Dupilumab Dampens Mucosal Type 2 Response During Acetylsalicylic Acid Challenge in N‐ERD Patients
Clinical &Experimental Allergy, EarlyView.Dupilumab therapy reduced elevated type 2 cytokine responses post‐ASA provocation in N‐ERD patients, independent of ASA tolerance, and revealed novel mechanistic insights by modulating acute type 2 immunity. Transcriptomic analysis showed concurrent downregulation of lipid and peroxisome pathways during ASA challenge in N‐ERD patients after 24 weeks of
Julia Eckl‐Dorna +10 more
wiley +1 more source
Common olfactory ensheathing glial markers in the developing human olfactory system [PDF]
, 2016 The in situ immunocytochemical properties of olfactory ensheathing cells (OECs) have been well studied in several small to medium sized animal models including rats, mice, guinea pigs, cats and canines.
Choi, D, Cotfas, D, Oprych, K
core +1 more source
OLFACTORY BULB POTENTIALS TO ELECTRICAL STIMULATION OF THE OLFACTORY MUCOSA
The Japanese Journal of Physiology, 1961 The properties of the olfactory bulb potential evoked by electrical stimulation of the olfactory mucosa were studied in rabbits immobilized with d-tubocurarine. The evoked potential was a slow negative wave when recorded from the surface of the bulb.
openaire +3 more sources
Artificial intelligence‐powered microscopy: Transforming the landscape of parasitology
Journal of Microscopy, EarlyView.Abstract Microscopy and image analysis play a vital role in parasitology research; they are critical for identifying parasitic organisms and elucidating their complex life cycles. Despite major advancements in imaging and analysis, several challenges remain. These include the integration of interdisciplinary data; information derived from various model
Mariana De Niz +4 more
wiley +1 more source
Detection of inflammation- and neoplasia-associated alterations in human large intestine using plant/invertebrate lectins, galectin-1 and neoglycoproteins [PDF]
, 1998 Commonly, plant and invertebrate lectins are accepted glycohistochemical tools for the analysis of normal and altered structures of glycans in histology and pathology.
Bosbach, R. +3 more
core +1 more source
Anatomy of spinal CSF loss in the American alligator (Alligator mississippiensis)
Journal of Anatomy, Volume 246, Issue 4, Page 575-584, April 2025.India ink introduced into the cranial cerebrospinal fluid (CSF) compartment of Alligator diffuses along the spinal cord and exits the spinal compartment using perineural flow, resulting in a prominent “ink cuff” forming at the base of the spinal nerve. In Alligator, the region of the ink cuff is drained by a small lymphatic vessel.
Hadyn DeLeeuw +5 more
wiley +1 more source
Olfactory ensheathing glia are required for embryonic olfactory axon targeting and the migration of gonadotropin-releasing hormone neurons. [PDF]
, 2013 Kallmann's syndrome is caused by the failure of olfactory axons and gonadotropin-releasing hormone (GnRH) neurons to enter the embryonic forebrain, resulting in anosmia and sterility.
Baker, Clare VH +4 more
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Single‐Dose Pharmacokinetics of Intranasal Levetiracetam in Healthy Dogs
Journal of Veterinary Pharmacology and Therapeutics, EarlyView.ABSTRACT Cluster seizures and status epilepticus in dogs are emergencies requiring rapid intervention. Intranasal (IN) benzodiazepines are effective for early seizure cessation, but the pharmacokinetics of longer‐acting antiseizure medications administered IN have not been investigated in dogs.
Jessica L. Wagner +3 more
wiley +1 more source
The dual origin of the peripheral olfactory system: placode and neural crest
Molecular Brain, 2011 Background The olfactory epithelium (OE) has a unique capacity for continuous neurogenesis, extending axons to the olfactory bulb with the assistance of olfactory ensheathing cells (OECs).
Katoh Hiroyuki +11 more
doaj +1 more source
Microbial Contributions to Primate Reproduction
Evolutionary Anthropology: Issues, News, and Reviews, Volume 35, Issue 1, March 2026.ABSTRACT Reproduction is a complex process, and microbes play a far greater role than previously imagined. This review explores the ways that microbiomes influence the rich tapestry of reproductive processes and outcomes within the primate lineage, including pre‐copulatory and post‐copulatory mechanisms.
Silvia Carboni +2 more
wiley +1 more source