Results 121 to 130 of about 54,861 (297)
Movement Disorders Clinical Practice, EarlyView.Abstract Background Parkinson's Disease (PD) is a progressive neurodegenerative disorder primarily characterized by motor symptoms such as tremors, rigidity, and bradykinesia. Structural brain changes, including atrophy in the midbrain, basal ganglia, and cortical regions such as the frontal and temporal lobes, are observed in advanced stages.
Suraiya Mangra +5 more
wiley +1 more source
Presbyosmia, Parkinson’s and Pharmaceutically-induced loss of olfactory function
, 2007 Olfactory function is impaired in the majority of persons with Parkinson's disease (PD). Olfactory dysfunction occurs early in the disease and is a proposed means of premorbid disease detection. However, the level of olfactory impairment is not universal
Burne, Thomas +3 more
core
, 2016 General characteristics of participants with normal olfactory function and participants with olfactory dysfunction.
Hyo Geun Choi (668708) +5 more
core +1 more source
Movement Disorders Clinical Practice, EarlyView.Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz +2 more
wiley +1 more source
Olfactory dysfunction in Alzheimer's disease.
Neuropsychiatric disease and treatment, 2016 Alzheimer's disease (AD) is a common neurodegenerative disorder with the earliest clinical symptom of olfactory dysfunction, which is a potential clinical marker for AD severity and progression. However, many questions remain unanswered. This article reviews relevant research on olfactory dysfunction in AD and evaluates the predictive value of ...
Zou, Yong-ming +4 more
openaire +2 more sources
Radiological Diagnosis for Posttraumatic Olfactory Dysfunction [PDF]
, 2000 Objective : To evaluate objectively the sites of injury in patients with posttraumatic olfactory deficits and to suggest the diagnostic procedure for evaluation of posttraumatic anosmia.
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When the Scale Drops: Pathways to Weight Loss in Parkinson's Disease and Future Directions
Movement Disorders, EarlyView.Abstract Although Parkinson's disease (PD) is classically defined by its motor features, non‐motor symptoms exert a substantial and often under‐recognized influence on disease trajectory. Among these, weight loss has long been observed in PD and other neurodegenerative disorders, yet the mechanisms remain incompletely understood.
Ellie D. Gabriel +6 more
wiley +1 more source
Movement Disorders, EarlyView.Abstract Parkinson's disease (PD) has been historically defined as a disease of striatal dopamine deficiency secondary to degeneration of dopaminergic neurons in the substantia nigra pars compacta, related to the presence of Lewy bodies and Lewy neurites.
Michele Matarazzo +10 more
wiley +1 more source
Movement Disorders, EarlyView.Abstract Background Although clinical markers (eg, motor and cognitive impairment) in isolated rapid eye movement sleep behavior disorder (iRBD) are associated with faster phenoconversion, their longitudinal trajectory patterns (linear or nonlinear) remain unclear.
Li Zhou +17 more
wiley +1 more source
Linkage between increased nociception and olfaction via a SCN9A haplotype
, 2013 Background and Aims: Mutations reducing the function of Nav1.7 sodium channels entail diminished pain perception and olfactory acuity, suggesting a link between nociception and olfaction at ion channel level.
Hummel, Thomas +9 more
core +1 more source