Results 131 to 140 of about 873 (179)

Overcoming immunotherapy resistance in breast cancer: a novel strategy by targeting the integrated stress response. [PDF]

open access: yesFront Cell Dev Biol
Yue J   +10 more
europepmc   +1 more source
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A fatal case of oleandrin poisoning

Forensic Science International, 2008
The study presents a case of fatal poisoning with oleander leaves in an adult diabetic male. After repeated vomiting, and gastrointestinal distress the patient was admitted at the hospital with cardiac symptoms 1h after the ingestion. Urine samples were assayed immunochemically and by GC-MS for drugs of abuse and for general toxicological screen. Blood
Ibrahim A, Wasfi   +3 more
exaly   +3 more sources

Enhancement of radiotherapy by oleandrin is a caspase-3 dependent process

Cancer Letters, 2002
Cardiac glycosides such as digitoxin and ouabain have previously been shown to be selectively cytotoxic to tumor as opposed to normal cells. Moreover, this class of agents has also been shown to act as potent radiosensitizers. In the present study we explored the relative radiosensitization potential of oleandrin, a cardiac glycoside contained within ...
Uma Raju, Luka Milas
exaly   +3 more sources

Glycoside oleandrin downregulates toll-like receptor pathway genes and associated miRNAs in human melanoma cells [PDF]

open access: yesGene, 2022
Melanoma accounts for the majority of skin cancer-related deaths. Nerium oleander is a plant known to be toxic and consumed due to the cardiac glycosides it contains. Oleandrin is a cardiac glycoside obtained from of N. oleander.
Fatma Seçer Çelik   +2 more
exaly   +2 more sources

Regulation of Intrinsic and Extrinsic Apoptotic Pathways in Osteosarcoma Cells Following Oleandrin Treatment

open access: yesInternational Journal of Molecular Sciences, 2016
Our previous study has reported the anti-tumor effect of oleandrin on osteosarcoma (OS) cells. In the current study, we mainly explored its potential regulation on intrinsic and extrinsic apoptotic pathway in OS cells.
Xiaoguang Liu   +2 more
exaly   +2 more sources

Oleandrin: A bioactive phytochemical and potential cancer killer via multiple cellular signaling pathways [PDF]

open access: yesFood and Chemical Toxicology, 2020
Nerium oleander, a member of family Apocynaceae, is commonly known as Kaner in various countries of Asia and Mediterranean region. This plant has been renowned to possess significant therapeutic potential due to its various bioactive compounds which have
Ammara Riaz   +2 more
exaly   +2 more sources

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