Results 141 to 150 of about 247,698 (320)

Delivery strategies of messenger RNA therapeutics for brain disorders

Bulletin of the Korean Chemical Society, EarlyView.
Thus, mRNA therapeutics offer a powerful new avenue for the treatment of brain diseases. This review examines strategies to bypass biological barriers, particularly the blood–brain barrier, and explores emerging delivery systems, such as direct intracerebral injection, intracerebroventricular injection, systemic delivery (including intravenous ...
Kounghwa Youn, Sunmin Oh, Hyunchae Gil, Yongseok Choi, Gyochang Keum, Eun‐Kyoung Bang   +5 more
wiley   +1 more source

The Wire Is Not the Territory: Understanding Representational Drift in Olfaction With Dynamical Systems Theory

Topics in Cognitive Science, EarlyView., 2023
Abstract Representational drift is a phenomenon of increasing interest in the cognitive and neural sciences. While investigations are ongoing for other sensory cortices, recent research has demonstrated the pervasiveness in which it occurs in the piriform cortex for olfaction.
Ann‐Sophie Barwich, Gabriel J. Severino   +1 more
wiley   +1 more source

Reduced olfactory bulb volume accompanies olfactory dysfunction after mild SARS-CoV-2 infection

Scientific Reports
Despite its high prevalence, the determinants of smelling impairment in COVID-19 remain not fully understood. In this work, we aimed to examine the association between olfactory bulb volume and the clinical trajectory of COVID-19-related smelling ...
Marvin Petersen, Benjamin Becker, Maximilian Schell, Carola Mayer, Felix L. Naegele, Elina Petersen, Raphael Twerenbold, Götz Thomalla, Bastian Cheng, Christian Betz, Anna S. Hoffmann   +10 more
doaj   +1 more source

Effects of Ambient and Display Lighting Color on Risk‐Taking Behavior, Perceived Emotional States, and Visual Quality of Indoor Environment

Color Research &Application, EarlyView.
In a digital risk‐taking test, participants inflated a balloon to increase earned points at the risk of popping under different display and ambient lighting conditions. ABSTRACT Lighting from architectural fixtures and screens can have impacts beyond visual perception, such as occupants' cognitive functions and emotional states. Despite the ubiquity of
Naser Shehab, Dorukalp Durmus
wiley   +1 more source

Modeling the Olfactory Bulb - Coupled Nonlinear Oscillators [PDF]

, 1989
The olfactory bulb of mammals aids in the discrimination of odors. A mathematical model based on the bulbar anatomy and electrophysiology is described.
Hopfield, J. J., Li, Zhaoping
core  

Dynamic expression of lamin B1 during adult neurogenesis in the vertebrate brain

Developmental Dynamics, EarlyView.
Abstract Background In mammals, specific brain regions such as the dentate gyrus (DG) of the hippocampus and the subventricular zone (SVZ) of the lateral ventricles harbor adult neural stem/progenitor cells (ANSPCs) that give rise to new neurons and contribute to structural and functional brain plasticity.
Diana Zhilina, Lizbeth A. Bolaños Castro, Juan Sebastian Eguiguren, Sara Zocher, Anne Karasinsky, Dimitri Widmer, Alexandre Espinós, Victor Borrell, Michael Brand, Kyoko Miura, Oliver Zierau, Maximina H. Yun, Tomohisa Toda   +12 more
wiley   +1 more source

Amorphological and histological study of the olfactory organ in Parasilurus triostegus (Heckel)

Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017
The morphological description and histological structure of the olfactory     organ     of    Parasilurus     triostegus     (Heckel)     have    been investigated.
M. Q. Najeb, H.A.M. Dauod, M.A. Gali
doaj  

A comprehensive embryonic staging series of the turtle Trachemys scripta

Developmental Dynamics, EarlyView.
Abstract Background Turtles hold a unique place in vertebrate evolutionary history, making them critical assets in embryology research. Yet, they remain understudied as potential model organisms in the field. Here, to support experimental manipulations with turtle embryos, we have created a complete normal table of development for comprehensive ...
Christina M. Noravian, Perla G. Rand, Amira Mahomed, Annie Rickard, Oscar D. Juvera, Maria Elena de Bellard, Max Ezin   +6 more
wiley   +1 more source

Geranium Essential Oil Use for Human Health: A Systematic Review of Clinical Evidence

Flavour and Fragrance Journal, EarlyView.
Geranium essential oil (Pelargonium graveolens) demonstrates efficacy in alleviating anxiety, pain and dermatological conditions, supporting its use as a safe, low‐cost complementary therapy. However, further controlled studies are needed to standardise protocols and confirm its benefits.
Amanda Karina Santos Vieira, Luiza Paes Barbosa, Juliana Rizzo Gnatta   +2 more
wiley   +1 more source

Prolactin Receptor Deficiency Promotes Hypomyelination in White Matter Tracts During Postnatal Central Nervous System Maturation in Mice

Glia, EarlyView.
Prolactin action is essential for proper myelination of white matter tracts during neonatal and prepubertal stages in mice. Lack of prolactin receptor (Prlr−/−) signaling leads to hypomyelination and impaired locomotor function. ABSTRACT A large wave of myelination in the central nervous system (CNS) of mammals occurs during postnatal development ...
Ana L. Ocampo‐Ruiz, José L. Dena‐Beltrán, Marco A. Dimas‐Rufino, Ximena Castillo, Dina I. Vazquez‐Carrillo, Andrea Silos‐Guajardo, Xarubet Ruiz‐Herrera, Edith Garay, Gonzalo Martínez de la Escalera, Carmen Clapp, Rogelio O. Arellano, Abraham J. Cisneros‐Mejorado, Yazmín Macotela   +12 more
wiley   +1 more source