Results 111 to 120 of about 665 (160)

Rotation Conformational Effects of Selected Cytotoxic Cardiac Glycosides on Their Interactions with Na⁺/K⁺-ATPase. [PDF]

Molecules
Ren Y, Yang P, Gallucci JC, Wang C, Cheng X, Wu S, Kinghorn AD.   +6 more
europepmc   +1 more source

[Determination of 13 prohibited alkaloids in essential oil-based cosmetics by ultra performance liquid chromatography-tandem mass spectrometry combining QuEChERS purification]. [PDF]

Se Pu
Liu Z, Wang YM, Pan JB, Zong LL, Song YH, Sun XJ, Chen HY.   +6 more
europepmc   +1 more source

Feud, Flower, and Fatal Electrocardiograms. [PDF]

Cureus
Veeraraghavan S, Kidambi BR, Reddy SK, Vijay S, Munisingh A, Ponnangati V.   +5 more
europepmc   +1 more source

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Synthesis of oleandrin derivatives and their cytotoxic activity

Steroids, 2020
A series of oleandrin-4'-yl ester derivatives were designed, synthesized, and evaluated for their proliferation inhibition activities against tumor cell lines. Cytotoxicity data revealed that the C4' moiety had an important influence on cytotoxic activity. Several compounds that we designed and synthesized exhibit significant in vitro antiproliferative
Yanzhi, Zhang, Xubing, Chen, Yang, Zhou, Jinjun, Hou, Huali, Long, Zijia, Zhang, Min, Lei, Wanying, Wu   +7 more
openaire   +2 more sources

Enhancement of radiotherapy by oleandrin is a caspase-3 dependent process

Cancer Letters, 2002
Cardiac glycosides such as digitoxin and ouabain have previously been shown to be selectively cytotoxic to tumor as opposed to normal cells. Moreover, this class of agents has also been shown to act as potent radiosensitizers. In the present study we explored the relative radiosensitization potential of oleandrin, a cardiac glycoside contained within ...
Luka Milas, Uma Raju, Robert A Newman
exaly   +3 more sources

A fatal case of oleandrin poisoning

Forensic Science International, 2008
The study presents a case of fatal poisoning with oleander leaves in an adult diabetic male. After repeated vomiting, and gastrointestinal distress the patient was admitted at the hospital with cardiac symptoms 1h after the ingestion. Urine samples were assayed immunochemically and by GC-MS for drugs of abuse and for general toxicological screen. Blood
Ibrahim A, Wasfi, Omar, Zorob, Nawal A, Al katheeri, Anwar M, Al Awadhi   +3 more
exaly   +3 more sources

Antitumor effects of oleandrin in different types of cancers: Systematic review

Toxicon, 2022
Oleandrin, a cardiac glycoside isolated from the leaves of Nerium oleander, has known effects on the heart. Evidence from recent studies have highlighted its potential for anticancer properties. Therefore, we aimed to investigate the effects of oleandrin on cancer cell proliferation, viability and apoptosis in vitro and in vivo.
Cristiane Raquel Dias, Francischini, Carolina Rodrigues, Mendonça, Kênia Alves, Barcelos, Marco Augusto Machado, Silva, Ana Flávia Machado, Botelho   +4 more
openaire   +2 more sources

Effects of Oleandrin on Cardiovascular Hemodynamics in the Dog

American Journal of Veterinary Research, 1979
SUMMARY The cardiovascular effects of oleandrin, a cardiac glycoside isolated from Nerium oleander Linnaeus, were studied in anesthetized dogs with intact circulation. Oleandrin was given as a single iv injection at dosages of 0.01 (group I), 0.02 (group II), and 0.05 mg (group III)/kg of body weight, and measurements were made 0 (base line), 15, 30 ...
S I, Deavers, J P, Rosborough, H E, Hoff, J D, McCrady   +3 more
openaire   +2 more sources