Results 11 to 20 of about 2,695,498 (213)
Okadaic Acid: A Tool to Study the Hippo Pathway [PDF]
Marine Drugs, 2013 Mammalian Ste20-like kinases 1 and 2 (MST1 and MST2) are activated in NIH3T3 cells exposed to okadaic acid. The Hippo pathway is a newly emerging signaling that functions as a tumor suppressor.
Yutaka Hata +2 more
doaj +4 more sources
Identification of Dynamic Changes in Proteins Associated with the Cellular Cytoskeleton after Exposure to Okadaic Acid [PDF]
Marine Drugs, 2013 Exposure of cells to the diarrhetic shellfish poison, okadaic acid, leads to a dramatic reorganization of cytoskeletal architecture and loss of cell-cell contact.
Peter Roepstorff +5 more
doaj +2 more sources
Toxins, 2018 Mycotoxins are emerging toxins in the marine environment, which can co-occur with algal toxins to exert synergistic or antagonistic effects for human seafood consumption.
Aiko Hayashi +3 more
doaj +3 more sources
Screening for Okadaic Acid by Immunoassay
Journal of AOAC INTERNATIONAL, 1995 Abstract Increasing incidences of phytoplankton blooms with the potential danger of toxin release into the food chain have necessitated the search for new diagnostic methods that can detect toxins quickly and reliably. A competitive enzymelinked immunosorbent assay (ELISA) was developed to quantitate okadaic acid in shellfish and ...
Chin, J. D. +4 more
openaire +4 more sources
Toxins, 2013 In vivo, after administration by gavage to mice and rats, okadaic acid has been reported to produce lesions in liver, small intestine and forestomach.
Luis M. Botana +9 more
doaj +2 more sources
Diverse Bacterial PKS Sequences Derived From Okadaic Acid-Producing Dinoflagellates [PDF]
Marine Drugs, 2008 Okadaic acid (OA) and the related dinophysistoxins are isolated from dinoflagellates of the genus Prorocentrum and Dinophysis. Bacteria of the Roseobacter group have been associated with okadaic acid producing dinoflagellates and have been previously ...
Kathleen S. Rein +4 more
doaj +2 more sources
Identification of 19-epi-okadaic Acid, a New Diarrhetic Shellfish Poisoning Toxin, by Liquid Chromatography with Mass Spectrometry Detection [PDF]
Marine Drugs, 2008 Okadaic acid (1) (OA) and its congeners are mainly responsible for diarrhetic shellfish poisoning (DSP) syndrome. The presence of several OA derivatives have already been confirmed in Prorocentrum and Dinophysis spp.
José J. Fernández +5 more
doaj +2 more sources
Health Risk Assessment of Okadaic Acid and Domoic Acid in Some Edible Bivalves from Hormozgan Province in the North of Persian Gulf [PDF]
Pollution, 2022 The biotoxins can enter the marine food chain, and, accordingly, seafood consumers are also at risk of ingesting toxins from contaminated aquatic animals.
Seyedeh Laili Mohebbi-Nozar +3 more
doaj +1 more source
Serine/Threonine Protein Phosphatase 2A Regulates the Transport of Axonal Mitochondria
Frontiers in Cellular Neuroscience, 2022 Microtubule-based transport provides mitochondria to distant regions of neurons and is essential for neuronal health. To identify compounds that increase mitochondrial motility, we screened 1,641 small-molecules in a high-throughput screening platform ...
Keunjung Heo +11 more
doaj +1 more source
High Value Phycotoxins From the Dinoflagellate Prorocentrum
Frontiers in Marine Science, 2021 Marine dinoflagellates produce chemically diverse compounds, with a wide range of biological activity (antimicrobial, anticancer, treatment of neurodegenerative disease along with use as biomedical research tools).
Dolores Camacho-Muñoz +3 more
doaj +1 more source