Results 171 to 180 of about 50,072 (244)
Cerebral Small Vessel Disease in Older Adults With Olfactory Dysfunction. [PDF]
Eckert MA +3 more
europepmc +1 more source
The Microbiota Shapes Central Nervous System Myelination in Early Life
Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch +13 more
wiley +1 more source
Monoaminylation in Human Health and Disease: State of the Field, Challenges, and Emerging Directions
This review delineates monoaminylation—serotonylation, dopaminylation, and histaminylation—as key post‐translational modifications beyond receptor signaling. It details their catalytic mechanisms, roles in gene expression and protein function, and implications in health and disease, aiming to bridge mechanistic insights with therapeutic potential ...
Yiqi Zhao +4 more
wiley +1 more source
Efficacy of Platelet Rich Plasma Versus Placebo for Improvement in Olfactory Function in Adults With Olfactory Dysfunction: A Systematic Review and Meta-Analysis. [PDF]
Jafar AB +4 more
europepmc +1 more source
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental condition that is increasingly linked to immune dysfunction and neuroinflammation. Regulatory T cells (Tregs), which are crucial in maintaining immune homeostasis, have been implicated in the pathogenesis of ASD.
Zuqing Nie +9 more
wiley +1 more source
An unexpected insight into the cause of olfactory dysfunction: fibrillogenesis of odorant-binding proteins. [PDF]
Stepanenko OV +3 more
europepmc +1 more source
Abstract INTRODUCTION Air pollution is linked to dementia, but evidence from low‐exposure settings is limited. We examined sex‐specific associations between long‐term exposure to fine particulate matter ≤2.5 µm in diameter (PM2.5) and dementia risk in older adults living in Australia.
Aoshuang Zhou +9 more
wiley +1 more source
Supervised Machine Learning Analysis of Food-Related Quality of Life Impact in Olfactory Dysfunction. [PDF]
Bayer K +4 more
europepmc +1 more source
Sex and life experience shape locus coeruleus pretangle tau pathology
Abstract INTRODUCTION Alzheimer's disease features early a pathology in the locus coeruleus (LC), yet how sex and life experience shape LC vulnerability remains poorly understood. METHODS We expressed pseudophosphorylated human tau (htauE14) in LC neurons of TH‐Cre rats and exposed both sexes to early‐ or late‐life enrichment or stress.
Zia Hasan +10 more
wiley +1 more source

