Neural Plasticity, 2021 As a classical growth promoter and metabolic regulator, growth hormone (GH) is involved in development of the central nervous system (CNS). This hormone might also act as a neurotrophin, since GH is able to induce neuroprotection, neurite growth, and ...
Juan David Olivares-Hernández +5 more
doaj +1 more source
Combined Cyclosporin A and Hypothermia Treatment Inhibits Activation of BV-2 Microglia but Induces an Inflammatory Response in an Ischemia/Reperfusion Hippocampal Slice Culture Model [PDF]
, 2019 Introduction: Hypothermia attenuates cerebral ischemia-induced neuronal cell death associated with neuroinflammation. The calcineurin inhibitor cyclosporin A (CsA) has been shown to be neuroprotective by minimizing activation of inflammatory pathways.
Berger, Felix +5 more
core +1 more source
Cell Death and Disease, 2022 Acute ischemic stroke (AIS) is a global cerebrovascular disease with high disability and mortality, which has no effective therapy. Studies have demonstrated that astrocyte-derived exosomes (ADEXs) provided neuroprotection in experimental stroke models ...
Yang Deng +7 more
doaj +1 more source
NEUROPROTECTIVE EFFECTS AND MECHANISM OF CMS121 IN A NEURON MODEL OF OXYGEN-GLUCOSE DEPRIVATION/REPERFUSION AND A MOUSE MODEL OF ISCHEMIA-REPERFUSION [PDF]
精准医学杂志, 2023 Objective To investigate the neuroprotective effects and mechanism of CMS121 in a neuron model of oxygen-glucose deprivation/reperfusion (OGD/R) and a mouse model of ischemia/reperfusion (I/R).
ZHAO Zhiyuan, ZHAO Rui, LIU Wenhao, SUN Chengjian, XU Rui
doaj +1 more source
Time trend occurrence of duodenal intraepithelial lymphocytosis and celiac disease in an open access endoscopic population [PDF]
, 2017 Background: Duodenal intraepithelial lymphocytosis (DIL) is a histological finding characterized by the increase of intraepithelial CD3T-lymphocytes over the normal value without villous atrophy, mostly associated to coeliac disease (CD), Helicobacter ...
Annibale, B. +7 more
core +2 more sources
Quasi-Delay-Insensitive Circuits are Turing-Complete [PDF]
, 1995 Quasi-delay-insensitive (QDI) circuits are those whose correct operation does not depend on the delays of operators or wires, except for certain wires that form isochronic forks.
Manohar, Rajit, Martin, Alain J.
core +5 more sources
Sulforaphane (SFA) protects neuronal cells from oxygen & glucose deprivation (OGD)
PLOS ONE, 2021 Background Perinatal brain injury results in neurodevelopmental disabilities (neuroDDs) that include cerebral palsy, autism, attention deficit disorder, epilepsy, learning disabilities and others. Commonly, injury occurs when placental circulation, that is responsible for transporting nutrients and oxygen to the fetus, is compromised.
Zeenat Ladak +6 more
openaire +4 more sources
Frontiers in Neuroscience, 2019 Reopening of the cerebral artery after occlusion often results in “no-reflow” that has been attributed to the death and contraction (rigor mortis) of pericytes.
Mohammed Heyba +5 more
doaj +1 more source
The spectrum of Ischemia-induced white matter injury varies with age [PDF]
, 2013 Stroke is a neurological condition that targets the whole range of the human population, from the pre-term infant to the elderly and is a major cause of death worldwide (Ingall 2004).
Muscat, Richard +2 more
core +1 more source
HUWE1 E3 ligase promotes PINK1/PARKINindependent mitophagy by regulating AMBRA1 activation via IKKa [PDF]
, 2018 The selective removal of undesired or damaged mitochondria by autophagy, known as mitophagy, is crucial for cellular homoeostasis, and prevents tumour diffusion, neurodegeneration and ageing.
A Criollo +70 more
core +4 more sources