Results 91 to 100 of about 477,767 (296)

Molecular signatures of neural connectivity in the olfactory cortex [PDF]

Nature Communications, 2016
AbstractThe ability to target subclasses of neurons with defined connectivity is crucial for uncovering neural circuit functions. The olfactory (piriform) cortex is thought to generate odour percepts and memories, and odour information encoded in piriform is routed to target brain areas involved in multimodal sensory integration, cognition and motor ...
Diodato, Assunta, Ruinart de Brimont, Marion, Yim, Yeong Shin, Derian, Nicolas, Perrin, Sandrine, Pouch, Juliette, Klatzmann, David, Garel, Sonia, Choi, Gloria B., Fleischmann, Alexander   +9 more
openaire   +5 more sources

Exploring olfactory sensory networks: Simulations and hardware emulation [PDF]

, 2010
Olfactory stimuli are represented in a highdimensional space by neural networks of the olfactory system. A great deal of research in olfaction has focused on this representation within the first processing stage, the olfactory bulb (vertebrates) or ...
Beyeler, Michael, Galizia, G, Fabio Stefanini, Henning Proske, Beyeler, M., Chicca, Elisabetta, Proske, H., Giovanni Galizia, Beyeler, M, Michael Beyeler, Chicca, E, Galizia, C. Giovanni, Stefanini, F., Proske, Henning, Proske, H, Elisabetta Chicca, Galizia, G., Stefanini, Fabio, Chicca, Elisabetta ; https://orcid.org/, Stefanini, F   +19 more
core   +1 more source

SemanticST: A Scalable Multi‐Contextual Graph Learning Framework for Uncovering Spatial Niches and Robust Multi‐Sample Integration in Spatial Transcriptomics

Advanced Science, EarlyView.
Technical limitations often let dominant signals overshadow rare cell types and fine‐grained heterogeneity in spatial transcriptomics. SemanticST, a graph neural network using multi‐semantic graph fusion and a novel min‐cut loss, recovers these subtle patterns.
Roxana Zahedi, Ahmadreza Argha, Nona Farbehi, Ivan Bakhshayeshi, Thantrira Porntaveetus, Youqiong Ye, Nigel H. Lovell, Hamid Alinejad‐Rokny   +7 more
wiley   +1 more source

Endothelial miR‐15a/16‐1 Regulation of SYNE1 Mediates Structural and Functional Recovery after Traumatic Brain Injury

Advanced Science, EarlyView.
Endothelial miR‐15a/16‐1 deletion promotes long‐term recovery after traumatic brain injury by restoring SYNE1 expression. Enhanced endothelial SYNE1 preserves vascular integrity, protects white and gray matter, and improves neurological function. The endothelial miR‐15a/16‐1–SYNE1 axis emerges as a key regulator of neurovascular repair and a potential ...
Shun Li, Na Qiu, Chao Zhou, Andrew Ni, Ping Sun, Jia‐Jun Liu, Xin‐Lei Huang, Tian‐Qing Xiong, Yu‐Chi Zhang, Hai‐Zhou Liu, Xiao‐Tao Xu, Rui Wang, Shi‐Qing Zhang, Yu‐Xin Zhang, Silvia Liu, C. Edward Dixon, Jun Chen, Ke‐Jie Yin   +17 more
wiley   +1 more source

Trajectory of olfactory cortex degeneration from normal cognition to Alzheimer's disease: Insights from multimodal neuroimaging

Neurobiology of Disease
Objective: The olfactory cortex is among the earliest brain regions affected by Alzheimer's disease (AD), with olfactory deficits frequently preceding cognitive decline.
Simin Yang, Bo Xie, Dan Liao, Yuejiao Sun, Zhuo Wang, Huimao Zhang, Yu Yang, Chunjie Guo   +7 more
doaj   +1 more source

Neuromorphic Devices and Computing for Sensing, Memory, and Control

Advanced Science, EarlyView.
This review introduces neuromorphic devices made from diverse materials. These devices mimic neuronal functions and architectures and, when integrated with artificial or biological computing, can form closed loops with neurons for pressure, optical, acoustic, and biochemical sensing and modulation.
Zhengguang Zhu, Nicholas Schaffer, Xiao Yang   +2 more
wiley   +1 more source

Reconstruction of neuronal activity and connectivity patterns in the zebrafish olfactory bulb [PDF]

, 2016
In the olfactory bulb (OB), odors evoke distributed patterns of activity across glomeruli that are reorganized by networks of interneurons (INs). This reorganization results in multiple computations including a decorrelation of activity patterns across ...
Wanner, Adrian A.
core   +1 more source

Entorhinal Astrocyte Transplants Restore Spatial Exploration and Alleviate Amyloid‐Beta Pathology in Alzheimer's Mice

Advanced Science, EarlyView.
Impaired MEC astrocytic Ca2+ signaling is associated with fragmented spatial exploration in AD mice. Region‐specific glial progenitor transplantation generates engrafted astrocytes that are accompanied by improved AQP4 polarization, reduced amyloid‐β‐associated pathology, attenuated neuroinflammation, preserved synaptic integrity, and ameliorated ...
Fengjuan Wu, Jihua Fan, Xiang Zhou, Zhiqi Yang, Mingyue Gong, Mingzhu Huang, Zhenlu Cai, Shaofan Yang, Teng Teng, Chuanyan Yang, Jin Li, Haoyu Wang, Shuangshuang Dai, Chunhai Chen, Xiaowei Chen, Manxia Wang, Kuan Zhang   +16 more
wiley   +1 more source

Wiring olfaction: the cellular and molecular mechanisms that guide the development of synaptic connections from the nose to the cortex

Frontiers in Neuroscience, 2009
Within the central nervous system, the olfactory system fascinates by its developmental and physiological particularities, and is one of the most studied models to understand the mechanisms underlying the guidance of growing axons to their appropriate ...
Fernando De Castro
doaj   +1 more source

State-Dependent Sensory Gating in Olfactory Cortex [PDF]

, 2005
SummarySensory systems show behavioral state-dependent gating of information flow that largely depends on the thalamus. Here we examined whether the state-dependent gating occurs in the central olfactory pathway that lacks a thalamic relay.
Murakami, Masayoshi, Kensaku Mori, Kirino, Yutaka, Hideki Kashiwadani, Yutaka Kirino, Masayoshi Murakami, Kashiwadani, Hideki, Mori, Kensaku   +7 more
core   +1 more source