Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Emulsifaction of waste cooking oils and fatty acid distillates as diesel engine fuel [PDF]
The scope of this paper is to analyze the possibilities and feasibilities, as well as the main experimental results reported about the emulsification method applied to waste cooking oils and fatty acid distillates as diesel engine fuels, compared with ...
Goyos-Pérez, Leonardo +3 more
core +1 more source
Detection of hydrocarbon contaminants in groundwater systems [PDF]
We present a study of groundwater contaminants from infiltration of heavy hydrocarbon pollution sources. This study primarily focuses on the volatile and non-volatile components of crude and processed oils.
Iceman, Christopher +3 more
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Optimum conditions for enzymatic degradation of some oilseed proteins
Soybean, sesame seed, and rice bran meal proteins were hydrolyzed with two enzymes, namely, papain and bromelain. Experiments were carried out to elucidate the optimum condition for each enzyme when acting on each substrate seperately.
F. S. Taha +2 more
doaj +1 more source
Flow behaviour of dielectric liquids in an electric field [PDF]
A family of 10 silicone oils with electrical conductivity similar to 10(-13) S m(-1) (a regime hitherto systematically unexplored) and viscosities ranging from 1 to 2000mPas have been Subjected to an electrical field of up to 1.5kV mm(-1) during flow ...
Edirisinghe, MJ +2 more
core +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Studies on cocoa butter-replacer mixtures suitable for the local chocolate production.
Mixtures of cocoa butter with different replacers, added at different levels, were prepared. From their properties, and particularly solid fat index, helped much in selecting the more suitable mixture for local chocolate production.
M. Hassan El-Mallah, M. G. Megahed
doaj +1 more source
Detection of antibacterial activity of essential oil components by TLC-bioautography using luminescent bacteria [PDF]
The aim of the present study was the chemical characterization of some medically relevant essential oils (tea tree, clove, cinnamon bark, thyme and eucalyptus) and the investigation of antibacterial effect of the components of these oils by use of a ...
Adams R.P. +35 more
core +1 more source

