Results 21 to 30 of about 14,327 (215)

Surgical OGD – a dying art? [PDF]

open access: yesAnnals of The Royal College of Surgeons of England, 2003
Reductions in surgical training and the increases in medical gastroenterology have raised concerns that surgeons may not be adequately trained in upper gastrointestinal (GI) endoscopy.To evaluate this problem, a questionnaire was sent to all current surgical specialist registrars (SpRs) in the South Thames East Region.There was an 82% (52/63) response ...
R E, Bell, N J, Griffiths, T, Bates
openaire   +2 more sources

Mechanistic modeling of drug products applied to the skin: A workshop summary report

open access: yesCPT: Pharmacometrics & Systems Pharmacology, 2023
The development of a generic drug product involves demonstrating that there is no significant difference in the rate and extent to which the active ingredient becomes available at the site of action, relative to the reference listed drug product.
Eleftheria Tsakalozou   +9 more
doaj   +1 more source

Factors Influencing the Effectiveness of Open Government Data Platforms: A Data Analysis of 61 Prefecture-Level Cities in China

open access: yesSAGE Open, 2023
Information disclosure, participatory governance, and collaborative innovation are open government data’s (OGD) main goals. Understanding the preconditions that enable the efficient and effective implementation of OGD initiatives is essential for ...
Jinhua Chu, You-Yu Dai, Anyuan Zhong
doaj   +1 more source

Factors Influencing Citizens’ Intention to Use Open Government Data—A Case Study of Pakistan

open access: yesBig Data and Cognitive Computing, 2022
Open government data (OGD) has gained much attention worldwide; however, there is still an increasing demand for exploring research from the perspective of its adoption and diffusion.
Muhammad Mahboob Khurshid   +5 more
doaj   +1 more source

Shared signaling pathway in pyroptosis and apoptosis in A549 cells induced by oxygen and glucose deprivation/recovery

open access: yes陆军军医大学学报, 2022
Objective To investigate the effects of oxygen and glucose deprivation/recovery (OGD/R) on apoptosis and pyroptosis of A549 cells, and to explore the possibility of the mutual regulation in apoptosis and pyroptosis.
AN Yuxuan   +5 more
doaj   +1 more source

Resveratrol promotes the polarization of rat microglial cell line to M2 type with oxygen glucose deprivation/reoxygenation via up-regulating the expression of annexin A1 [PDF]

open access: yesJichu yixue yu linchuang, 2021
Objective To explore the role of annexin A1 (ANXA1) in resveratrol regulation of M2 type polarization of rat microglial cell line with oxygen glucose deprivation/reoxygenation (OGD/R) model.
LIN Min, ZHANG Hong-mei
doaj  

Kaempferol Ameliorates Oxygen-Glucose Deprivation/Reoxygenation-Induced Neuronal Ferroptosis by Activating Nrf2/SLC7A11/GPX4 Axis

open access: yesBiomolecules, 2021
Kaempferol has been shown to protect cells against cerebral ischemia/reperfusion injury through inhibition of apoptosis. In the present study, we sought to investigate whether ferroptosis is involved in the oxygen-glucose deprivation/reperfusion (OGD/R ...
Yuan Yuan   +4 more
doaj   +1 more source

Study of endoplasmic reticulum stress in human dental pulp cells induced by oxygen-glucose deprivation culture in vitro

open access: yes口腔疾病防治, 2022
Objective Oxygen-glucose deprivation (OGD) is used to mimic ischemia in vitro to observe whether endoplasmic reticulum (ER) stress is involved in human dental pulp cells (hDPCs) after OGD and to better understand the regulatory mechanism of hDPCs in ...
LI Lifen, ZHU Yaqin, JIANG Long
doaj   +1 more source

Growth Hormone (GH) Enhances Endogenous Mechanisms of Neuroprotection and Neuroplasticity after Oxygen and Glucose Deprivation Injury (OGD) and Reoxygenation (OGD/R) in Chicken Hippocampal Cell Cultures

open access: yesNeural Plasticity, 2021
As a classical growth promoter and metabolic regulator, growth hormone (GH) is involved in development of the central nervous system (CNS). This hormone might also act as a neurotrophin, since GH is able to induce neuroprotection, neurite growth, and ...
Juan David Olivares-Hernández   +5 more
doaj   +1 more source

Astrocyte-derived exosomal nicotinamide phosphoribosyltransferase (Nampt) ameliorates ischemic stroke injury by targeting AMPK/mTOR signaling to induce autophagy

open access: yesCell Death and Disease, 2022
Acute ischemic stroke (AIS) is a global cerebrovascular disease with high disability and mortality, which has no effective therapy. Studies have demonstrated that astrocyte-derived exosomes (ADEXs) provided neuroprotection in experimental stroke models ...
Yang Deng   +7 more
doaj   +1 more source

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