Results 111 to 120 of about 56,178 (231)

Exploring Current Emergency Medical Services Approaches to Manage Agitated Older Adult Patients: An Analysis of Statewide Protocols

Journal of the American Geriatrics Society, EarlyView.
Most state EMS protocols provide guidance on management of agitated patients, including use of physical restraints and chemical sedatives, yet older adult‐specific modifications or dosing guidance are uncommon. ABSTRACT Background Agitation in older adults presents unique challenges for emergency medical services (EMS) clinicians.
Joshua Lachs, Rana Barghout, William Haussner, David Hancock, Emily Benton, Maia Dorsett, Gregory Peters, Rebecca Cash, Joseph Holley, Tony Rosen   +9 more
wiley   +1 more source

Triggers, Responses, and Outcomes for Patient Related Violence and/or Aggression Events During Acute Hospitalisation: A Documentary Analysis

Journal of Clinical Nursing, EarlyView.
ABSTRACT Aim To examine triggers, responses, and outcomes for patient‐related violence and/or aggression events during acute hospitalisation. Design This was a descriptive observational study undertaken at two healthcare organisations. Methods Pre‐existing data were extracted from organisational incident reports and individual medical records during a ...
Debra Kerr, Alison M. Hutchinson, Elisa Ilarda, Louise Alexander, Susan Perlen, Nicole Davies, Trish Mant, Angela Skazlic, Joanna Petrunic, Rachel Mrhar, Adam Searby   +10 more
wiley   +1 more source

A comparative study of olanzapine versus asenapine in acute treatment of manic episode: A 3-week prospective study

Journal of Mental Health and Human Behaviour, 2014
Introduction: Treatment of bipolar disorders has evolved over the years from conventional mood stabilizers to second-generation antipsychotics. Among the atypical antipsychotics, few have been approved by Food and Drug Administration as treatment of ...
Ajeet Sidana, Prannay Gulati, B S Chavan
doaj   +1 more source

Parasomnias and sleep‐related movement disorders induced by drugs in the adult population: a review about iatrogenic medication effects

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont, Vanessa Bloch, Agnès Lillo‐Lelouet, Christine Le Beller, Pierre A. Geoffroy, Marc Veyrier   +5 more
wiley   +1 more source

Pilot Study of Behavioral Activation Treatment for Negative Symptoms in Older Adults With Schizophrenia Spectrum Disorder

Psychiatric Research and Clinical Practice, EarlyView.
Objective Behavioral activation (BA) is an established treatment for depression in older adults, yet BA has been relatively less examined as a treatment for the negative symptoms (NS) of schizophrenia spectrum disorder (SSD). We here aimed to demonstrate the feasibility and proof‐of‐concept that BA can improve NS and function in older adults with SSD ...
Stephen F. Smagula, Jessica M. Gannon, Fabio Ferrarelli   +2 more
wiley   +1 more source

Oppositional Defiant Disorder and Aggression in a Young Man with Mental Retardation: Long-Term Treatment in a Community-Based Setting [PDF]

, 2008
A longitudinal, intensive treatment program is described that was implemented over an 8-year period in a community-based setting for a young man with mental retardation and oppositional defiant disorder with severe physical aggression. The development of
Barcelona, Amber L., Fox, Robert A., Holtz, Casey A.   +2 more
core   +1 more source

Learning Outcomes That Maximally Differentiate Psychiatric Treatments

International Journal of Methods in Psychiatric Research, Volume 35, Issue 2, June 2026.
ABSTRACT Objectives To develop a statistical method that uncovers clinically meaningful differences between active psychiatric treatments, even when traditional rating scales fail to do so. Methods We introduce Supervised Varimax (SV), a novel algorithm that transforms individual items from clinical rating scales into a small set of optimized outcomes ...
Eric V. Strobl, Semmie Kim
wiley   +1 more source

Associations Between Serum Adipokine, Antipsychotic Exposure, and Clinical Characteristics in Chronic Schizophrenia: A Cross‐Sectional Study

Neuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
In chronic schizophrenia, serum adiponectin levels were positively associated with antipsychotic dosage, particularly with multi‐acting receptor‐targeted antipsychotics and were influenced by gender and hospitalization period. These findings highlight gender‐specific metabolic regulation and the importance of monitoring adipokines during long‐term ...
Yasuhiro Ohno, Kiyomi Saito, Keita Hanabusa, Ayaka Nakai, Tomoko Nagai, Noriko Hida, Kenji Sanada   +6 more
wiley   +1 more source

Clozapine for treatment‐resistant schizophrenia with epilepsy: A case report

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 2, June 2026.
Clozapine (CLOZ) is often avoided in treatment‐resistant schizophrenia with comorbid epilepsy due to seizure risks. We report a successful case managed through a cautious CLOZ titration guided by multimodal monitoring, including clinical scales and blood tests such as C‐reactive protein (CRP), CLOZ levels, and anti‐seizure medication (ASM) levels ...
Toru Horinouchi, Mayusa Mito, Toshiyuki Ishikawa, Yuichi Nakamura, Shuhei Ishikawa, Naoki Hashimoto   +5 more
wiley   +1 more source

Olanzapine: Are Extrapyramidal Symptoms as Rare as We Think? – A Case Series

Archives of Medicine and Health Sciences
Olanzapine, a second-generation antipsychotic has proven to be very efficacious with a low probability of extrapyramidal symptoms (EPS). Here, we wish to report a series of cases where EPS is occurring as a rare side effect due to olanzapine.
Akansha Bhardwaj, Bushra Zahoor, Kirti Yadav, Gunjan Chadha   +3 more
doaj   +1 more source