Results 101 to 110 of about 347,140 (343)

Immature olfactory sensory neurons provide behaviourally relevant sensory input to the olfactory bulb

open access: yesNature Communications, 2022
New olfactory sensory neurons (OSNs) wire into highly organized olfactory bulb circuits throughout life. Here, the authors show that immature OSNs provide behaviourally relevant sensory input to olfactory bulb neurons that is functionally distinct from ...
Jane S. Huang   +9 more
doaj   +1 more source

Glomerular microcircuits in the olfactory bulb [PDF]

open access: yesNeural Networks, 2009
Microcircuits in the olfactory bulb have long received particular attention from both experimentalists and theoreticians, due in part to an abundance of dendrodendritic interactions and other specialized modifications to the canonical cortical circuit architecture.
Christiane Linster, Thomas A. Cleland
openaire   +2 more sources

A Novel Bioactive Component, Efoba, From Aged Garlic Targets CTSC to Suppress NET‐Driven Neuroinflammation and Ameliorate Secondary Brain Injury After Intracerebral Hemorrhage

open access: yesAdvanced Science, EarlyView.
Efoba, a novel bioactive component derived from aged garlic, confers neuroprotection against intracerebral hemorrhage. It acts on microglia to suppress CTSC release, inhibits NET‐mediated neural injury, and blocks pathological microglia‐neutrophil crosstalk. This study provides a highly promising lead compound for hemorrhagic‐stroke therapy.
Junjun Meng   +7 more
wiley   +1 more source

Paced-mating increases the number of adult new born cells in the internal cellular (granular) layer of the accessory olfactory bulb. [PDF]

open access: yesPLoS ONE, 2011
The continuous production and addition of new neurons during life in the olfactory bulb is well accepted and has been extensively studied in rodents. This process could allow the animals to adapt to a changing environment.
Rebeca Corona   +2 more
doaj   +1 more source

Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics

open access: yesAdvanced Intelligent Discovery, EarlyView.
Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong   +5 more
wiley   +1 more source

Zebrafish Astroglial Morphology in the Olfactory Bulb Is Altered With Repetitive Peripheral Damage

open access: yesFrontiers in Neuroanatomy, 2020
Zebrafish do not possess the typical astrocytes that are found in mammalian systems. In some brain areas, this teleost has radial glia that appears to perform astrocyte-like functions, but these cells have not been described in the zebrafish olfactory ...
Jackson Scheib, Christine Byrd-Jacobs
doaj   +1 more source

Independent control of gamma and theta activity by distinct interneuron networks in the olfactory bulb

open access: yesNature Neuroscience, 2014
Circuits in the brain possess the ability to orchestrate activities on different timescales, but the manner in which distinct circuits interact to sculpt diverse rhythms remains unresolved. The olfactory bulb is a classic example of a place in which slow
Izumi Fukunaga   +4 more
semanticscholar   +1 more source

Massive transient damage of the olfactory epithelium associated with infection of sustentacular cells by SARS-CoV-2 in golden Syrian hamsters

open access: yesbioRxiv, 2020
Anosmia is one of the most prevalent symptoms of SARS-CoV-2 infection during the COVID-19 pandemic. However, the cellular mechanism behind the sudden loss of smell has not yet been investigated.
Bertrand Bryche   +15 more
semanticscholar   +1 more source

Model parameters of the olfactory bulb neurons.

open access: yes, 2014
Model parameters of the olfactory bulb neurons.
Agustin Gutierrez-Galvez (319070)   +4 more
core   +1 more source

Biallelic PAX6 Variants in an Adult With Severe Microphthalmia and Preserved Intellectual Function

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT PAX6 encodes a dosage‐sensitive transcription factor that is essential for eye development. Heterozygous PAX6 disease is well characterized, but biallelic disease is extremely rare and has been associated with anophthalmia, severe brain malformations, and perinatal lethality.
Karl De Geer   +4 more
wiley   +1 more source

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