An epigenetic repressor TRIM66 dictates monogenic olfactory receptor expression, neural activity, and olfactory behavior [PDF]
Nature CommunicationsOlfactory receptor gene choice is an intricate example of monogenic and monoallelic expression, where one out of over 1000 receptor genes is transcribed in each olfactory sensory neuron.
Hongqiang Bao +8 more
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Ionotropic crustacean olfactory receptors. [PDF]
PLoS ONE, 2013 The nature of the olfactory receptor in crustaceans, a major group of arthropods, has remained elusive. We report that spiny lobsters, Panulirus argus, express ionotropic receptors (IRs), the insect chemosensory variants of ionotropic glutamate receptors.
Elizabeth A Corey +3 more
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The Neurotransmitter Receptor Architecture of the Mouse Olfactory System
Frontiers in Neuroanatomy, 2021 The uptake, transmission and processing of sensory olfactory information is modulated by inhibitory and excitatory receptors in the olfactory system. Previous studies have focused on the function of individual receptors in distinct brain areas, but the ...
Kimberley Lothmann +3 more
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Mammalian olfactory receptors [PDF]
Frontiers in Cellular Neuroscience, 2009 Perception of chemical stimuli from the environment is essential to most animals; accordingly, they are equipped with a complex olfactory system capable of receiving a nearly unlimited number of odorous substances and pheromones. This enormous task is accomplished by olfactory sensory neurons (OSNs) arranged in several chemosensory compartments in the ...
Fleischer, Joerg +2 more
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Neuromodulation of olfactory sensitivity in the peripheral olfactory organs of the American cockroach, Periplaneta americana. [PDF]
PLoS ONE, 2013 Olfactory sensitivity exhibits daily fluctuations. Several studies have suggested that the olfactory system in insects is modulated by both biogenic amines and neuropeptides. However, molecular and neural mechanisms underlying olfactory modulation in the
Je Won Jung +5 more
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Profiling of olfactory receptor gene expression in whole human olfactory mucosa. [PDF]
PLoS ONE, 2014 Olfactory perception is mediated by a large array of olfactory receptor genes. The human genome contains 851 olfactory receptor gene loci. More than 50% of the loci are annotated as nonfunctional due to frame-disrupting mutations.
Christophe Verbeurgt +5 more
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Tph2-/- female mice restore socio-sexual recognition through upregulating ERα and OTR genes in the amygdala. [PDF]
PLoS ONE, 2018 The central 5-hydroxytryptamine system impairs sociosexual behaviors and olfaction preferences in sexually naive mice. However, it remains unknown whether reproductive experiences impart an effect on the sexual olfactory preferences of female mice ...
Ying Huo +5 more
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Pathogenesis of Olfactory Disorders in COVID-19
Brain Sciences, 2022 Since the outbreak of the SARS-CoV-2 pandemic, olfactory disorders have been reported as a frequent symptom of COVID-19; however, its pathogenesis is still debated.
Laura Ziuzia-Januszewska +1 more
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Ir76b is a Co-receptor for Amine Responses in Drosophila Olfactory Neurons
Frontiers in Cellular Neuroscience, 2021 Two large families of olfactory receptors, the Odorant Receptors (ORs) and Ionotropic Receptors (IRs), mediate responses to most odors in the insect olfactory system. Individual odorant binding “tuning” OrX receptors are expressed by olfactory neurons in
Alina Vulpe, Karen Menuz, Karen Menuz
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Organization and distribution of glomeruli in the bowhead whale olfactory bulb [PDF]
PeerJ, 2015 Although modern baleen whales (Mysticeti) retain a functional olfactory system that includes olfactory bulbs, cranial nerve I and olfactory receptor genes, their olfactory capabilities have been reduced to a great degree.
Takushi Kishida +4 more
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