Results 41 to 50 of about 2,519,072 (211)
Numerous toxin-producing harmful algal (HAB) species occur in Florida's coastal waters. Exposure to these toxins has been shown to have sublethal effects in sea turtles.
Justin R. Perrault +5 more
doaj +1 more source
2D nanosheets, with large surface area, excellent optical/electrical properties, and high specificity, combine with lateral flow assay strips to enable rapid, readable detection, boosting the strips’ development and applications. Abstract Lateral flow assays (LFAs) are widely used for point‐of‐care diagnostics, but their detection capability remains ...
Weimin Xu +11 more
wiley +1 more source
Transformation of a marine toxic polyether, okadaic acid. [PDF]
Natural okadaic acid 1 was transformed into the 7, 24, 27-tri-0-benzyl-l, 2-acetonide derivative (4) in a 66% overall yidd. The corresponding synthetic derivative (4) was identified with this authentic sample.
ICHIKAWA, Yoshiyasu +2 more
openaire +2 more sources
Electrochemical aptasensors are emerging as powerful platforms for precision diagnostics and environmental monitoring, owing to their high selectivity, programmability and compatibility with miniaturised systems. However, their broader application is constrained by limited signal intensity and challenges in reliable multiplexed detection.
Azadeh Abdi +5 more
wiley +1 more source
Phosphorylation of BigH1 regulates its expression pattern and promotes embryonic development
Phosphorylation is a key regulator of the linker histone variant BigH1 during Drosophila embryogenesis. We reveal that N‐terminal phosphorylation promotes the timely removal of BigH1 from chromatin. In contrast, C‐terminal phosphorylation supports early nuclear divisions and embryonic viability.
Ramóna Pék +9 more
wiley +1 more source
Oysters (Crassostrea virginica) were screened for 12 phycotoxins over two years in nearshore waters to collect baseline phycotoxin data and to determine prevalence of phycotoxin co-occurrence in the commercially and ecologically-relevant species.
Sarah K.D. Pease +12 more
doaj +1 more source
Abstract This study investigated Prangos ferulacea (PF)‐induced hepatotoxicity, its potential association with endoplasmic reticulum (ER) stress and proinflammatory cytokines, and the effect of the cannabinoid type 2 receptor agonist JWH‐133. Rats (n = 37) were divided into four groups: control–sham group (CSG, n = 9), PF extract group (PG, n = 9), PF ...
Mesut Çelik +7 more
wiley +1 more source
Isoproterenol-induced dephosphorylation events in the presence of okadaic acid.
MEFs were pretreated with okadaic acid (1 μM) for 30 minutes and then were stimulated with isoproterenol (10 μM) for various times (0, 5, 10, 20, 30, or 60 minutes).
Steven M. Chan (493709) +3 more
core +1 more source
A rapid competitive ELISA assay of Okadaic acid level based on epoxy-functionalized magnetic beads
Using newly designed epoxy group activated carbon shell magnetic beads as a goat against mouse antibody (G-Mab) carrier, a competitive immunoassay was conducted on the surface of G-Mab-coated magnetic beads (G-Mab-MBs).
Linjiang Pang +8 more
doaj +1 more source
Marine toxins and the cytoskeleton: okadaic acid and dinophysistoxins [PDF]
Okadaic acid (OA) and its analogs, the dinophysistoxins, are potent inhibitors of protein phosphatases 1 and 2A. This action is well known to cause diarrhea and gastrointestinal symptons when the toxins reach the digestive tract by ingestion of mollusks. A less well‐known effect of these group of toxins is their effect in the cytoskeleton.
Carmen, Vale, Luis M, Botana
openaire +2 more sources

