Results 81 to 90 of about 60,520 (273)

Association between olanzapine concentration and metabolic dysfunction in drug-naive and chronic patients: similarities and differences

open access: yesnpj Schizophrenia, 2022
Second-generation antipsychotics are widely used to treat schizophrenia but their use could induce metabolic dysfunction. To balance efficacy and side effects, various guidelines recommend the use of therapeutic drug monitoring.
Dongyu Kang   +4 more
doaj   +1 more source

Olanzapine [PDF]

open access: yesReactions Weekly, 2021
Brett Yamane   +2 more
openaire   +2 more sources

Population‐Stratified Distributions of Post‐Mortem Blood Drug Concentrations: An Epidemiological Framework for Contextual Interpretation

open access: yesDrug Testing and Analysis, EarlyView.
Post‐mortem blood drug concentrations exhibit substantial overlap between deaths in which a drug was implicated and those in which it was not. Analysis of over 58,000 NPSUM cases demonstrates that demographic stratification does not resolve this uncertainty, reinforcing the need for contextual, evidence‐based interpretation rather than concentration ...
Thikra Algahtani   +6 more
wiley   +1 more source

Therapeutic study of the nausea and vomiting caused by chemotherapy medications by olanzapine to triple antiemetic therapy in Iraqi cancer patients

open access: yesAl-Mustansiriyah Journal of Pharmaceutical Sciences, 2023
Background:Chemotherapy-caused nausea and vomiting is a health problem in cancer patients. Olanzapine is used with serotonin receptor antagonists plus dexamethasone post Neurokinin 1 receptor antagonists as the antiemetic.
Ghufran salah ahmed   +2 more
doaj   +1 more source

Midazolam‐Droperidol, Droperidol, or Olanzapine for Acute Agitation: A Randomized Clinical Trial

open access: yesAnnals of Emergency Medicine, 2017
Study objective: We aim to determine the most efficacious of 3 common medication regimens for the sedation of acutely agitated emergency department (ED) patients.
D. Taylor   +8 more
semanticscholar   +1 more source

Olanzapine for the prevention and treatment of cancer-related nausea and vomiting in adults.

open access: yesCochrane Database of Systematic Reviews, 2017
BACKGROUND Olanzapine as an antiemetic represents a new use of an antipsychotic drug. People with cancer may experience nausea and vomiting whilst receiving chemotherapy or radiotherapy, or whilst in the palliative phase of illness.
A. Sutherland   +6 more
semanticscholar   +1 more source

Falls in Huntington's Disease: A Cross‐Sectional Analysis of Clinical Features and Potential Contributors

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Falls occur across all stages of Huntington's disease (HD) and are associated with poor quality of life and injury. However, there is limited information on falls in HD. Objective The aim was to investigate the clinical features potentially associated with falls in HD. Methods We conducted a cross‐sectional, analytical observational
Arthur Pena Ferreira   +5 more
wiley   +1 more source

Olanzapine-activated AMPK signaling in the dorsal vagal complex is attenuated by histamine H1 receptor agonist in female rats

open access: yes, 2014
Weight gain and its related metabolic disorders are major side-effects associated with second generation antipsychotic drug (SGA) treatment. The dorsal vagal complex (DVC) and AMP-activated protein kinase (AMPK) are implicated in the regulation of food ...
Meng He (20118228)   +4 more
core   +1 more source

Long-term functional improvements in the 2-year treatment of schizophrenia outpatients with olanzapine long-acting injection

open access: yesNeuropsychiatric Disease and Treatment, 2014
Haya Ascher-Svanum,1 Diego Novick,2,3 Josep Maria Haro,4 Jordan Bertsch,4 David McDonnell,1 Holland Detke11Eli Lilly and Company, Indianapolis, IN, USA; 2Eli Lilly and Company, Windlesham, Surrey, UK; 3Departament de Psiquiatria, Universitat Autonoma de ...
Ascher-Svanum H   +5 more
doaj  

Early Lipid Metabolic Effects of the Anti-Psychotic Drug Olanzapine on Weight Gain and the Associated Gene Expression

open access: yesNeuropsychiatric Disease and Treatment, 2022
Chien-Chih Chen,1,2 Toshiaki Nakano,3,4 Li-Wen Hsu,3,4 Chia Yi Chu,1 Kuang-Tzu Huang4,5 1Department of Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; 2School of Medicine, Chang Gung ...
Chen CC   +4 more
doaj  

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