Results 41 to 50 of about 14,228 (214)
Permeability characteristics of erythrocyte membrane to okadaic acid and calyculin A [PDF]
The rates of transport of the protein phosphatase inhibitors okadaic acid and calyculin A through rabbit erythrocyte membranes have been estimated by measuring protein phosphatase type 2A (PP2A) activity in lysates.
M. L. Jennings, A. N. Namboodiripad
core +1 more source
19-epi-Okadaic Acid, a Novel Protein Phosphatase Inhibitor with Enhanced Selectivity [PDF]
A new protein phosphatase inhibitor, 19-epi-okadaic acid, was isolated from the marine dinoflagellate Prorocentrum belizeanum. Its structure and conformation in solution has been determined, and important differences were found when compared with the ...
Hernández Daranas, Antonio +3 more
core +1 more source
Porous Organic Polymers: From Molecular Design to Scalable Technologies
This review introduces porous organic polymers (POPs) for a wide range of applications, including energy storage, gas adsorption, catalysts, adsorbents, biomedical applications, sensors, and other exciting fields, and critically analyzes the synthesis and modification, and how structural topology influences the composites' architecture of POPs, along ...
Hossein Mashhadimoslem +12 more
wiley +1 more source
Mass Spectral Characterisation of Three New Groups of Algal Toxins [PDF]
This thesis reports the mass spectral identification and characterisation of three new groups of algal compounds. A series of novel pectenotoxins (PTXs) were identified in retained sub-samples of Irish mussel extracts that had previously been utilised ...
Knudsen, Brent Kevin
core
Effect of okadaic acid on histamine release from rat peritoneal mast cells activated by anti-IgE [PDF]
The effect of okadaic acid, a potent inhibitor of protein phosphatase 1 and 2A, on histamine release from mast cells has been investigated. Okadaic acid strongly and dose-dependently inhibited histamine release from mast cells induced by anti-IgE.
Koichi Endo, Masao Takei, Hideki Mitsui
core +1 more source
2D nanosheets, with large surface area, excellent optical/electrical properties, and high specificity, combine with lateral flow assay strips to enable rapid, readable detection, boosting the strips’ development and applications. Abstract Lateral flow assays (LFAs) are widely used for point‐of‐care diagnostics, but their detection capability remains ...
Weimin Xu +11 more
wiley +1 more source
Marine toxins and the cytoskeleton: okadaic acid and dinophysistoxins [PDF]
Okadaic acid (OA) and its analogs, the dinophysistoxins, are potent inhibitors of protein phosphatases 1 and 2A. This action is well known to cause diarrhea and gastrointestinal symptons when the toxins reach the digestive tract by ingestion of mollusks. A less well‐known effect of these group of toxins is their effect in the cytoskeleton.
Carmen, Vale, Luis M, Botana
openaire +2 more sources
19-epi-Okadaic Acid, a Novel Protein Phosphatase Inhibitor with Enhanced Selectivity [PDF]
A new protein phosphatase inhibitor, 19-epi-okadaic acid, was isolated from the marine dinoflagellate Prorocentrum belizeanum. Its structure and conformation in solution has been determined, and important differences were found when compared with the ...
Antonio Hernández Daranas (2473177) +3 more
core +1 more source
Numerous toxin-producing harmful algal (HAB) species occur in Florida's coastal waters. Exposure to these toxins has been shown to have sublethal effects in sea turtles.
Justin R. Perrault +5 more
doaj +1 more source
Abstract figure legend Catecholaminergic polymorphic ventricular tachycardia (CPVT) variants in N terminal (NTD) and central domain (CD) but not pore domain induce a pathological RyR2 conformational shift upon protein kinase A (PKA) phosphorylation, similar to that seen in heart failure (HF), calcium/calmodulin‐dependent protein kinase II (CaMKII ...
Hitoshi Uchinoumi +11 more
wiley +1 more source

