Results 61 to 70 of about 2,813,688 (177)
Ecotoxicology and Environmental SafetyOkadaic acid (OA), a diarrhetic shellfish toxin, causes significant intestinal and systemic toxicity. Currently, there are no approved therapeutics specifically targeting OA-induced diarrhea.
Ji-qian-zhu Zhang +9 more
doaj +1 more source
Marine Drugs, 2013 Okadaic Acid (OA) constitutes the main active principle in Diarrhetic Shellfish Poisoning (DSP) toxins produced during Harmful Algal Blooms (HABs), representing a serious threat for human consumers of edible shellfish.
José M. Eirín-López +8 more
doaj +1 more source
Aquatic Biology, 2020 We aimed to study the growth and toxicity responses of non-toxic (CCMP683) and toxic (CCMP2804) strains of Prorocentrum hoffmannianum under various nitrate and phosphate concentrations.
Lee, TCH, Chan, PL, Xu, SJL, Lee, FWF
doaj +1 more source
Cell Proliferation, Volume 59, Issue 3, March 2026.Maternal TCF12 ensures the competence of fertilisation by controlling the expression of Astl and the proper location of cortical granules. Furthermore, maternal TCF12 maintains the phosphatase activity of PP2A by regulating the expression of Arpp19. Oocyte‐specific deletion of Tcf12 leads to fertilisation defects as well as ZGA failure at the 2‐cell ...
Lan‐Rui Cao +7 more
wiley +1 more source
Estudo da frequência de hemócitos micronucleados, induzidos pelo ácido ocadáico, em mexilhões Perna perna (Mollusca : Bivalvia) / [PDF]
, 2000 Dissertação (Mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico.Algumas toxinas presentes naturalmente no ambiente marinho são capazes de induzir mutagenicidade e/ou carcinogenicidade.
Silva, Cátia Regina
core
Okadaic acid activates Wnt/β-catenin-signaling in human HepaRG cells
, 2019 The lipophilic phycotoxin okadaic acid (OA) occurs in the fatty tissue and hepatopancreas of filter-feeding shellfish. The compound provokes the diarrhetic shellfish poisoning (DSP) syndrome after intake of seafood contaminated with high levels of the ...
Dietrich, Jessica +8 more
core +1 more source
Self-Association of Okadaic Acid upon Complexation with Potassium Ion
, 2016 Okadaic acid (OA) is a toxin responsible for diarrhetic shellfish poisoning and is an extremely useful tool for studying processes that are regulated by phosphorylation, although the exact mechanism of action is still undetermined.
José A. Gavín (2727850) +4 more
core +1 more source
Advanced Science, Volume 13, Issue 6, 30 January 2026.Prenatal dexamethasone exposure (PDE) persistently upregulates hepatic CYP3A1/CYP2B1 in offspring via glucocorticoid receptor (GR) activation. In vivo and in vitro studies show GR promotes P300/CBP binding to the constitutive androstane receptor (CAR) promoter, sustaining histone acetylation (H3K9/K27ac) and enhancing CYP expression. The GR–CAR pathway
Xiaoxiang Sun +9 more
wiley +1 more source
, 2015 The ingestion of seafood contaminated with the marine biotoxin okadaic acid (OA) can lead to diarrhetic shellfish poisoning with symptoms like nausea, vomiting and abdominal cramps.
Lampen, Alfonso +5 more
core +1 more source
Marine Drugs, 2013 Harmful Algal Blooms (HABs) constitute one of the most important sources of contamination in the oceans, producing high concentrations of potentially harmful biotoxins that are accumulated across the food chains.
José M. Eirín-López +3 more
doaj +1 more source