Results 111 to 120 of about 52,033 (255)

Sensory Neuroscience—Charting the Course From Molecular Mechanisms to Clinical Translation

Sensory Neuroscience, EarlyView.
Renjie Chai
wiley   +1 more source

Human brain matters: Navigating the neuropathology of COVID‐19

Brain Pathology, EarlyView.
Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland, Angelica Scaramuzza, Marianna Bugiani, Wilma D. J. van de Berg, Jinte Middeldorp   +4 more
wiley   +1 more source

Zeb2 Controls Retinal Physiological and Pathological Angiogenesis by Regulating Astrocyte Proliferation and Differentiation

Cell Proliferation, EarlyView.
During development, the oxygen‐sensitive transcription factor Zeb2 restrains astrocyte proliferation and maturation to ensure balanced retinal angiogenesis. In disease, it promotes the neurotoxic A1 astrocyte phenotype and inflammation, thereby promoting reparative revascularization over pathological neovascularization.
Jing Liu, Yanan Guo, Kangjian Xiang, Shuyi Wang, Dongchang Xiao, Mengqing Xiang   +5 more
wiley   +1 more source

Impacts of Ocean Acidification on Reproduction and Early Life Development in Marine Teleost Fish—A Synthesis

Fish and Fisheries, EarlyView.
ABSTRACT Ocean acidification (OA) remains a major and underexplored threat to marine fishes, particularly regarding reproductive physiology and early life stages (ELS). Although research over the past 15 years has documented diverse OA effects, substantial knowledge gaps persist.
Rebecca J. Bridge, Benjamin T. McClelland, Silvana N. R. Birchenough, Martina H. Stiasny   +3 more
wiley   +1 more source

Proteostasis of organelles in aging and disease

The FEBS Journal, EarlyView.
Cells rely on regulated proteostasis mechanisms to keep their internal compartments functioning properly. When these mechanisms fail, damaged proteins accumulate, disrupting organelles, such as the nucleus, mitochondria, endoplasmic reticulum, Golgi, and lysosomes, as well as membraneless organelles, such as stress granules, processing bodies, the ...
Yara Nabawi, Cansu Doğan, Dunja Petrović, Gülce Perçin, Seda Koyuncu, David Vilchez   +5 more
wiley   +1 more source

Olfactory dysfunction as a marker of neurodegenerative disease in older adults. [PDF]

Aging Clin Exp Res
Klíčová K, Menšíková K, Šebelová D, Polčáková P, Kaleta M, Cook SEV, Ildžová Z, Satke L, Zimek D, Kaňovský P.   +9 more
europepmc   +1 more source

Transcriptional responses of Aedes aegypti chemosensory tissues in response to volatile DEET and citronella oil

Insect Molecular Biology, EarlyView.
Aedes aegypti females were significantly repelled by both volatile DEET and citronella oil in comparison to control (ethanol‐exposed) mosquitoes. Global gene expression changes were largest in the mosquito mouthparts, with notable downregulation of the three subunits comprising the mosquito CO2 receptor (Gr1, 2 and 3).
Ivan Drahun, Jessica M. Sparrow, Cody W. Koloski, Bryan J. Cassone   +3 more
wiley   +1 more source

Study on the pathogenesis of PLXNB1 gene in olfactory dysfunction of allergic rhinitis. [PDF]

PLoS One
Chen X, Zhao L, Luo W.
europepmc   +1 more source

Neural correlates of pure apathy in multiple sclerosis: An exploratory neuroimaging study

Journal of Neuropsychology, EarlyView.
Abstract Pure apathy is relatively common in people with Multiple Sclerosis (PwMS), but its neural mechanisms remain unexplored. Therefore, we investigated the neural correlates of pure apathy in PwMS, differentiating it from depression. Sixty‐two PwMS underwent neuropsychological assessments and Magnetic Resonance Imaging scans.
Valentina Torchia, Vera Gramigna, Mariachiara Gaita, Daniele Spitaleri, Antonio Costanzo, Liana Palermo, Florindo d'Onofrio, Simona Raimo   +7 more
wiley   +1 more source

Comparative Characterization of Olfactory Dysfunction in Mouse Models of Eosinophilic Chronic Rhinosinusitis. [PDF]

Cells
Dekeyser A, Lecocq M, Camboni A, Gohy S, Pilette C, Lin B, Huart C, Hox V.   +7 more
europepmc   +1 more source