Characterizing functional pathways of the human olfactory system
eLife, 2019 The central processing pathways of the human olfactory system are not fully understood. The olfactory bulb projects directly to a number of cortical brain structures, but the distinct networks formed by projections from each of these structures to the ...
Guangyu Zhou +4 more
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Deconstructing Olfactory Epithelium Developmental Pathways in Olfactory Neuroblastoma
Cancer Research Communications, 2023 Olfactory neuroblastoma is a rare tumor arising from the olfactory cleft region of the nasal cavity. Because of the low incidence of this tumor, as well as an absence of established cell lines and murine models, understanding the mechanisms driving olfactory neuroblastoma pathobiology has been challenging.
John B. Finlay +4 more
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Disease-specific, neurosphere-derived cells as models for brain disorders [PDF]
, 2010 There is a pressing need for patient-derived cell models of brain diseases that are relevant and robust enough to produce the large quantities of cells required for molecular and functional analyses.
Abrahamsen, G. +29 more
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Induction of Associative Olfactory Memory by Targeted Activation of Single Olfactory Neurons in Drosophila Larvae [PDF]
, 2014 It has been postulated that associative memory is formed by at least two sets of external stimuli, CS and US, that are transmitted to the memory centers by distinctive conversing pathways.
Furukubo-Tokunaga Katsuo +5 more
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Cortical Magnetic Resonance Imaging Findings in Patients With Posttraumatic Olfactory Dysfunction: Comparison According to the Interval Between Trauma and Evaluation [PDF]
Clinical and Experimental Otorhinolaryngology, 2014 ObjectivesPatients with smell loss after craniocerebral trauma are known to have some brain abnormalities, but there was no study to analyze the findings according to the time interval between injury and evaluation.
Sang-Wook Kim +5 more
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Frontiers in Allergy, 2022 Chronic rhinosinusitis (CRS) is one of the most common causes of inflammation of the olfactory system, warranting investigation of the link between chronic inflammation and the loss of olfactory function.
Yi-Tsen Lin, Te-Huei Yeh, Te-Huei Yeh
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Cortically evoked motor responses in patients with Xp22.3-linked Kallmann's syndrome and in female gene carriers [PDF]
, 1992 Patients with Kallmann's syndrome show hypothalamic hypogonadism, hyposmia, and congenital mirror movements. As a correlate, a defect of gonadotropic neuron migration into the brain was recently detected. Considering abnormal outgrowth of neurons also as
Aizawa +33 more
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Data from Deconstructing Olfactory Epithelium Developmental Pathways in Olfactory Neuroblastoma
, 2023 <div><p>Olfactory neuroblastoma is a rare tumor arising from the olfactory cleft region of the nasal cavity. Because of the low incidence of this tumor, as well as an absence of established cell lines and murine models, understanding the mechanisms driving olfactory neuroblastoma pathobiology has been challenging.
Bradley J. Goldstein +4 more
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Pollen elicits proboscis extension but does not reinforce PER learning in honeybees [PDF]
, 2013 The function of pollen as a reward for foraging bees is little understood, though there is evidence to suggest that it can reinforce associations with visual and olfactory floral cues.
Casteel +10 more
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FIGURE 3 from Deconstructing Olfactory Epithelium Developmental Pathways in Olfactory Neuroblastoma
, 2023 <p>Patterns of gene expression in the normal differentiating OE. <b>A,</b> Trajectory UMAP depicting differentiation states across pseudotime, in seven normal olfactory mucosa biopsies scRNA-seq from Durante and colleagues, 2020 and Oliva and colleagues, 2021 (<a href="#bib13 bib24" target="_blank">13, 24</a>). <b>B,&
Bradley J. Goldstein +4 more
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