Results 11 to 20 of about 20,571 (205)

Oleanolic Acid: Extraction, Characterization and Biological Activity [PDF]

Nutrients, 2022
Oleanolic acid, a pentacyclic triterpenoid ubiquitously present in the plant kingdom, is receiving outstanding attention from the scientific community due to its biological activity against multiple diseases. Oleanolic acid is endowed with a wide range of biological activities with therapeutic potential by means of complex and multifactorial mechanisms.
José M. Castellano, Sara Ramos-Romero, Javier S. Perona   +2 more
openaire   +3 more sources

Application and Development of Natural Plant Metabolite Oleanolic Acid in the Nano Era

Agriculture, 2022
Like other pentacyclic triterpenoids, oleanolic acid, a natural plant metabolite prevalent in plant peels, stems, and leaves, is regarded as a possible drug candidate.
Kun Wang, Qinyue Lu, Xiang Cao, Yuhao Wang, Yanni Wu, Zhi Chen, Zhangping Yang   +6 more
doaj   +1 more source

Pomace Olive Oil Concentrated in Triterpenic Acids Restores Vascular Function, Glucose Tolerance and Obesity Progression in Mice [PDF]

, 2020
Pomace olive oil, an olive oil sub-product, is a promising source of bioactive triterpenoids such as oleanolic acid and maslinic acid. Considering the vascular actions of pomace olive oil and the potential effects of the isolated oleanolic acid on ...
Claro Cala, Carmen María, Herrera González, María Dolores, Miñano Sánchez, Francisco Javier, Pérez Montero , Marta, Quintela, José Carlos, Rodríguez Rodríguez , Rosalía, Álvarez de Sotomayor Paz, María   +6 more
core   +1 more source

Economically viable isolation and characterization of oleanolic acid from Eugenia caryophyllus (Spreng.)

Kuwait Journal of Science, 2020
Oleanolic acid, an interesting molecule found widespread throughout the plant kingdom with promising pharmacological activities. However, the utilization of oleanolic acid in the modern therapy is quite difficult due to lack of proper isolation method ...
Nilesh Bhimrao Banarase, Chanchal Deep Kaur   +1 more
doaj   +1 more source

A seed-specific regulator of triterpene saponin biosynthesis in Medicago truncatula [PDF]

, 2020
Plants produce a vast array of defense compounds to protect themselves from pathogen attack or herbivore predation. Saponins are a specific class of defense compounds comprising bioactive glycosides with a steroidal or triterpenoid aglycone backbone. The
Arendt, Philipp, Bicalho, Keylla, Buitink, Julia, Calegario, Gabriela, Ceulemans, Evi, Goossens, Alain, Gryffroy, Lore, Lacchini, Elia, Mertens, Jan, Pollier, Jacob, Ribeiro, Bianca, Vanden Bossche, Robin   +11 more
core   +2 more sources

Oleanolic acid 3-acetate, a minor element of ginsenosides, induces apoptotic cell death in ovarian carcinoma and endometrial carcinoma cells via the involvement of a reactive oxygen species–independent mitochondrial pathway

Journal of Ginseng Research, 2020
Objectives: Oleanolic acid, a minor element of ginsenosides, and its derivatives have been shown to have cytotoxicity against some tumor cells. The impact of cytotoxic effect of oleanolic acid 3-acetate on ovarian cancer SKOV3 cells and endometrial ...
Hantae Jo, Jeong-Hyun Oh, Dong-Wook Park, Changho Lee, Churl K. Min   +4 more
doaj   +1 more source

Development of Polymeric Micelles of Oleanolic Acid and Evaluation of Their Clinical Efficacy

Nanoscale Research Letters, 2020
Oleanolic acid has been used only as a subsidiary agent in cosmetic products. The aim of the study is to show the effect of oleanolic acid as an active ingredient for the alleviation of wrinkles in humans and to develop a polymeric micelle formulation ...
Joo Young An, Hee Seon Yang, Na Rae Park, Tae-sung Koo, Bungchul Shin, Eun Hee Lee, Sun Hang Cho   +6 more
doaj   +1 more source

Anti-dengue activity of super critical extract and isolated oleanolic acid of Leucas cephalotes using in vitro and in silico approach

BMC Complementary Medicine and Therapies, 2021
Backgrounds Leucas cephalotes is a common ethnomedicinal plant widely used by traditional healers for the treatment of Malaria and other types of fever. Oleanolic acid and its derivatives have been reported for various types of pharmacological activities,
Sulochana Kaushik, Lalit Dar, Samander Kaushik, Jaya Parkash Yadav   +3 more
doaj   +1 more source

High-yield bioactive triterpenoid production by heterologous expression in Nicotiana benthamiana using the Tsukuba system

Frontiers in Plant Science, 2022
Oleanolic acid is a pentacyclic triterpenoid found in numerous plant species and is a precursor to several bioactive triterpenoids with commercial potential.
Jutapat Romsuk, Shuhei Yasumoto, Shuhei Yasumoto, Ery Odette Fukushima, Ery Odette Fukushima, Kenji Miura, Toshiya Muranaka, Toshiya Muranaka, Hikaru Seki, Hikaru Seki   +9 more
doaj   +1 more source

Oleanolic acid from black raisins, Vitis vinifera with antioxidant and antiproliferative potentials on HCT 116 colon cancer cell line

Brazilian Journal of Pharmaceutical Sciences, 2020
Vitis vinifera (black raisin) is commonly used in traditional medicine for the treatment of various ailments. In the present study, anti-oxidative and anti-cancer efficacy of oleanolic acid from ethyl acetate fraction of black raisins was evaluated and ...
Kandasamy Sasikumar, Vinay Dubey, Asit Ranjan Ghosh   +2 more
doaj   +1 more source