Results 81 to 90 of about 7,510,662 (182)
Genome Research, 2014 Olfactory receptors (ORs) detect odors in the environment, and OR genes constitute the largest multigene family in mammals. Numbers of OR genes vary greatly among species—reflecting the respective species' lifestyles—and this variation is caused by ...
Y. Niimura, A. Matsui, K. Touhara
semanticscholar +1 more source
Cell Stem Cell, 2019 Summary Although olfactory mucosa possesses long-lived horizontal basal stem cells (HBCs) and remarkable regenerative capacity, the function of human olfactory neuroepithelium is significantly impaired in chronic inflammatory rhinosinusitis. Here we show
Mengfei Chen, R. Reed, A. Lane
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Signatures of Selection in the Human Olfactory Receptor OR5I1 Gene [PDF]
Molecular Biology and Evolution, 2007 The human olfactory receptor (OR) repertoire is reduced in comparison to other mammals and to other nonhuman primates. Nonetheless, this olfactory decline opens an opportunity for evolutionary innovation and improvement. In the present study, we focus on an OR gene, OR5I1, which had previously been shown to present an excess of amino acid replacement ...
Moreno Estrada, Andrés +6 more
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Parental olfactory experience influences behavior and neural structure in subsequent generations
Nature Neuroscience, 2013 Using olfactory molecular specificity, we examined the inheritance of parental traumatic exposure, a phenomenon that has been frequently observed, but not understood.
B. Dias, K. Ressler
semanticscholar +1 more source
Transcriptome sequencing of olfactory-related genes in olfactory transduction of large yellow croaker (Larimichthy crocea) in response to bile salts [PDF]
PeerJ, 2019 Fish produce and release bile salts as chemical signalling substances that act as sensitive olfactory stimuli. To investigate how bile salts affect olfactory signal transduction in large yellow croaker (Larimichthy crocea), deep sequencing of olfactory ...
Jiabao Hu +10 more
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Olfactory receptor genes cooperate with protocadherin genes in human extreme obesity [PDF]
Genes & Nutrition, 2015 Worldwide, the incidence of obesity has increased dramatically over the past decades. More knowledge about the complex etiology of obesity is needed in order to find additional approaches for treatment and prevention. Investigating the exome sequencing data of 30 extremely obese subjects (BMI 45-65 kg/m(2)) shows that predicted damaging missense ...
Edwin C. M. Mariman +5 more
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Cell Reports, 2018 SUMMARY Cellular heterogeneity within the mammalian brain poses a challenge toward understanding its complex functions. Within the olfactory bulb, odor information is processed by subtypes of inhibitory interneurons whose heterogeneity and functionality ...
Burak Tepe +6 more
semanticscholar +1 more source
Odorant receptor genes are expressed in olfactory neuroblastoma
Genetics and Molecular Research, 2013 Olfactory neuroblastoma (ONB) is a malignant tumor found in the human nasal cavity. These tumors are rare and poorly characterized at the molecular level. In this study, we asked whether olfactory-specific genes are expressed in ONBs by using reverse-transcriptase-polymerase chain reaction.
D C, Gonzalez-Kristeller +5 more
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Frontiers in Psychology, 2014 The molecular mechanism of olfactory cognition is very complicated. Olfactory cognition is initiated by olfactory receptor proteins (odorant receptors), which are activated by olfactory stimuli (ligands). Olfactory receptors are the initial player in the
Elena V. Ignatieva +10 more
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Frontiers in Cell and Developmental BiologyIntroductionOlfaction is important for the quality of life; however, in Kallmann syndrome (KS), defective development results in olfactory dysfunction.
Bo-Ra Kim +10 more
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