technology in Drosophila has limited efficiency. This study introduces the emCRISPRi platform, which significantly enhances transcriptional silencing efficacy by embedding inhibitory domains within the dCas9 architecture.
Pengchong Fu, Xuedi Zhang, Ying Zhou, Jie Zheng, Angyang Sun, Kailong Zhuang, Weiwei Bao, Guanjun Gao   +7 more
wiley   +1 more source

Inter- and trans-generational impacts of real-world PM2.5 exposure on male-specific primary hypogonadism

Cell Discovery
Exposure to PM2.5, a harmful type of air pollution, has been associated with compromised male reproductive health; however, it remains unclear whether such exposure can elicit transgenerational effects on male fertility.
Xiaoyu Wei, Zhonghao Zhang, Yayun Gu, Rong Zhang, Jie Huang, Feng Li, Yuanlin He, Shuai Lu, Yifei Wu, Wentao Zeng, Xiaorui Liu, Chenzi Liu, Jinyi Liu, Lin Ao, Fuquan Shi, Qing Chen, Yuan Lin, Jiangbo Du, Guangfu Jin, Yankai Xia, Hongxia Ma, Yuxin Zheng, Ran Huo, Jia Cao, Hongbing Shen, Zhibin Hu   +25 more
doaj   +1 more source

A Testis‐Specific Aralkylamine N‐Acetyltransferase Regulates Dimorphic Sperm Function and Male Fertility in Moths

Advanced Science, EarlyView.
We identify a Lepidoptera‐conserved testis‐specific arylalkylamine N‐acetyltransferase (LTNAT) that governs male moth fertility via a novel mechanism. LTNAT loss disrupts eupyrene sperm mitochondrial derivatives and impairs apyrene sperm motility, offering a safe molecular target for innovative pesticides and genetic pest control.
Hao Sun, Peng‐Yi Huang, Zhi‐Ruo Zhang, Cong‐Fen Gao, Subba Reddy Palli, Shun‐Fan Wu   +5 more
wiley   +1 more source

The ARCCRABP1 neurons play a crucial role in the regulation of energy homeostasis

Nature Communications
Recent single-cell RNA sequencing study suggested that CRABP1 expressing neurons in the arcuate nucleus (ARCCRABP1 neurons) were a distinct group of neurons. However, the physiological role of ARCCRABP1 neurons remains unexplored.
Lihong Yan, Xin Zhang, Liling Jin, Yin Li, Yang Chen, Jubiao Zhang, Zhenning Sun, Junxia Qi, Changqing Qu, Guanzhong Dong, Yongjie Zhang, Qin Jiang, An Liu, Juxue Li   +13 more
doaj   +1 more source