Results 21 to 30 of about 133,718 (290)

Figure S2 from Deconstructing Olfactory Epithelium Developmental Pathways in Olfactory Neuroblastoma

, 2023
<p>RNA expression signatures of ONB from Classe et al., 2018 based on markers traditionally associated with sinonasal undifferentiated carcinoma (A), small cell neuroendocrine carcinoma (B), and olfactory neuroblastoma (C), divided by control OE, low grade ONB, high grade ONB, and IDH2 mutant ONB.
Bradley J. Goldstein, Nosayaba Osazuwa-Peters, David W. Jang, Ralph Abi Hachem, John B. Finlay   +4 more
openaire   +1 more source

The V5A13.1 envelope glycoprotein deletion mutant of mouse hepatitis virus type-4 is neuroattenuated by its reduced rate of spread in the central nervous system. [PDF]

, 1992
Following intracerebral inoculation of adult Balb/c Byj mice, the MHV-4 strain of mouse hepatitis virus (MHV) had an LD50 of less than 0.1 PFU, whereas its monoclonal antibody resistant variant V5A13.1 had an LD50 of 10(4.2) PFU.
Bloom, F, Buchmeier, MJ, Fazakerley, JK, Parker, SE   +3 more
core   +1 more source

Figure S1 from Deconstructing Olfactory Epithelium Developmental Pathways in Olfactory Neuroblastoma

, 2023
<p>A and B identical to Figure 2A and B, but with the two IDH2 mutant tumors separated out from the other tumors into their own category. C shows estimated respiratory cell type proportions across normal OE, low grade, high grade, and IDH2 mutant tumors, which reveals that model estimates do not predict an increase in respiratory cell programming
Bradley J. Goldstein, Nosayaba Osazuwa-Peters, David W. Jang, Ralph Abi Hachem, John B. Finlay   +4 more
openaire   +1 more source

Mesenchymal/Epithelial Induction Mediates Olfactory Pathway Formation [PDF]

Neuron, 2000
In the olfactory pathway, as in the limbs, branchial arches, and heart, mesenchymal/epithelial induction, mediated by retinoic acid (RA), FGF8, sonic hedgehog (shh), and the BMPs, defines patterning, morphogenesis, and differentiation. Neuronal differentiation in the olfactory epithelium and directed growth of axons in the nascent olfactory nerve ...
LaMantia, Anthony-Samuel, Bhasin, Naina, Rhodes, Kattron, Heemskerk, Jill   +3 more
openaire   +2 more sources

Olfactory consciousness and gamma oscillation couplings across the olfactory bulb, olfactory cortex and orbitofrontal cortex

Frontiers in Psychology, 2013
The orbitofrontal cortex receives multi-modality sensory inputs, including olfactory input, and is thought to be involved in conscious perception of the olfactory image of objects.
Kensaku eMori, Kensaku eMori, Hiroyuki eManabe, Hiroyuki eManabe, Kimiya eNarikiyo, Kimiya eNarikiyo, Naomi eOnisawa, Naomi eOnisawa   +7 more
doaj   +1 more source

Transplantation of olfactory ensheathing cells into spinal cord lesions restores breathing and climbing [PDF]

, 2003
One of the most devastating effects of damage to the upper spinal cord is the loss of the ability to breathe; patients suffering these injuries can be kept alive only with assisted ventilation. No known method for repairing these injuries exists.
Decherchi, P., Li, Y., Raisman, G.
core   +2 more sources

FIGURE 4 from Deconstructing Olfactory Epithelium Developmental Pathways in Olfactory Neuroblastoma

, 2023
<p>PRC2 complex expression in ONB. <b>A,</b> PRC2 transcripts in the core complex are mostly upregulated in high-grade ONB. <b>B,</b> EPOP expression is significantly increased in high-grade ONB compared with low grade, with no differences between low and high grade in proteins that form the PRC2.2 complex.
Bradley J Goldstein, Nosayaba Osazuwa-Peters, David W Jang, Ralph Abi Hachem, John B Finlay   +4 more
openaire   +1 more source

MicroRNA Processing Pathway Regulates Olfactory Neuron Morphogenesis [PDF]

Current Biology, 2008
The microRNA (miRNA) processing pathway produces miRNAs as posttranscriptional regulators of gene expression. The nuclear RNase III Drosha catalyzes the first processing step together with the dsRNA binding protein DGCR8/Pasha generating pre-miRNAs [1, 2].
Berdnik, Daniela, Fan, Audrey P., Potter, Christopher J., Luo, Liqun   +3 more
openaire   +2 more sources

Decoding odor quality and intensity in the Drosophila brain [PDF]

, 2014
To internally reflect the sensory environment, animals create neural maps encoding the external stimulus space. From that primary neural code relevant information has to be extracted for accurate navigation.
Bausenwein, Brill, Caron, Chakraborty, Chen, Cichocki, Connolly, Couto, Datta, de Belle, Estes, Fiala, Fisek, Fishilevich, Grabe, Gupta, Heimbeck, Heisenberg, Hildebrand, Ito, Jefferis, Jefferis, Keene, Knaden, Kohl, Lai, Laissue, Larsson, Lee, Liang, Livingstone, Magee, Manni, Marin, Min, Murthy, Nakai, Nassi, Okada, Parnas, Pasternak, Patterson, Reidl, Roussel, Ruta, Rybak, Sanes, Semmelhack, Shang, Silbering, Steck, Stensmyr, Stocker, Stocker, Strutz, Stökl, Tanaka, Tian, Tully, Vosshall, Vosshall, Wang, Wang, Wang, Wilson, Wilson, Wilson, Wong   +67 more
core   +4 more sources

Cross‐talk between olfactory second messenger pathways [PDF]

European Journal of Biochemistry, 2000
The second messengers 3′‐5′‐cyclic‐monophosphate (cAMP) and inositol 1,4,5‐trisphosphate (InsP3) have been implicated in olfactory signal transduction in various species. The results of the present study provide evidence that the two olfactory second messenger pathways in rat olfactory neurons do not work independently but rather show a functional ...
A, Vogl, J, Noé, H, Breer, I, Boekhoff
openaire   +2 more sources