Results 61 to 70 of about 670,781 (328)

Optogenetic Activation of Dorsal Raphe Serotonin Neurons Rapidly Inhibits Spontaneous But Not Odor-Evoked Activity in Olfactory Cortex

open access: yesJournal of Neuroscience, 2016
Serotonin (5-hydroxytriptamine; 5-HT) is implicated in a variety of brain functions including not only the regulation of mood and control of behavior but also the modulation of perception.
Eran Lottem, M. Lörincz, Z. Mainen
semanticscholar   +1 more source

Acquired olfactory loss alters functional connectivity and morphology

open access: yesScientific Reports, 2021
Removing function from a developed and functional sensory system is known to alter both cerebral morphology and functional connections. To date, a majority of studies assessing sensory-dependent plasticity have focused on effects from either early onset ...
Behzad Iravani   +6 more
doaj   +1 more source

Advancement of PD Is Reflected by White Matter Changes in Olfactory Areas: A Pilot Study

open access: yesMedicina, 2021
Loss of sense of smell is a well-known non-motor symptom of Parkinson’s disease (PD). Here, we present insight into the association between PD advancement and equivalents of smell loss in olfactory-eloquent brain areas, such as the posterior cortex and ...
Thomas Hummel   +5 more
doaj   +1 more source

Large-scale network organization in the avian forebrain: a connectivity matrix and theoretical analysis [PDF]

open access: yes, 2013
Many species of birds, including pigeons, possess demonstrable cognitive capacities, and some are capable of cognitive feats matching those of apes.
Bingman, VP   +4 more
core   +3 more sources

Neural connectivity predicts spreading of alpha-synuclein pathology in fibril-injected mouse models: Involvement of retrograde and anterograde axonal propagation. [PDF]

open access: yes, 2020
In Parkinson's disease, some of the first alpha-synuclein aggregates appear in the olfactory system and the dorsal motor nucleus of the vagus nerve before spreading to connected brain regions.
Brundin, Patrik   +3 more
core   +2 more sources

Differential Serotonergic Modulation of Principal Neurons and Interneurons in the Anterior Piriform Cortex

open access: yesFrontiers in Neuroanatomy, 2022
Originating from the brainstem raphe nuclei, serotonin is an important neuromodulator involved in a variety of physiological and pathological functions.
Ildikó Piszár   +4 more
doaj   +1 more source

Stimulation of electro-olfactogram responses in the main olfactory epithelia by airflow depends on the type 3 adenylyl cyclase [PDF]

open access: yes, 2012
Cilia of olfactory sensory neurons are the primary sensory organelles for olfaction. The detection of odorants by the main olfactory epithelium (MOE) depends on coupling of odorant receptors to the type 3 adenylyl cyclase (AC3) in olfactory cilia.
Chen, Xuanmao   +2 more
core   +2 more sources

Top-down feedback enables flexible coding strategies in the olfactory cortex

open access: yesCell Reports, 2022
Summary: In chemical sensation, multiple models have been proposed to explain how odors are represented in the olfactory cortex. One hypothesis is that the combinatorial identity of active neurons within sniff-related time windows is critical, whereas ...
Zhen Chen, Krishnan Padmanabhan
doaj   +1 more source

The cell cycle–apoptosis connection revisited in the adult brain [PDF]

open access: yes, 2005
Adult neurogenesis is studied in vivo using thymidine analogues such as bromodeoxyuridine (BrdU) to label DNA synthesis during the S phase of the cell cycle.
Bauer, Sylvian, Patterson, Paul H.
core   +3 more sources

Exploring Nasal Structural‐Microbial Interactions in Multiple Sclerosis‐Associated Olfactory Impairment

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Olfactory dysfunction is frequently observed in patients with multiple sclerosis (MS); however, its underlying mechanisms remain poorly understood. To date, no studies have directly examined the nasal mucosal microbiota in MS. This study aimed to explore potential relationships among olfactory function, nasal microbiota composition,
Zidan Gao   +5 more
wiley   +1 more source

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