Results 61 to 70 of about 20,571 (205)

Integrating mass spectrometry and systems biology for the modernization of natural medicines: From deciphering chemical complexity to holistic efficacy assessment

open access: yesVIEW, EarlyView.
This review explores how mass spectrometry is transforming research in natural medicines, with Traditional Chinese medicine (TCM) as a primary exemplar. It details the application of advanced mass spectrometry in chemical analysis, the development of comprehensive quality control methods, and systematic research on the targeted mechanisms of single ...
Yudian Xu   +7 more
wiley   +1 more source

Self-microemulsifying drug delivery system for improved oral bioavailability of oleanolic acid: design and evaluation

open access: yesInternational Journal of Nanomedicine, 2013
Rui Yang,1 Xin Huang,1 Jinfeng Dou,2 Guangxi Zhai,2 Lequn Su1 1Pharmacy Department, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, People's Republic of China; 2Department of Pharmaceutics, College of Pharmacy, Shandong ...
Yang R, Huang X, Dou J, Zhai G, Su L
doaj  

Bioinformatics exploration of olive oil: molecular targets and properties of major bioactive constituents

open access: yesOilseeds and fats, crops and lipids, 2021
Olive oil possesses medicinal properties which include antimicrobial, antioxidant and anti-inflammatory, anti-diabetes, and anti-cardiovascular diseases.
Fatoki Toluwase Hezekiah   +2 more
doaj   +1 more source

Ursolic and oleanolic acids as antimicrobial and immunomodulatory compounds for tuberculosis treatment [PDF]

open access: yes, 2013
BACKGROUND: New alternatives for the treatment of Tuberculosis (TB) are urgently needed and medicinal plants represent a potential option. Chamaedora tepejilote and Lantana hispida are medicinal plants from Mexico and their hexanic extracts have shown ...
Adelina Jiménez-Arellanes   +9 more
core   +1 more source

Recent advances in nanoparticle formulation of oleanolic acid [PDF]

open access: yesChinese Medicine, 2011
Abstract Oleanolic acid (OA) is a natural triterpenoid possessing anti-inflammatory, antitumor, antiviral, hepatoprotective and antihyperlipidemic effects. Research on the pharmacological activities and clinical applications of OA has made significant progress in the past decade, particularly in the areas such as isolation and purification ...
Wang Shengpeng   +4 more
openaire   +3 more sources

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

open access: yesJournal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed   +6 more
wiley   +1 more source

Inhibitory activity of Kaki calyx extracts and their triterpene compounds on recombinant hepatitis C virus NS3/4A protease [PDF]

open access: yes, 2018
柿蔕のヘキサン、メタノール、50 % アセトン抽出物の、組み替えhepatitis C virus (HCV)の NS3/4A 蛋白質分解酵素に対する阻害活性を検討した。50 % アセトン抽出物が最も阻害活性が強く、この抽出物をSephadex LH20カラムで分画を行なった。得た各画分のうち阻害活性の強かった70 %メタノール画分を、さらにシリカゲルカラム/薄層クロマトグラフィーで分画し、トリテルペンのベルリン酸、オレアノール酸、ウルソール酸を分離した。これらのトリテルペンはpolycyclic ...
Isao OHTSUKA   +14 more
core   +1 more source

Analysis of BpbHLH Gene Family Responsive to MeJA Signalling in Betula platyphylla Suk. and Functional Mechanisms of BpbHLH42/44 in Genetic Improvement and Triterpenoid Biosynthesis

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT The basic helix–loop–helix (bHLH) transcription factor family regulates plant secondary metabolism, development and stress responses. Although triterpenoids such as betulinic acid (BA), betulin (BT) and oleanolic acid (OA) from Betula platyphylla Suk.
Ying Li   +9 more
wiley   +1 more source

Spray dried oleanolic acid powder for pulmonary delivery [PDF]

open access: yes, 2013
Poster Presentation: no. 13PS51The abstract of the poster presentation is located at http://inhalationasia.org/index.php/poster-presentations/176-13ps51-shuangning-chenIntroduction: Oleanolic acid (OA), well known for its hepatoprotective effect, has ...
Chen, S, Kwok, PCL, Tong, HHY
core  

Saikosaponin A Inhibits Migration/Invasion and Triggers Cell‐Cycle Arrest and Autophagy‐Induced Cell Death in HCT116 Cells and In Vivo

open access: yesFood Frontiers, Volume 7, Issue 3, May 2026.
Saikosaponin A from Radix Bupleuri inhibited colorectal cancer HCT116 cells with low toxicity. SSA induced S/G2‐M cell cycle arrest and triggered autophagy via mTOR inhibition. SSA suppressed metastasis by blocking PI3K/AKT signaling pathway. SSA significantly reduced tumor growth without apparent toxicity.
Xiu‐Xiu Zhang   +7 more
wiley   +1 more source

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