Results 81 to 90 of about 497,866 (292)

Neuromorphic Devices and Computing for Sensing, Memory, and Control

open access: yesAdvanced Science, EarlyView.
This review introduces neuromorphic devices made from diverse materials. These devices mimic neuronal functions and architectures and, when integrated with artificial or biological computing, can form closed loops with neurons for pressure, optical, acoustic, and biochemical sensing and modulation.
Zhengguang Zhu   +2 more
wiley   +1 more source

Characterizing functional pathways of the human olfactory system

open access: yeseLife, 2019
The central processing pathways of the human olfactory system are not fully understood. The olfactory bulb projects directly to a number of cortical brain structures, but the distinct networks formed by projections from each of these structures to the ...
Guangyu Zhou   +4 more
doaj   +1 more source

Subventricular zone stem cells are heterogeneous with respect to their embryonic origins and neurogenic fates in the adult olfactory bulb [PDF]

open access: yes, 2007
Wedetermined the embryonic origins of adult forebrain subventricular zone (SVZ) stem cells by Cre-lox fate mapping in transgenic mice. We found that all parts of the telencephalic neuroepithelium, including the medial ganglionic eminence and lateral ...
Richardson, WD   +3 more
core  

Optophysiological analysis of pattern classification strategies in the zebrafish olfactory bulb [PDF]

open access: yes, 2012
Classification of overlapping activity patterns is a common problem for sensory systems. For a robust representation of sensory stimuli, neuronal circuits should generalize over input patterns reflecting variations of the same stimulus but separate ...
Niessing, Jörn
core   +1 more source

Top-Down Feedback Enables Flexible Coding Strategies in Olfactory Cortex

open access: yes, 2022
In chemical sensation, multiple models have been proposed to explain how odors are represented in olfactory cortex. One hypothesis is that the combinatorial identity of active neurons within sniff-related time windows is critical, whereas another model ...
Chen, Zhen, Padmanabhan, Krishnan
core   +1 more source

Entorhinal Astrocyte Transplants Restore Spatial Exploration and Alleviate Amyloid‐Beta Pathology in Alzheimer's Mice

open access: yesAdvanced Science, EarlyView.
Impaired MEC astrocytic Ca2+ signaling is associated with fragmented spatial exploration in AD mice. Region‐specific glial progenitor transplantation generates engrafted astrocytes that are accompanied by improved AQP4 polarization, reduced amyloid‐β‐associated pathology, attenuated neuroinflammation, preserved synaptic integrity, and ameliorated ...
Fengjuan Wu   +16 more
wiley   +1 more source

Neural Circuit Dynamics and Ensemble Coding in the Locust and Fruit Fly Olfactory System [PDF]

open access: yes, 2007
Raw sensory information is usually processed and reformatted by an organism’s brain to carry out tasks like identification, discrimination, tracking and storage.
Jayaraman, Vivek
core   +1 more source

Grtp1 Safeguards Against Paternal Reproductive Aging and Intergenerational Behavioral Deficits by Preserving Redox Homeostasis

open access: yesAdvanced Science, EarlyView.
This study identifies that Grtp1 maintains germline redox homeostasis by interacting with PRDX1/4‐TXN to antagonize paternal reproductive aging. Growth hormone restores Grtp1 expression, rectifies aberrant sperm DNA methylation, and ameliorates intergenerational anxiety and social deficits, highlighting the GH‐GRTP1 axis as a promising intervention ...
Yingdong Liu   +23 more
wiley   +1 more source

Molecular signatures of neural connectivity in the olfactory cortex [PDF]

open access: yesNature Communications, 2016
AbstractThe ability to target subclasses of neurons with defined connectivity is crucial for uncovering neural circuit functions. The olfactory (piriform) cortex is thought to generate odour percepts and memories, and odour information encoded in piriform is routed to target brain areas involved in multimodal sensory integration, cognition and motor ...
Diodato, Assunta   +9 more
openaire   +5 more sources

TH/TRs–COL11A2 Axis Mediates Loss of a Differentiated Astrocyte State in Hypogyrified Brains

open access: yesAdvanced Science, EarlyView.
Using a gyrencephalic congenital hypothyroidism pig model, this study reveals cerebral atrophy and cortical hypogyrification. Single‐cell sequencing identifies astrocytes as major TH‐responsive cells, with the COL11A2‐enriched Astro‐2 state nearly absent.
Ying Zhang   +14 more
wiley   +1 more source

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