Results 171 to 180 of about 50,072 (244)

Cerebral Small Vessel Disease in Older Adults With Olfactory Dysfunction. [PDF]

open access: yesInt Forum Allergy Rhinol
Eckert MA   +3 more
europepmc   +1 more source

The Microbiota Shapes Central Nervous System Myelination in Early Life

open access: yesAdvanced Science, Volume 13, Issue 14, 9 March 2026.
Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch   +13 more
wiley   +1 more source

Monoaminylation in Human Health and Disease: State of the Field, Challenges, and Emerging Directions

open access: yesAdvanced Science, Volume 13, Issue 16, 18 March 2026.
This review delineates monoaminylation—serotonylation, dopaminylation, and histaminylation—as key post‐translational modifications beyond receptor signaling. It details their catalytic mechanisms, roles in gene expression and protein function, and implications in health and disease, aiming to bridge mechanistic insights with therapeutic potential ...
Yiqi Zhao   +4 more
wiley   +1 more source

Treg Cells Modulate Neuroinflammation and Behavioral Deficits in Autism: Evidence From MR‐Based Genetic Analyses and Experimental Models

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 201, Issue 2, Page 127-143, March 2026.
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental condition that is increasingly linked to immune dysfunction and neuroinflammation. Regulatory T cells (Tregs), which are crucial in maintaining immune homeostasis, have been implicated in the pathogenesis of ASD.
Zuqing Nie   +9 more
wiley   +1 more source

The sex‐specific association between long‐term PM2.5 exposure and incident dementia in community‐dwelling older adults in Australia

open access: yesAlzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION Air pollution is linked to dementia, but evidence from low‐exposure settings is limited. We examined sex‐specific associations between long‐term exposure to fine particulate matter ≤2.5 µm in diameter (PM2.5) and dementia risk in older adults living in Australia.
Aoshuang Zhou   +9 more
wiley   +1 more source

Sex and life experience shape locus coeruleus pretangle tau pathology

open access: yesAlzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION Alzheimer's disease features early a pathology in the locus coeruleus (LC), yet how sex and life experience shape LC vulnerability remains poorly understood. METHODS We expressed pseudophosphorylated human tau (htauE14) in LC neurons of TH‐Cre rats and exposed both sexes to early‐ or late‐life enrichment or stress.
Zia Hasan   +10 more
wiley   +1 more source

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