Results 121 to 130 of about 116,665 (335)
Circuit dynamics of the olfactory pathway during olfactory learning
Frontiers in Neural CircuitsThe olfactory system plays crucial roles in perceiving and interacting with their surroundings. Previous studies have deciphered basic odor perceptions, but how information processing in the olfactory system is associated with learning and memory is ...
Yutian J. Zhang +6 more
doaj +1 more source
Translating novel findings of perceptual-motor codes into the neuro-rehabilitation of movement disorders [PDF]
, 2015 The bidirectional flow of perceptual and motor information has recently proven useful as rehabilitative tool for re-building motor memories. We analyzed how the visual-motor approach has been successfully applied in neurorehabilitation, leading to ...
GALLI, GIULIA, PAZZAGLIA, Mariella
core +2 more sources
Advanced Science, EarlyView.Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley +1 more source
fMRI Evidence for Modality-Specific Processing of Conceptual Knowledge on Six Modalities [PDF]
, 2003 Traditional theories assume that amodal representations, such as feature lists and semantic networks, represent conceptual knowledge about the world. According to this view, the sensory, motor, and introspective states that arise during perception and ...
Barsalou, L.W. +4 more
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Corticofugal projections from the anterior olfactory nucleus target olfactory bulb principal cells [PDF]
, 2011 The anterior olfactory nucleus (AON) is a cortical structure reciprocally connected with the olfactory bulb (OB) and the piriform cortex. Here, using small extracellular and intracellular injections to trace the terminal projections in the OB from ...
Kurt R. Illig
core +2 more sources
Advanced Science, EarlyView.Microglial AXL drives white matter repair after stroke by orchestrating the cleanup of myelin debris. Mechanistically, AXL signals through EGR1 to boost Smpd1 transcription, regulating sphingolipid metabolism and preventing lipid droplet toxicity. Restoring the pathway with ASM therapy mitigates damage, positioning AXL as a key node for therapeutic ...
Junqiu Jia +13 more
wiley +1 more source
Advanced Science, EarlyView.Compared to untargeted therapy, the targeted nanocarrier, Angiopep‐2‐conjugated Lipid Nanoparticle (A‐LNP) loaded with TGN‐020 (TGN), selectively accumulated in stroke‐injured regions. It suppressed local aquaporin‐4 (AQP4) overexpression, thereby alleviating cerebral edema and hypoperfusion while preserving global glymphatic clearance.
Lei Jin +18 more
wiley +1 more source
Volume Conduction Coupling of Whisker-Evoked Cortical LFP in the Mouse Olfactory Bulb
Cell Reports, 2017 Summary: Local field potentials (LFPs) are an important measure of brain activity and have been used to address various mechanistic and behavioral questions.
Ana Parabucki, Ilan Lampl
doaj +1 more source
Fluoxetine: a case history of its discovery and preclinical development [PDF]
, 2014 Introduction: Depression is a multifactorial mood disorder with a high prevalence worldwide. Until now, treatments for depression have focused on the inhibition of monoaminergic reuptake sites, which augment the bioavailability of monoamines in the CNS ...
Bel N +20 more
core +2 more sources
Advanced Science, EarlyView.SAGE is a unified framework for spatial domain identification in spatial transcriptomics that jointly models tissue architecture and gene programs. Topic‐driven gene selection (NMF plus classifier‐based scoring) highlights spatially informative genes, while dual‐view graph embedding fuses local expression and non‐local functional relations.
Yi He +5 more
wiley +1 more source