Results 1 to 10 of about 2,532,098 (296)

Ir76b is a Co-receptor for Amine Responses in Drosophila Olfactory Neurons

Frontiers in Cellular Neuroscience, 2021
Two large families of olfactory receptors, the Odorant Receptors (ORs) and Ionotropic Receptors (IRs), mediate responses to most odors in the insect olfactory system. Individual odorant binding “tuning” OrX receptors are expressed by olfactory neurons in
Alina Vulpe, Karen Menuz, Karen Menuz
doaj   +2 more sources

Mammalian olfactory receptors [PDF]

Frontiers in Cellular Neuroscience, 2009
Perception of chemical stimuli from the environment is essential to most animals; accordingly, they are equipped with a complex olfactory system capable of receiving a nearly unlimited number of odorous substances and pheromones. This enormous task is accomplished by olfactory sensory neurons (OSNs) arranged in several chemosensory compartments in the ...
Joerg Fleischer
openalex   +4 more sources

An epigenetic repressor TRIM66 dictates monogenic olfactory receptor expression, neural activity, and olfactory behavior [PDF]

Nature Communications
Olfactory receptor gene choice is an intricate example of monogenic and monoallelic expression, where one out of over 1000 receptor genes is transcribed in each olfactory sensory neuron.
Hongqiang Bao, Rong Liu, Yalei Kong, Penglai Liu, Jerome Kahiapo, Kangying Qian, Anan Li, Longzhi Tan, Qian Li   +8 more
doaj   +2 more sources

Profiling of olfactory receptor gene expression in whole human olfactory mucosa. [PDF]

PLoS ONE, 2014
Olfactory perception is mediated by a large array of olfactory receptor genes. The human genome contains 851 olfactory receptor gene loci. More than 50% of the loci are annotated as nonfunctional due to frame-disrupting mutations.
Christophe Verbeurgt, Françoise Wilkin, Maxime Tarabichi, Françoise Gregoire, Jacques E Dumont, Pierre Chatelain   +5 more
doaj   +2 more sources

Olfactory receptor pseudo-pseudogenes [PDF]

Nature, 2016
Pseudogenes are generally considered to be non-functional DNA sequences that arise through nonsense or frame-shift mutations of protein-coding genes.
Lucia L. Prieto-Godino, R. Rytz, Benoîte Bargeton, L. Abuin, J. R. Arguello, M. D. Peraro, M. D. Peraro, R. Benton   +7 more
semanticscholar   +5 more sources

Genetic basis of olfactory cognition: extremely high level of DNA sequence polymorphism in promoter regions of the human olfactory receptor genes revealed using the 1000 Genomes Project dataset

Frontiers in Psychology, 2014
The molecular mechanism of olfactory cognition is very complicated. Olfactory cognition is initiated by olfactory receptor proteins (odorant receptors), which are activated by olfactory stimuli (ligands). Olfactory receptors are the initial player in the
Elena V. Ignatieva, Elena V. Ignatieva, Victor G. Levitsky, Victor G. Levitsky, Nikolay S. Yudin, Nikolay S. Yudin, Mikhail P. Moshkin, Mikhail P. Moshkin, Nikolay A. Kolchanov, Nikolay A. Kolchanov, Nikolay A. Kolchanov   +10 more
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Ionotropic crustacean olfactory receptors. [PDF]

PLoS ONE, 2013
The nature of the olfactory receptor in crustaceans, a major group of arthropods, has remained elusive. We report that spiny lobsters, Panulirus argus, express ionotropic receptors (IRs), the insect chemosensory variants of ionotropic glutamate receptors.
Elizabeth A Corey, Yuriy Bobkov, Kirill Ukhanov, Barry W Ache   +3 more
doaj   +4 more sources

Asymmetric ephaptic inhibition between compartmentalized olfactory receptor neurons. [PDF]

Nature Communications, 2019
In the Drosophila antenna, different subtypes of olfactory receptor neurons (ORNs) housed in the same sensory hair (sensillum) can inhibit each other non-synaptically.
Bushong, Eric A, Chiang, Ann-Shyn, Chu, Li-An, Ellisman, Mark H, Reingruber, Jürgen, Su, Chih-Ying, Tsang, Tin Ki, Zhang, Ye   +7 more
core   +4 more sources

Chemoreceptor co-expression in Drosophila melanogaster olfactory neurons

eLife, 2022
Drosophila melanogaster olfactory neurons have long been thought to express only one chemosensory receptor gene family. There are two main olfactory receptor gene families in Drosophila, the odorant receptors (ORs) and the ionotropic receptors (IRs). The
Darya Task, Chun-Chieh Lin, Alina Vulpe, Ali Afify, Sydney Ballou, Maria Brbic, Philipp Schlegel, Joshua Raji, Gregory SXE Jefferis, Hongjie Li, Karen Menuz, Christopher J Potter   +11 more
doaj   +2 more sources

Adaptation of olfactory receptor abundances for efficient coding

eLife, 2019
Olfactory receptor usage is highly heterogeneous, with some receptor types being orders of magnitude more abundant than others. We propose an explanation for this striking fact: the receptor distribution is tuned to maximally represent information about ...
Tiberiu Teşileanu, Simona Cocco, Rémi Monasson, Vijay Balasubramanian   +3 more
doaj   +3 more sources