Results 181 to 190 of about 46,881 (221)
Overview of the regulation of intrinsic and extrinsic signals during neurodevelopment. Intrinsic genetic signals from NSCs, in conjunction with cues from microglia and blood vessels, collaboratively regulate the proliferation of NSCs, their fate determination, synaptogenesis, synaptic pruning, neuronal survival, and death, as well as communication ...
Yanyan Wang+4 more
wiley +1 more source
Brain Insulin Receptor Causes Activity-Dependent Current Suppression in the Olfactory Bulb Through Multiple Phosphorylation of Kv1.3 [PDF]
Debra Ann Fadool+3 more
openalex +1 more source
ABSTRACT Background Olfactory neuroblastoma (ONB) is a rare sinonasal malignancy primarily treated with surgery. For tumors arising from the olfactory area, traditional treatment involves transcribriform resection of the anterior cranial fossa. Surgery can be performed with unilateral or bilateral resection depending on extent of involvement; however ...
Arash Abiri+35 more
wiley +1 more source
Isoproterenol Increases CREB Phosphorylation and Olfactory Nerve–Evoked Potentials in Normal and 5-HT-Depleted Olfactory Bulbs in Rat Pups Only at Doses That Produce Odor Preference Learning [PDF]
Qi Yuan+4 more
openalex +1 more source
Alpha‐synuclein co‐pathology in Down syndrome‐associated Alzheimer's disease
Abstract INTRODUCTION Alpha‐synuclein (αSyn) seed amplification assay (SAA) enables in vivo study of αSyn but remains underexplored in Down syndrome‐associated Alzheimer's disease (DSAD). METHODS We analyzed αSyn‐SAA in cerebrospinal fluid (CSF) from 270 adults with Down syndrome, from the Down Alzheimer Barcelona Neuroimaging Initiative and from the ...
Alexander Maximilian Bernhardt+29 more
wiley +1 more source
Abstract Lewy body‐involving diseases (LBD) are commonly associated with Parkinson's disease (PD) featuring voluntary movement inhibition, due to dopaminergic neuron dysfunction in the substantia nigra. PD is clinically tracked through Lewy bodies (LB), composed of insoluble α‐synuclein aggregates sequestered with organelles, particularly inside ...
Victor Z. Lau+4 more
wiley +1 more source
Viral Etiologies and Histopathological Features of Olfactory Dysfunction: A Systematic Review
ABSTRACT Background and Aim Olfactory dysfunction associated with viral infections, including the recent SARS‐CoV‐2 pandemic, has raised significant clinical interest. Understanding the viral etiologies and histopathological characteristics of permanent olfactory dysfunction is essential for optimizing diagnostic and therapeutic strategies.
Kimia Motlagh Asghari+5 more
wiley +1 more source
Sensing Dog Brain Reactions to Smell by AI Speckle Pattern Analysis
The setup of our experiment is shown on Labrador, Johny, a canine participant of our research. The schematic of the setup features: green laser, digital camera, source of smell, and computer. Regions of the brain that were tested are highlighted. Note that the hippocampus and amygdala are on both sides of the dog's brain.
Ilana Propp+5 more
wiley +1 more source
ABSTRACT Neuronal extracellular vesicles (microvesicles and exosomes) are emerging secreted vesicular signals that play important roles in the CNS. Currently, little is known about how glutamatergic signalling affects the subcellular localisation of exosome precursor intraluminal vesicles (ILVs), microRNA (miR) packaging into ILVs and in vivo spreading
Marcela Bertolio+9 more
wiley +1 more source