Results 101 to 110 of about 69,587 (287)

The Genomic Structure of Human Olfactory Receptor Genes

Genomics, 2000
The genomic and cDNA structures were studied for eight human olfactory receptor (OR) genes within the chromosome 17p13.3 cluster. A common gene structure was revealed, which included an approximately 1-kb intronless coding region terminated by a signal for polyadenylation and a variable number of upstream noncoding exons.
A, Sosinsky, G, Glusman, D, Lancet
openaire   +2 more sources

The complete swine olfactory subgenome: expansion of the olfactory gene repertoire in the pig genome [PDF]

BMC Genomics, 2012
Abstract Background Insects and animals can recognize surrounding environments by detecting thousands of chemical odorants. Olfaction is a complicated process that begins in the olfactory epithelium with the specific binding of volatile odorant molecules to dedicated olfactory receptors (ORs).
Nguyen Dinh, Lee Kyooyeol, Choi Hojun, Choi Min-kyeung, Le Minh, Song Ning, Kim Jin-Hoi, Seo Han, Oh Jae-Wook, Lee Kyungtae, Kim Tae-Hun, Park Chankyu   +11 more
openaire   +3 more sources

Olfactory Genes Lie in a Mutational Hot Spot [PDF]

, 2013
Substitution rates of the olfactory genes in the central region of human Chromosome 11. The substitution rate of ancestral repeat sequences is higher in the region where the olfactory genes lie.
Jeffrey H Chuang (55725), Hao Li (31608)
core   +1 more source

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

Changes in maternal gene expression in olfactory circuits in the immediate postpartum period.

Frontiers in Psychiatry, 2011
Regulation of maternal behavior in the immediate postpartum period involves neural circuits in reward and homeostasis systems responding to cues from the newborn.
Sofija V Canavan, Linda eMayes, Helen B Treloar   +2 more
doaj   +1 more source

Open housing drives the expression of immune response genes in the nasal mucosa, but not the olfactory bulb. [PDF]

PLoS ONE, 2017
Nasal mucosa and olfactory bulb are separated by the cribriform plate which is perforated by olfactory nerves. We have previously demonstrated that the cribriform plate is permissive for T cells and monocytes and that viruses can enter the bulb upon ...
Carolin Piotrowski, Vera Lede, Anne Butthof, Nicole Kaiser, Petra G Hirrlinger, Matthias H Tschöp, Torsten Schöneberg, Ingo Bechmann   +7 more
doaj   +1 more source

Pax6 interactions with chromatin and identification of its novel direct target genes in lens and forebrain. [PDF]

, 2013
Pax6 encodes a specific DNA-binding transcription factor that regulates the development of multiple organs, including the eye, brain and pancreas. Previous studies have shown that Pax6 regulates the entire process of ocular lens development.
Tessa Walcher, Jovica Ninkovic (104237), David C Beebe, Deyou Zheng (7943), Ying Yang (24175), Xie, Q., Jie Huang, Louise Wolf (104240), Ariel Vitenzon (104242), Vitenzon, Ariel, Magdalena Götz, Zavadil, J., Wolf, L., Deyou Zheng, Götz, M., Yang, Ying, Ales Cvekl, Wolf, Louise, Tessa Walcher (104238), Yang, Y., Cvekl, A., Zheng, D.Y., Louise Wolf, Ninkovic, J., Jovica Ninkovic, Ariel Vitenzon, Götz, Magdalena, Jiri Zavadil (10270), Walcher, Tessa, Magdalena Götz (32199), Zavadil, Jiri, Qing Xie, Ninkovic, Jovica, Walcher, T., David C. Beebe (104247), Beebe, D.C., Zheng, Deyou, Huang, Jie, Cvekl, Ales, David C. Beebe, Xie, Qing, Jie Huang (104235), Ales Cvekl (104250), Vitenzon, A., Beebe, David C., Qing Xie (104232), Ying Yang, Jiri Zavadil, Huang, J.   +48 more
core   +1 more source

A Brain‐Wide Atlas of Astrocytic Oxytocin Receptors Reveals a Glial Basis for Nucleus Accumbens Modulation of Affiliative Behavior

Advanced Science, EarlyView.
The cellular actors of oxytocin signaling are under intense scrutiny. A brain‐wide anatomical and functional analysis in mice and rats reveals widespread expression of oxytocin receptors in astrocytes. These receptors are functionally active and, in the nucleus accumbens, selectively regulate male social affiliation.
Clémence Denis, Stefan Stojilkovic, Kai‐Yi Wang, Cristina Márquez, Annabel C. Kleinwächter, Angel Baudon, Yuval Podpecan, Aurélia Ces, Mélanie Kremer, Isabelle Arnoux, Nathalie Rouach, Jemima Helen, Sophie Trender, Andreas Wallkum, Selina Wunsch, Franziska Schommer, Moritz C. Wimmer, Tim Schubert, Felix Franke, Jabir Aliyu Muhammad, Eva M. Eisemann, Ingrid Camila Possa‐Paranhos, Cassandra Baumann, Pierre‐Alexis Derrien, Quirin Krabichler, Cosmo Garcia, Henning Fröhlich, Matthew K. Kirchner, Valery Grinevich, Pascal Darbon, Javier E. Stern, Ferdinand Althammer, Alexandre Charlet   +32 more
wiley   +1 more source

Inventory of the cichlid olfactory receptor gene repertoires: identification of olfactory genes with more than one coding exon [PDF]

BMC Genomics, 2014
To help understand the molecular mechanisms underlying the remarkable phenotypic diversity displayed by cichlids, the genome sequences of O. niloticus, P. nyererei, H. burtoni, N. brichardi and M. zebra were recently determined. Here, we present the contents of the olfactory receptor (OR) repertoires in the genomes of these five fishes.We performed an ...
Azzouzi, Naoual, Barloy-Hubler, Frederique, Galibert, Francis   +2 more
openaire   +3 more sources

Chronic Cadmium Exposure Induces Impaired Olfactory Learning and Altered Brain Gene Expression in Honey Bees (Apis mellifera)

Insects, 2022
The honey bee (Apis mellifera) plays vital ecological roles in the pollination of crops and the maintenance of ecological balance, and adult honey bees may be exposed to exogenous chemicals including heavy metals during their foraging activities. Cadmium
Zhiguo Li, Yuanmei Qiu, Jing Li, Kunlin Wan, Hongyi Nie, Songkun Su   +5 more
doaj   +1 more source