Results 121 to 130 of about 52,860 (309)

Exocrine Gland Dysfunction in Parkinson's Disease: Pathophysiology, Clinical Manifestations, and Therapeutic Perspectives—A Narrative Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz, Marina Farah, Laura Silveira‐Moriyama   +2 more
wiley   +1 more source

Amorphological and histological study of the olfactory organ in Parasilurus triostegus (Heckel)

Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017
The morphological description and histological structure of the olfactory     organ     of    Parasilurus     triostegus     (Heckel)     have    been investigated.
M. Q. Najeb, H.A.M. Dauod, M.A. Gali
doaj  

Co‐ and Multi‐Pathologies in Parkinson's Disease: An International Parkinson and Movement Disorder Society Scientific Issues Committee Review

Movement Disorders, EarlyView.
Abstract Parkinson's disease (PD) has been historically defined as a disease of striatal dopamine deficiency secondary to degeneration of dopaminergic neurons in the substantia nigra pars compacta, related to the presence of Lewy bodies and Lewy neurites.
Michele Matarazzo, Per Borghammer, Inas Elsayed, Jennifer G. Goldman, Yue Huang, Katja Lohmann, Per Svenningsson, Lorraine V. Kalia, Daniela Berg, Jeffrey H. Kordower, the MDS Scientific Issues Committee   +10 more
wiley   +1 more source

Reduced olfactory bulb volume accompanies olfactory dysfunction after mild SARS-CoV-2 infection

Scientific Reports
Despite its high prevalence, the determinants of smelling impairment in COVID-19 remain not fully understood. In this work, we aimed to examine the association between olfactory bulb volume and the clinical trajectory of COVID-19-related smelling ...
Marvin Petersen, Benjamin Becker, Maximilian Schell, Carola Mayer, Felix L. Naegele, Elina Petersen, Raphael Twerenbold, Götz Thomalla, Bastian Cheng, Christian Betz, Anna S. Hoffmann   +10 more
doaj   +1 more source

The Olfactory Nervous System Of Terrestrial And Aquatic Vertebrates

, 2011
Animals in their natural milieu are surrounded by odors. These odors are rich source of information, and are perceived by sophisticated olfactory systems, that have evolved over time.
Ashiq Hussain
core  

Olfactory bulb interneurons releasing NO exhibit the Reelin receptor ApoEr2 and part of those targeted by NO express Reelin

, 2008
Nitric oxide (NO) and Reelin both modulate neuronal plasticity in developing and mature synaptic networks. We recently showed a loss of neuronal nitric oxide synthase (nNOS) protein in the olfactory bulb of reeler mutants and advanced the hypothesis that
Herrmann, Gudrun, Mishev, Georgi, Scotti, Alessandra L   +2 more
core   +1 more source

Heterogenous Neuropathology in a Pedigree with RAB39B‐Related Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background In 2015, we reported a family with Parkinson's disease resulting from the RAB39B p.G192R (c.574G>A) variant. Since then, two affected brothers from the family have undergone autopsy. Objectives To characterize neuropathological findings, assess intracellular distribution of RAB39B protein, and examine the effect of p.G192R on α ...
Caitlin Latimer, Oswaldo Lorenzo‐Betancor, Dong‐Hui Chen, Kimmy Su, Marika Bogdani, Anna J. Park, Minsuh Kim, Joshua Weiss, Malia Callier, Ella H. Chiu, Sarah Fish, Jennifer L. Witt, Wendy H. Raskind, Marie Y. Davis, C. Dirk Keene, Cyrus P. Zabetian   +15 more
wiley   +1 more source

Olfactory bulb activity images.

, 2013
The olfactory bulb activity measured gives a pattern obtained using uptake of [14C]-2DG when exposed to 2-ethylfuran (up, left) and exposed to 1,7-octadiene (bottom, left). The corresponding binary map of the olfactory bulb activity for 2-ethylfuran (top,
Agustin Gutierrez-Galvez (319070), Santiago Marco (319071), Jordi Fonollosa (319067)   +2 more
core   +1 more source

Flavonoids in Nasal Therapeutics: Biological Activities, Delivery Challenges, and Formulation Strategies–A Systematic Review

Phytotherapy Research, EarlyView.
Overview of the therapeutic potential of flavonoids in nasal delivery systems, highlighting their benefits to the human nasal cavity, and applications in the treatment of respiratory and brain‐related diseases. ABSTRACT Flavonoids represent a significant group of secondary metabolites.
Jeniffer Viviana Ramirez Hernández, Sara Elis Bianchi, Flávia Nathiely Silveira Fachel, Elizandra Braganhol, Sheila Porto de Matos, Valquíria Linck Bassani   +5 more
wiley   +1 more source

As alterações gastrointestinais e olfatórias precedem os sinais motores no modelo experimental da doença de Parkinson induzido pela rotenona [PDF]

, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Farmacologia, Florianópolis, 2013Existem hipóteses que o processo patológico da Doença de Parkinson inicia-se no Sistema Nervoso ...
Morais, Lívia Hecke
core