Results 31 to 40 of about 14,327 (215)

NEUROPROTECTIVE EFFECTS AND MECHANISM OF CMS121 IN A NEURON MODEL OF OXYGEN-GLUCOSE DEPRIVATION/REPERFUSION AND A MOUSE MODEL OF ISCHEMIA-REPERFUSION [PDF]

精准医学杂志, 2023
Objective To investigate the neuroprotective effects and mechanism of CMS121 in a neuron model of oxygen-glucose deprivation/reperfusion (OGD/R) and a mouse model of ischemia/reperfusion (I/R).
ZHAO Zhiyuan, ZHAO Rui, LIU Wenhao, SUN Chengjian, XU Rui
doaj   +1 more source

Sulforaphane (SFA) protects neuronal cells from oxygen & glucose deprivation (OGD)

PLOS ONE, 2021
Background Perinatal brain injury results in neurodevelopmental disabilities (neuroDDs) that include cerebral palsy, autism, attention deficit disorder, epilepsy, learning disabilities and others. Commonly, injury occurs when placental circulation, that is responsible for transporting nutrients and oxygen to the fetus, is compromised.
Zeenat Ladak, Elizabeth Garcia, Jenny Yoon, Takaaki Landry, Edward A. Armstrong, Jerome Y. Yager, Sujata Persad   +6 more
openaire   +4 more sources

Viability and Contractility of Rat Brain Pericytes in Conditions That Mimic Stroke; an in vitro Study

Frontiers in Neuroscience, 2019
Reopening of the cerebral artery after occlusion often results in “no-reflow” that has been attributed to the death and contraction (rigor mortis) of pericytes.
Mohammed Heyba, Lulwa Al-Abdullah, Andreas W. Henkel, Zeinab Sayed, Slava A. Malatiali, Zoran B. Redzic   +5 more
doaj   +1 more source

Contribution of ginsenosides Rg1, Rb1 to the neuroprotective effect of Panax notoginseng in mouse organotypic hippocampal slice cultures exposed to oxygen and glucose deprivation

Vietnam Journal of Science, Technology and Engineering, 2022
We previously demonstrated that Panax notoginseng (pNG) root extract treatments exerted neuroprotective effects on brain injuries using middle cerebral artery occlusion in mice.
Nguyen Thi Thanh Loan, Le Thi Xoan, Pham Thi Nguyet Hang, Nguyen Van Tai   +3 more
doaj   +1 more source

Metadata quality matters in Open Government Data (OGD) evaluation! An empirical investigation of OGD portals of the GCC constituents

Transforming Government: People, Process and Policy, 2023
Purpose: The study seeks to investigate the quality of metadata associated with the open government data (OGD) portals of the six Gulf Cooperation Council (GCC) constituents – Bahrain (BH), Kuwait (KW), Oman (OM), Qatar (QA), Kingdom of Saudi Arabia (KSA) and United Arab Emirates (UAE).
Chokki, Abiola Paterne, Alexopoulos, Charalampos, Saxena, Stuti, Frénay, Benoît, Vanderose, Benoit, Ali, Mohsan   +5 more
openaire   +1 more source

Apelin-13 Protects Neurons by Attenuating Early-Stage Postspinal Cord Injury Apoptosis In Vitro

Brain Sciences, 2022
Apelin is a 77-amino-acid peptide that is an endogenous ligand for the G protein-coupled receptor APJ (Apelin receptor, APJ). Apelin-13, as the most bioactive affinity fragment of apelin, plays a role in energy metabolism, myocardial ischemia-reperfusion
Taotao Lin, Yujie Zhao, Shengyu Guo, Zhengru Wu, Wenwen Li, Rongcan Wu, Zhenyu Wang, Wenge Liu   +7 more
doaj   +1 more source

Gp91phox (NOX2) in Activated Microglia Exacerbates Neuronal Damage Induced by Oxygen Glucose Deprivation and Hyperglycemia in an in Vitro Model

Cellular Physiology and Biochemistry, 2018
Background/Aims: Peri-operative cerebral ischemia reperfusion injury is one of the most serious peri-operative complications that can be aggravated in patients with diabetes.
Xianzhang Zeng, Hongliang Ren, Yana Zhu, Ruru Zhang, Xinxin Xue, Tao Tao, Hongjie Xi   +6 more
doaj   +1 more source

Brain-derived neurotrophic factor mediates macrophage migration inhibitory factor to protect neurons against oxygen-glucose deprivation

Neural Regeneration Research, 2020
Macrophage migration inhibitory factor (MIF) is a chemokine that plays an essential role in immune system function. Previous studies suggested that MIF protects neurons in ischemic conditions.
Su Hwan Bae, Mi Ran Yoo, Ye Yeong Kim, In Kyung Hong, Mi Hee Kim, Seung Hak Lee, Dae Yul Kim   +6 more
doaj   +1 more source

In vitro model of ischemic stroke neurons from Macaca fascicularis

Open Veterinary Journal
Background: Primary cells have the same heterogeneity and differentiation capacity that has potential as an in vitro ischemic stroke models. It is hoped that primary cells from non-human primates/NHPs that have genetic similarities to humans can provide
Ratih Rinendyaputri, Sela Septima Mariya, Frans Dany, Ariyani Noviantari, Dwi Budiono, Lisa Andriani Lienggonegoro, Hasta Handayani Idrus, Wireni Ayuningtyas, Rachmawati Noverina, Fathul Huda, Ahmad Faried   +10 more
doaj   +1 more source

OGD Heartbeat: Cities’ Commitment to Open Data

JeDEM - eJournal of eDemocracy and Open Government, 2015
This paper develops and tests a theoretical model, which proposes to examine cities’ commitment to the concept of open government data (OGD) according to three typical levels. Level 1, Way of Life, indicates high commitment to OGD; Level 2, On the Fence, represents either a low or erratic commitment; Level 3, Lip Service, refers to either scarce or no ...
Karin Nahon, Alon Peled, Jenniver Shkabatur   +2 more
openaire   +2 more sources