Adaptation of olfactory receptor abundances for efficient coding
Olfactory receptor usage is highly heterogeneous, with some receptor types being orders of magnitude more abundant than others. We propose an explanation for this striking fact: the receptor distribution is tuned to maximally represent information about ...
Tiberiu Teşileanu+3 more
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The Neurotransmitter Receptor Architecture of the Mouse Olfactory System
The uptake, transmission and processing of sensory olfactory information is modulated by inhibitory and excitatory receptors in the olfactory system. Previous studies have focused on the function of individual receptors in distinct brain areas, but the ...
Kimberley Lothmann+3 more
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Neuromodulation of olfactory sensitivity in the peripheral olfactory organs of the American cockroach, Periplaneta americana. [PDF]
Olfactory sensitivity exhibits daily fluctuations. Several studies have suggested that the olfactory system in insects is modulated by both biogenic amines and neuropeptides. However, molecular and neural mechanisms underlying olfactory modulation in the
Je Won Jung+5 more
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Profiling of olfactory receptor gene expression in whole human olfactory mucosa. [PDF]
Olfactory perception is mediated by a large array of olfactory receptor genes. The human genome contains 851 olfactory receptor gene loci. More than 50% of the loci are annotated as nonfunctional due to frame-disrupting mutations.
Christophe Verbeurgt+5 more
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Pathogenesis of Olfactory Disorders in COVID-19
Since the outbreak of the SARS-CoV-2 pandemic, olfactory disorders have been reported as a frequent symptom of COVID-19; however, its pathogenesis is still debated.
Laura Ziuzia-Januszewska+1 more
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Ir76b is a Co-receptor for Amine Responses in Drosophila Olfactory Neurons
Two large families of olfactory receptors, the Odorant Receptors (ORs) and Ionotropic Receptors (IRs), mediate responses to most odors in the insect olfactory system. Individual odorant binding “tuning” OrX receptors are expressed by olfactory neurons in
Alina Vulpe, Karen Menuz, Karen Menuz
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Organization and distribution of glomeruli in the bowhead whale olfactory bulb [PDF]
Although modern baleen whales (Mysticeti) retain a functional olfactory system that includes olfactory bulbs, cranial nerve I and olfactory receptor genes, their olfactory capabilities have been reduced to a great degree.
Takushi Kishida+4 more
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Tph2-/- female mice restore socio-sexual recognition through upregulating ERα and OTR genes in the amygdala. [PDF]
The central 5-hydroxytryptamine system impairs sociosexual behaviors and olfaction preferences in sexually naive mice. However, it remains unknown whether reproductive experiences impart an effect on the sexual olfactory preferences of female mice ...
Ying Huo+5 more
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The giant pouched rat (Cricetomys ansorgei) olfactory receptor repertoire.
For rodents, olfaction is essential for locating food, recognizing mates and competitors, avoiding predators, and navigating their environment. It is thought that rodents may have expanded olfactory receptor repertoires in order to specialize in ...
Angela R Freeman+2 more
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The molecular mechanism of olfactory cognition is very complicated. Olfactory cognition is initiated by olfactory receptor proteins (odorant receptors), which are activated by olfactory stimuli (ligands). Olfactory receptors are the initial player in the
Elena V. Ignatieva+10 more
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