Results 91 to 100 of about 28,600 (213)
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen +3 more
wiley +1 more source
Understanding excessive sleep in people with psychotic disorders
Abstract Background There has been increasing attention to sleep disturbances such as insomnia in psychosis, due to its impact on symptoms, well‐being, and recovery. However, excessive sleep and extended sleep duration are common in psychosis (partly linked to sedating antipsychotic medication) and have been relatively neglected, despite plausible ...
Kate Robbins +2 more
wiley +1 more source
ABSTRACT Eccrine squamous syringometaplasia (ESS) is an uncommon reactive alteration of eccrine ducts, most often reported in oncologic and transplant settings, where it may clinically mimic acute cutaneous graft‐versus‐host disease (GVHD). We describe a 3‐year‐old boy with chronic granulomatous disease who developed a diffuse erythematous eruption 6 ...
Benedetta Galli +5 more
wiley +1 more source
Emergency Department Triage Nurses' Scope of Practice: An Observational Study
ABSTRACT Aim To explore emergency department triage nurses' scope of practice and activities related to their triage role and management of patients located in emergency department waiting areas. Design Exploratory, descriptive, observational study using naturalistic decision making.
Julie Considine +8 more
wiley +1 more source
Aims While pregnancy‐related changes in phase I enzyme activity are well‐documented, less is known about the impact on phase II enzymes. This study aimed to test the hypothesis that changes in the pharmacokinetics (PK) of uridine 5′‐diphosphoglucuronosyltransferase (UGT) substrates during pregnancy result from altered enzyme expression or activity ...
William Saffaf +6 more
wiley +1 more source
Rosaria Di Lorenzo1, Alice Brogli21Department of Mental Health, AUSL-MODENA, Presidio Psichiatrico di Diagnosi e Cura 1, NOCSAE, Baggiovara, Modena, Italy; 2School of Specialization in Psychiatry, University of Modena e Reggio Emilia, Modena ...
Rosaria Di Lorenzo, Alice Brogli
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Endogenous melatonin partial metabolic clearance as a potential endogenous marker of CYP1A2 activity
Aims Cytochrome P450 1A2 (CYP1A2) exhibits substantial interindividual variability, necessitating appropriate phenotyping strategies for personalized pharmacotherapy. This study evaluated endogenous melatonin partial metabolic clearance (CLm(MEL)), calculated from urinary 6‐hydroxymelatonin (6‐O‐MEL) excretion and plasma melatonin (MEL) exposure, as a ...
Akitomo Yokokawa +5 more
wiley +1 more source
ARFID Triggered by Dysgeusia: A Case Report on Light Therapy, Nutritional Support, and Mirtazapine
ABSTRACT Here, we describe an older man who developed avoidant‐restrictive food intake after an acute onset of dysgeusia that persisted for nearly two years. After initiating a multifactorial treatment approach that included light therapy, nutritional support, and mirtazapine, both the eating disorder and dysgeusia resolved within months.
Aanika Kashyap +2 more
wiley +1 more source
CYP2C19 Genotype is Associated with Citalopram Treatment Outcomes in a Real‐World Setting
CYP2C19 metabolizes various selective serotonin reuptake inhibitors (SSRIs) and genetic CYP2C19 variants are associated with SSRI tolerability and response. Yet, whether CYP2C19 variability also impacts citalopram response remained unclear. We here evaluated associations between CYP2C19 genotypes and citalopram prescription data of 11,079 patients from
Yoomi Park +2 more
wiley +1 more source

